Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer

First Posted Date
2003-01-27
Last Posted Date
2012-09-24
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
222
Registration Number
NCT00003941
Locations
🇧🇪

Institut Jules Bordet, Brussels (Bruxelles), Belgium

🇩🇪

St. Johannes Hospital - Medical Klinik II, Duisburg, Germany

🇩🇪

Universitaetsklinikum Halle, Halle (Saale), Germany

and more 34 locations

Surgery With or Without Combination Chemotherapy in Treating Patients With Stomach Cancer

Phase 3
Terminated
Conditions
First Posted Date
2003-01-27
Last Posted Date
2012-09-24
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
144
Registration Number
NCT00004099
Locations
🇧🇪

Institut Jules Bordet, Brussels, Belgium

🇩🇪

Universitaetsklinik Duesseldorf, Duesseldorf, Germany

🇩🇪

Klinik & Poliklinik fur Strahlentherapie der Universitat zu Koln, Koln, Germany

and more 15 locations

Doxorubicin and Cisplatin With or Without Paclitaxel in Treating Patients With Locally Advanced, Metastatic, and/or Relapsed Endometrial Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2012-09-24
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
141
Registration Number
NCT00052312
Locations
🇧🇪

Universitair Ziekenhuis Antwerpen, Edegem, Belgium

🇪🇸

Hospital Universitario 12 de Octubre, Madrid, Spain

🇪🇸

Instituto Valenciano De Oncologia, Valencia, Spain

and more 32 locations

Chemotherapy With or Without Surgery in Treating Patients With Recurrent Ovarian Cancer

Phase 3
Terminated
Conditions
First Posted Date
2003-01-27
Last Posted Date
2012-09-24
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
38
Registration Number
NCT00006356
Locations
🇮🇹

Spedali Civili, Brescia, Italy

Chemotherapy Plus Radiation Therapy With or Without Amifostine in Treating Patients With Locally Advanced Cancer of the Nasopharynx

First Posted Date
2003-01-27
Last Posted Date
2012-09-24
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
5
Registration Number
NCT00025298
Locations
🇮🇹

Ospedale Santa Croce, Cuneo, Italy

🇧🇪

U.Z. Gasthuisberg, Leuven, Belgium

🇮🇹

Istituto Nazionale per lo Studio e la Cura dei Tumori, Naples, Italy

and more 9 locations

Combination Chemotherapy in Treating Patients With Advanced Stomach Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2012-05-15
Lead Sponsor
Swiss Group for Clinical Cancer Research
Registration Number
NCT00004873
Locations
🇨🇭

Hopital Cantonal Universitaire de Geneva, Geneva, Switzerland

Combination Chemotherapy in Treating Men With Germ Cell Cancer

First Posted Date
2003-01-27
Last Posted Date
2012-03-06
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
498
Registration Number
NCT00003643
Locations
🇩🇪

Klinikum der Stadt Mannheim, Mannheim, Germany

🇧🇪

Universitair Ziekenhuis Antwerpen, Edegem, Belgium

🇩🇰

Aarhus Universitetshospital - Aarhus Sygehus, Aarhus, Denmark

and more 66 locations

Dimesna in Treating Patients With Solid Tumors Who Are Undergoing Treatment With Cisplatin and Paclitaxel

First Posted Date
2003-01-27
Last Posted Date
2013-01-31
Lead Sponsor
Roswell Park Cancer Institute
Target Recruit Count
2
Registration Number
NCT00003569
Locations
🇺🇸

University of Chicago Cancer Research Center, Chicago, Illinois, United States

🇺🇸

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States

🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

© Copyright 2024. All Rights Reserved by MedPath