Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Camrelizumab Combined With Chemotherapy and Apatinib for Extrapulmonary Neuroendocrine Carcinomas

First Posted Date
2021-12-03
Last Posted Date
2021-12-03
Lead Sponsor
Huazhong University of Science and Technology
Target Recruit Count
30
Registration Number
NCT05142865
Locations
🇨🇳

Tongji Hospital,Tongji Medical College Affiliated,Huazhong University of Science & Technology, Wuhan, Hubei, China

A Study to Evaluate Nivolumab in Combination With Ipilimumab Versus Pemetrexed With Cisplatin or Carboplatin for Unresectable Pleural Mesothelioma in Chinese Participants

First Posted Date
2021-11-29
Last Posted Date
2024-06-12
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
100
Registration Number
NCT05136677
Locations
🇨🇳

The First Affiliated Hospital of Zhengzhou Universtiy-Oncology department, Zhengzhou, Henan, China

🇨🇳

Local Institution - 0012, Ningbo, Zhejiang, China

🇨🇳

Beijing Cancer hospital-Thoracic Cancer Department A, Beijing, Beijing, China

and more 23 locations

Neoadjuvant Icotinib With Chemotherapy for Epidermal Growth Factor Receptor(EGFR)-Mutated Resectable Lung Adenocarcinoma

First Posted Date
2021-11-24
Last Posted Date
2021-12-10
Lead Sponsor
Liaoning Tumor Hospital & Institute
Target Recruit Count
45
Registration Number
NCT05132985
Locations
🇨🇳

Liaoning Cancer Hospital & Institute, Shenyang, Liaoning, China

Neoadjuvant Anti-PD-1 and TP Versus TPF on Pathological Response in OSCC

First Posted Date
2021-11-18
Last Posted Date
2023-11-22
Lead Sponsor
Shanghai Jiao Tong University School of Medicine
Target Recruit Count
80
Registration Number
NCT05125055
Locations
🇨🇳

Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China

A Phase II Study of Neoadjuvant Sotorasib in Combination with Cisplatin or Carboplatin and Pemetrexed for Surgically Resectable Stage IIA-IIIB Non-Squamous Non-Small Cell Lung Cancer with a KRAS P.G12C Mutation

First Posted Date
2021-11-12
Last Posted Date
2024-11-01
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
27
Registration Number
NCT05118854
Locations
🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Neoadjuvant and Adjuvant Therapy Studies of Sindilizumab in Resectable Lung Cancer

First Posted Date
2021-11-11
Last Posted Date
2024-03-26
Lead Sponsor
Innovent Biologics (Suzhou) Co. Ltd.
Target Recruit Count
500
Registration Number
NCT05116462
Locations
🇨🇳

Shanghai Pulmonary Hospital, Shanghai, Shanghai, China

A Study of Icotinib With Chemotherapy as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung Cancer

First Posted Date
2021-11-03
Last Posted Date
2021-11-03
Lead Sponsor
Peking University Cancer Hospital & Institute
Target Recruit Count
27
Registration Number
NCT05104788
Locations
🇨🇳

BeijingCancerH, Beijing, China

A Study of Sintilimab Combined With Concurrent Chemoradiation Therapy in Locally Advanced Cervical Cancer

First Posted Date
2021-11-03
Last Posted Date
2021-12-28
Lead Sponsor
The Affiliated Hospital of Xuzhou Medical University
Target Recruit Count
20
Registration Number
NCT05105672
Locations
🇨🇳

The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China

Groningen International Study on Sentinel Nodes in Vulvar Cancer-III

First Posted Date
2021-10-13
Last Posted Date
2023-08-01
Lead Sponsor
University Medical Center Groningen
Target Recruit Count
157
Registration Number
NCT05076942
Locations
🇺🇸

Duke Women's Cancer Care Raleigh, Raleigh, North Carolina, United States

🇺🇸

Memorial Sloan Kettering Monmouth, Middletown, New Jersey, United States

🇺🇸

Memorial Sloan Kettering Nassau, Uniondale, New York, United States

and more 24 locations
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