Testosterone

Generic Name
Testosterone
Brand Names
Androderm, Androgel, Axiron, Fortesta, Natesto, Striant, Testim, Testopel, Vogelxo
Drug Type
Small Molecule
Chemical Formula
C19H28O2
CAS Number
58-22-0
Unique Ingredient Identifier
3XMK78S47O
Background

Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism. Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics.

Testosterone was isolated from samples and also synthesized in 1935.

Indication

Testosterone is indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.

Associated Conditions
Hypergonadotropic Hypogonadism, Hypogonadotrophic Hypogonadism, Idiopathic Hypogonadotropic Hypogonadism, Puberty, Delayed, Inoperable, metastatic Breast cancer
Associated Therapies
-

Breast Cancer, Aromatase Inhibitor Therapy, and Sexual Functioning: The Effects of Vaginal Testosterone Therapy

First Posted Date
2012-10-02
Last Posted Date
2014-01-24
Lead Sponsor
Creighton University
Target Recruit Count
12
Registration Number
NCT01697345
Locations
🇺🇸

Nebraska Cancer Specialists/Midwest Cancer Center - Legacy, Omaha, Nebraska, United States

Testosterone and Weight Loss

Phase 2
Completed
Conditions
Interventions
First Posted Date
2012-06-12
Last Posted Date
2016-06-06
Lead Sponsor
Austin Health
Target Recruit Count
100
Registration Number
NCT01616732
Locations
🇦🇺

Austin Health, Heidelberg, Victoria, Australia

Testosterone Administration and ACL Reconstruction in Men

First Posted Date
2012-05-10
Last Posted Date
2022-03-02
Lead Sponsor
University of Southern California
Target Recruit Count
14
Registration Number
NCT01595581
Locations
🇺🇸

University of Southern California, Los Angeles, California, United States

Testosterone in Treating Postmenopausal Patients With Arthralgia Caused by Adjuvant Aromatase Inhibitor Treatment

First Posted Date
2012-04-09
Last Posted Date
2022-11-21
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
227
Registration Number
NCT01573442
Locations
🇺🇸

Rocky Mountain Cancer Centers - Pueblo, Pueblo, Colorado, United States

🇺🇸

Marshfield Clinic - Weston Center, Weston, Wisconsin, United States

🇺🇸

Cedars Sinai Medical Center, Los Angeles, California, United States

and more 525 locations

Testosterone Therapy of Men With Type 2 Diabetes Mellitus (T2DM)

First Posted Date
2012-03-22
Last Posted Date
2013-11-14
Lead Sponsor
Marianne Andersen
Target Recruit Count
43
Registration Number
NCT01560546
Locations
🇩🇰

Department of Endocrinology, Odense University Hospital, Odense, Denmark

The VO2 Increase With Testosterone Addition - Heart Failure (VITA-HF) Trial

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2011-11-10
Last Posted Date
2018-01-23
Lead Sponsor
University of Alberta
Target Recruit Count
318
Registration Number
NCT01469988
Locations
🇨🇦

The University of Alberta (Mazankowski Alberta Heart Institute):, Edmonton, Canada

🇨🇦

Ajax / Pickering, Ajax, Canada

🇨🇦

Foothills Hospital (University of Calgary), Calgary, Canada

and more 4 locations

Testosterone and Alendronate in Hypogonadal Men

First Posted Date
2011-10-27
Last Posted Date
2023-10-12
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
44
Registration Number
NCT01460654
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Safety and Efficacy of Intranasal TBS-1 Treatment of Male Hypogonadism

Phase 3
Completed
Conditions
Interventions
First Posted Date
2011-10-04
Last Posted Date
2018-06-13
Lead Sponsor
Acerus Pharmaceuticals Corporation
Target Recruit Count
306
Registration Number
NCT01446042
Locations
🇺🇸

Coastal Clinical Research, Mobile, Alabama, United States

🇺🇸

Diablo Clinical Reseach Inc., Walnut Creek, California, United States

🇺🇸

Capital Clinical Reseach Center, Olympia, Washington, United States

and more 27 locations

Lybrido for Female Sexual Dysfunction

First Posted Date
2011-09-13
Last Posted Date
2013-07-29
Lead Sponsor
Emotional Brain NY Inc.
Target Recruit Count
196
Registration Number
NCT01432665
Locations
🇺🇸

Compass Research, Orlando, Florida, United States

🇺🇸

Miami Research Associates, South Miami, Florida, United States

🇺🇸

Michael A. Werner, MD PC, Purchase, New York, United States

and more 10 locations

Study on the Effects of Exogenous Testosterone on Threat Perception and Behavioral Avoidance

First Posted Date
2011-08-03
Last Posted Date
2012-10-16
Lead Sponsor
University of Texas at Austin
Target Recruit Count
120
Registration Number
NCT01408498
Locations
🇺🇸

Seay Building, Austin, Texas, United States

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