Potassium chloride

Generic Name: Potassium chloride

Brand Names: Bi-peglyte, Bss, Bss Ophthalmic Solution, Cardioplegic, Citrasate, Colyte, Dextrose and Electrolyte No. 75, Diphen, Eye Stream, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Glycerolyte 57, Golytely, H.E.L.P.bicel, Hemosate Ultra, Ionosol-MB, Isolyte P, Isolyte S, Isolyte S pH 7.4, Isoplate, K 45, K-tab, Klor-con, Lactated Ringers, Moviprep, Naturalyte, Normosol-R, Nulytely, Nxstage Pureflow, Olimel, Peglyte, Periolimel, Phoxillum, Physiolyte, Physiosol, Plasma-lyte, Plasma-lyte 148, Plasma-lyte 148 In 5 % Dextrose, Plasma-lyte R, Plasmalyte A, Plegisol, Plenvu, Pokonza, Prismasol, Procalamine 3, Ringers, Selectbag One, Suflave, Tis-U-sol

Drug Type: Small Molecule

Chemical Formula: ClK

CAS Number: 7447-40-7

Unique Ingredient Identifier: 660YQ98I10

Background: A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.

The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release dosage forms and those products formulated for preparation of solution prior to ingestion.

Indication: For use as an electrolyte replenisher and in the treatment of hypokalemia.

Associated Conditions: Dehydration, Dry Mouth, Hypokalemia, Hypotonic Dehydration, Hypovolaemia, Isotonic Dehydration, Markedly Reduced Food Intake, Metabolic Acidosis, Hypodermoclysis, Mild Metabolic acidosis, Mild, moderate Metabolic Acidosis, Ocular edema

Associated Therapies: Acid- Base Balance, Bowel preparation therapy, Electrolyte replacement, Fluid replacement therapy, Haemofiltration, Hemodialysis Treatment, Parenteral Nutrition, Parenteral rehydration therapy, Plasma Volume Replacement, Urine alkalinization therapy, Fluid and electrolyte maintenance therapy

Clinical Trials

Potassium Chloride in Out-of-hospital Cardiac Arrest Due to Refractory Ventricular Fibrillation

Phase 2

Withdrawn

Conditions: Out-of-hospital Cardiac Arrest (OHCA)

Interventions: Drug: Potassium chloride

First Posted Date: 2020-03-20

Last Posted Date: 2024-01-19

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Registration Number: NCT04316611

Locations: 🇫🇷
AP-HP - SAMU de Paris, Paris, France

Two Low Volume Regimens for Colorectal Cancer Screening Colonoscopy

Phase 4

Completed

Conditions: Colorectal Cancer

Interventions: Drug: Plenvu

First Posted Date: 2020-03-05

Last Posted Date: 2022-09-09

Lead Sponsor: Hospital Clinic of Barcelona

Target Recruit Count: 1002

Registration Number: NCT04297423

Locations: 🇪🇸
Hospital CLinic, Barcelona, Catalonia, Spain

The Use of Osmotic Laxatives Versus Macrogol for Bowel Preparation in Patients Undergoing Colonoscopy

Not Applicable

Conditions: Colorectal Disorders

Interventions: Drug: Eziklen®
Drug: MoviPrep

First Posted Date: 2020-01-13

Last Posted Date: 2020-05-19

Lead Sponsor: Russian Society of Colorectal Surgeons

Target Recruit Count: 98

Registration Number: NCT04225793

Locations: 🇷🇺
Clinic of Colorectal and Minimally invasive surgery, Moscow, Russian Federation

Histidine-Tryptophan-Ketoglutarate Solution Versus Blood Cardioplegia in CABG

Early Phase 1

Completed

Conditions: Cardioplegia Solution Adverse Reaction

Interventions: Drug: HTK cardioplegic solution
Drug: blood cardioplegia

First Posted Date: 2019-12-18

Last Posted Date: 2020-05-07

Lead Sponsor: Ain Shams University

Target Recruit Count: 320

Registration Number: NCT04203680

Locations: 🇪🇬
Ain Shams university, Cairo, Egypt

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis

Phase 3

Recruiting

Conditions: Shock
Septic

Interventions: Drug: Normal Saline
Drug: Lactated Ringer
Drug: Plasma-lyte

First Posted Date: 2019-09-25

Last Posted Date: 2024-07-26

Lead Sponsor: Children's Hospital of Philadelphia

Target Recruit Count: 8800

Registration Number: NCT04102371

Locations: 🇺🇸
UCSF Benioff Children's Hospital, San Francisco, California, United States
🇺🇸
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
🇺🇸
Primary Children's: University of Utah, Salt Lake City, Utah, United States

and more 21 locations

The Cardioprotective Effects of Adding Ozone To Cardioplegic Solution in Adult Cardiac Surgery

Phase 2

Conditions: Ischemic Heart Disease

Interventions: Drug: Cardioplegic Solutions
Drug: Ozone

First Posted Date: 2019-03-15

Last Posted Date: 2019-03-19

Lead Sponsor: Assiut University

Target Recruit Count: 40

Registration Number: NCT03876067

Better Evidence for Selecting Transplant Fluids

Phase 3

Completed

Conditions: Delayed Graft Function
End Stage Kidney Disease
Kidney Transplant; Complications

Interventions: Drug: 0.9% SODIUM CHLORIDE 9g/L injection BP
Drug: Plasma-Lyte 148 (approx. pH 7.4) IV Infusion

First Posted Date: 2019-02-04

Last Posted Date: 2024-10-15

Lead Sponsor: The University of Queensland

Target Recruit Count: 808

Registration Number: NCT03829488

Locations: 🇦🇺
Monash Children's Hospital, Melbourne, Victoria, Australia
🇳🇿
Wellington Hospital, Wellington, New Zealand
🇦🇺
Prince of Wales Hospital, Sydney, New South Wales, Australia

and more 15 locations