Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Chemotherapy and Radiation Therapy With or Without Fluorouracil in Treating Patients With Cancer of the Stomach Who Have Undergone Surgery

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2015-11-17
Lead Sponsor
Radiation Therapy Oncology Group
Registration Number
NCT00011960
Locations
🇺🇸

Yale Comprehensive Cancer Center, New Haven, Connecticut, United States

🇺🇸

Providence Alaska Medical Center, Anchorage, Alaska, United States

🇺🇸

John F. Kennedy Medical Center, Edison, New Jersey, United States

and more 66 locations

Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Patients With Central Nervous System Cancer

First Posted Date
2003-01-27
Last Posted Date
2013-02-04
Lead Sponsor
Herbert Irving Comprehensive Cancer Center
Target Recruit Count
30
Registration Number
NCT00007982
Locations
🇺🇸

Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, New York, New York, United States

Combination Chemotherapy Before Surgery in Treating Patients With Mesothelioma of the Lung

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2012-05-15
Lead Sponsor
Swiss Group for Clinical Cancer Research
Target Recruit Count
61
Registration Number
NCT00030745
Locations
🇨🇭

UniversitaetsSpital, Zurich, Switzerland

Radiation Therapy Plus Celecoxib, Fluorouracil, and Cisplatin in Patients With Locally Advanced Cervical Cancer

Phase 1
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-11-19
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
84
Registration Number
NCT00023660
Locations
🇺🇸

Akron General Medical Center, Akron, Ohio, United States

🇺🇸

Akron City Hospital - Summa Health System, Akron, Ohio, United States

🇺🇸

Western Pennsylvania Hospital, Pittsburgh, Pennsylvania, United States

and more 33 locations

Radiation Therapy and Chemotherapy Before and After Surgery in Treating Patients With Esophageal Cancer

First Posted Date
2003-01-27
Last Posted Date
2023-06-28
Lead Sponsor
Eastern Cooperative Oncology Group
Target Recruit Count
97
Registration Number
NCT00033657
Locations
🇺🇸

CCOP - Metro-Minnesota, Saint Louis Park, Minnesota, United States

🇺🇸

Ireland Cancer Center, Cleveland, Ohio, United States

🇺🇸

CCOP - Christiana Care Health Services, Newark, Delaware, United States

and more 20 locations

ALIMTA(Pemetrexed)/Cisplatin and ALIMTA(Pemetrexed)/Carboplatin in Extensive Stage Small Cell Lung Cancer.

Phase 2
Completed
Conditions
First Posted Date
2003-01-14
Last Posted Date
2006-07-20
Lead Sponsor
Eli Lilly and Company
Registration Number
NCT00051506
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY(1-877-285-4559) or speak with your personal physician., Charleston, South Carolina, United States

Phase II Trial of a 96-Hour Continuous Infusion of Paclitaxel Followed by Cisplatin for Patients With Stage III/IV and Relapsed NSCLC

First Posted Date
2002-12-10
Last Posted Date
2008-03-04
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
58
Registration Number
NCT00001450
Locations
🇺🇸

National Cancer Institute (NCI), Bethesda, Maryland, United States

Phase II Neoadjuvant Trial of a Continuous Infusion of Paclitaxel Plus Cisplatin Followed by Chest Radiotherapy for Patients With Stage III Non-Small Cell Lung Cancer

First Posted Date
2002-12-10
Last Posted Date
2008-03-04
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
50
Registration Number
NCT00001499
Locations
🇺🇸

National Cancer Institute (NCI), Bethesda, Maryland, United States

ALIMTA (Pemetrexed) Alone or in Combination With Cisplatin for Patients With Malignant Mesothelioma.

Conditions
First Posted Date
2002-07-04
Last Posted Date
2007-03-15
Lead Sponsor
Eli Lilly and Company
Registration Number
NCT00040625
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY(1-877-285-4559) or speak with your personal physician., Basking Ridge, New Jersey, United States

🇸🇦

For additional information regarding investigative sites for this trial, contact the Clinical Trials support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician, Jeddah, Saudi Arabia

🇪🇬

"For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician.", Cairo, Egypt

Phase I Trial of Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Cisplatin Plus Early Postoperative Intraperitoneal Paclitaxel and 5-FU for Peritoneal Carcinomatosis

Phase 1
Completed
Conditions
First Posted Date
1999-11-04
Last Posted Date
2008-03-04
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
74
Registration Number
NCT00001569
Locations
🇺🇸

National Cancer Institute (NCI), Bethesda, Maryland, United States

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