Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Combination Chemotherapy and Imatinib Mesylate in Treating Patients With Extensive-Stage Small Cell Lung Cancer

First Posted Date
2003-01-27
Last Posted Date
2015-07-23
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
9
Registration Number
NCT00052494
Locations
🇨🇦

Princess Margaret Hospital, Toronto, Ontario, Canada

Surgery and Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer That Can Be Removed During Surgery

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-12-19
Lead Sponsor
National Cancer Centre, Singapore
Target Recruit Count
200
Registration Number
NCT00003576
Locations
🇸🇬

National Cancer Centre - Singapore, Singapore, Singapore

Combination Chemotherapy in Treating Patients With Stage III Ovarian Epithelial Cancer or Gastrointestinal Cancer

First Posted Date
2003-01-27
Last Posted Date
2011-04-06
Lead Sponsor
NYU Langone Health
Target Recruit Count
45
Registration Number
NCT00005049
Locations
🇺🇸

NYU School of Medicine's Kaplan Comprehensive Cancer Center, New York, New York, United States

Combination Chemotherapy Followed by Surgery in Treating Patients With Stomach Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2011-04-06
Lead Sponsor
NYU Langone Health
Registration Number
NCT00004103
Locations
🇺🇸

NYU Cancer Institute at New York University Medical Center, New York, New York, United States

Capecitabine Combined With Cisplatin in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Phase 1
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2011-04-05
Lead Sponsor
NYU Langone Health
Registration Number
NCT00010023
Locations
🇺🇸

NYU Cancer Institute at New York University Medical Center, New York, New York, United States

Combination Chemotherapy Followed by Chemotherapy and Radiation Therapy and/or Surgery in Treating Patients Who Have Pancreatic Cancer

Phase 1
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2011-03-28
Lead Sponsor
NYU Langone Health
Target Recruit Count
36
Registration Number
NCT00003332
Locations
🇺🇸

NYU School of Medicine's Kaplan Comprehensive Cancer Center, New York, New York, United States

Cisplatin and Etoposide Prior to Radiation Therapy in Treating Patients With CNS Tumors

First Posted Date
2003-01-27
Last Posted Date
2011-03-15
Lead Sponsor
Mayo Clinic
Registration Number
NCT00002472
Locations
🇺🇸

Mayo Clinic Cancer Center, Rochester, Minnesota, United States

🇺🇸

Mayo Clinic Scottsdale, Scottsdale, Arizona, United States

🇺🇸

Mayo Clinic - Jacksonville, Jacksonville, Florida, United States

Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2023-06-22
Lead Sponsor
Eastern Cooperative Oncology Group
Target Recruit Count
33
Registration Number
NCT00003309
Locations
🇺🇸

Vanderbilt-Ingram Cancer Center at Vanderbilt Medical Center, Nashville, Tennessee, United States

🇺🇸

Medical College of Wisconsin Cancer Center, Milwaukee, Wisconsin, United States

🇺🇸

H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

and more 11 locations

Combination Chemotherapy Plus Radiation Therapy To Preserve the Larynx in Patients With Cancer of the Hypopharynx or Larynx

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2018-07-09
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
564
Registration Number
NCT00002839
Locations
🇳🇱

Leiden University Medical Center, Leiden, Netherlands

🇮🇱

Rambam Medical Center, Haifa, Israel

🇧🇪

Algemeen Ziekenhuis Middelheim, Antwerp, Belgium

and more 17 locations

Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2017-01-04
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
682
Registration Number
NCT00003596
Locations
🇺🇸

Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University, Columbus, Ohio, United States

🇺🇸

Riverside Methodist Hospital Cancer Care, Columbus, Ohio, United States

🇺🇸

CCOP - Columbus, Columbus, Ohio, United States

and more 479 locations
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