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Testosterone

Generic Name
Testosterone
Brand Names
Androderm, Androgel, Axiron, Fortesta, Natesto, Striant, Testim, Testopel, Vogelxo
Drug Type
Small Molecule
Chemical Formula
C19H28O2
CAS Number
58-22-0
Unique Ingredient Identifier
3XMK78S47O
Background

Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism. Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics.

Testosterone was isolated from samples and also synthesized in 1935.

Indication

Testosterone is indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.

Associated Conditions
Hypergonadotropic Hypogonadism, Hypogonadotrophic Hypogonadism, Idiopathic Hypogonadotropic Hypogonadism, Puberty, Delayed, Inoperable, metastatic Breast cancer
Associated Therapies
-
Clinical Trials
Related News

Effect of Varying Testosterone Levels on Insulin Sensitivity in Men With Idiopathic Hypogonadotropic Hypogonadism (IHH)

Phase 1
Terminated
Conditions
Kallmann Syndrome
Hypogonadotropic Hypogonadism
Interventions
Drug: Anastrozole Pill
Drug: Testosterone
Drug: Placebo Oral Tablet
First Posted Date
2017-04-18
Last Posted Date
2017-04-18
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
7
Registration Number
NCT03118479
Locations
🇺🇞

Massachusetts General Hospital, Boston, Massachusetts, United States

Subcutaneous vs. Intramuscular Testosterone

Phase 4
Completed
Conditions
Testosterone Deficiency
Hypogonadism, Male
Interventions
Drug: Testosterone
First Posted Date
2017-03-27
Last Posted Date
2019-10-08
Lead Sponsor
Men's Health Boston
Target Recruit Count
4
Registration Number
NCT03091348
Locations
🇺🇞

Men's Health Boston, Chestnut Hill, Massachusetts, United States

Study of Testosterone vs Placebo in Testicular Cancer Survivors

Phase 2
Completed
Conditions
Testicular Cancer
Metabolic Syndrome
Leydig Cell Failure in Adult
Interventions
Drug: Placebos
Drug: Testosterone
First Posted Date
2016-12-13
Last Posted Date
2020-03-06
Lead Sponsor
Mikkel Bandak
Target Recruit Count
69
Registration Number
NCT02991209
Locations
🇩🇰

Rigshospitalet, Copenhagen, Denmark

Muscle Anabolic Interventions to Accelerate Recovery From Hospitalization in Geriatric Patients

Phase 1
Completed
Conditions
Aging
Interventions
Drug: Testosterone
Other: Placebo Injection
Dietary Supplement: Protein Supplement
Other: Placebo supplement
First Posted Date
2016-12-13
Last Posted Date
2024-12-17
Lead Sponsor
The University of Texas Medical Branch, Galveston
Target Recruit Count
80
Registration Number
NCT02990533
Locations
🇺🇞

Jennie Sealy Hospital, Galveston, Texas, United States

Starting a Testosterone and Exercise Program After Hip Injury

Phase 3
Completed
Conditions
Sarcopenia
Frailty
Hip Fracture
Interventions
Drug: Testosterone
Behavioral: Home exercise program
Drug: Placebo gel
Behavioral: Supervised exercise training
Behavioral: Health Education Modules
First Posted Date
2016-10-19
Last Posted Date
2024-03-27
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
129
Registration Number
NCT02938923
Locations
🇺🇞

University of Maryland School of Medicine/Johns Hopkins University, Baltimore, Maryland, United States

🇺🇞

HebrewSenior Life Harvard Medical School, Roslindale, Massachusetts, United States

🇺🇞

Washington University School of Medicine in St. Louis, Saint Louis, Missouri, United States

and more 5 locations

Effect of PROGRESSive Training and Teststerone in Older Frail Men

Phase 2
Completed
Conditions
Muscle Weakness
Interventions
Drug: testosterone
Other: Progressive muscle training
First Posted Date
2016-08-19
Last Posted Date
2024-05-29
Lead Sponsor
University Hospital, Gentofte, Copenhagen
Target Recruit Count
192
Registration Number
NCT02873559
Locations
🇩🇰

Karsten Overgaard, Hellerup, Danmark, Denmark

🇩🇰

Medical Dept. O, Geriatric Section, Herlev, Denmark

Effect of Testosterone Replacement on Exercise Capacity in Hypogonadal Men After a Recent Myocardial Infarction

Phase 2
Withdrawn
Conditions
Hypogonadism
Acute Myocardial Infarction: Rehabilitation Phase
Interventions
Drug: Testosterone
Drug: Normal Saline
First Posted Date
2016-06-16
Last Posted Date
2019-11-21
Lead Sponsor
Texas Tech University Health Sciences Center
Registration Number
NCT02803073
Locations
🇺🇞

Mission Fitness-Medical Center Hospital, Odessa, Texas, United States

A Multinomial Process Model of Moral Judgment

Phase 4
Completed
Conditions
Placebos
Testosterone
Interventions
Drug: Placebo
Drug: Testosterone
First Posted Date
2016-06-14
Last Posted Date
2018-11-23
Lead Sponsor
University of Texas at Austin
Target Recruit Count
220
Registration Number
NCT02799277
Locations
🇺🇞

University of Texas at Austin Department of Psychology, Austin, Texas, United States

Cardiovascular Outcomes of Low Testosterone

Not Applicable
Completed
Conditions
Hypogonadism
Interventions
Drug: Acyline
Drug: Placebo Gel
Drug: Placebo Tablet
Drug: Testosterone Gel
Drug: Arimidex
First Posted Date
2016-05-02
Last Posted Date
2024-10-10
Lead Sponsor
University of Colorado, Denver
Target Recruit Count
232
Registration Number
NCT02758431
Locations
🇺🇞

University of Colorado CCTSI CTRC, Denver, Colorado, United States

Effects of Sex Steroids on the Serotonin System

First Posted Date
2016-03-22
Last Posted Date
2018-10-15
Lead Sponsor
Medical University of Vienna
Target Recruit Count
92
Registration Number
NCT02715232
Locations
🇊🇹

Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria

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