Gabapentin

Generic Name
Gabapentin
Brand Names
Gralise, Neurontin
Drug Type
Small Molecule
Chemical Formula
C9H17NO2
CAS Number
60142-96-3
Unique Ingredient Identifier
6CW7F3G59X
Background

Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures - today it is also widely used to treat neuropathic pain. Gabapentin has some stark advantages ...

Indication

In the United States, gabapentin is officially indicated for the treatment of postherpetic neuralgia in adults and for the adjunctive treatment of partial-onset seizures, with or without secondary generalization, in patients 3 years of age and older. In Europe, gabapentin is indicated for adjunctive therapy in the treatment of partial-onset seizures, with or...

Associated Conditions
Partial-Onset Seizures, Peripheral Neuropathic Pain, Postherpetic Neuralgia
Associated Therapies
-

Comparative Study Of Pregabalin And Gabapentin As Adjunctive Therapy In Subjects With Partial Seizures

First Posted Date
2007-10-02
Last Posted Date
2021-01-22
Lead Sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Target Recruit Count
482
Registration Number
NCT00537940
Locations
🇸🇻

Clinica de Especialidades Neurologicas, San Salvador, El Salvador

🇬🇹

Private Office, Guatemala, Guatemala

🇸🇻

Instituto de Neurociencias, San Salvador, El Salvador

and more 4 locations

Gabapentin for the Treatment of Neuroleptic-Induced Tremor

Phase 3
Terminated
Conditions
First Posted Date
2007-09-21
Last Posted Date
2007-09-24
Lead Sponsor
Minneapolis Veterans Affairs Medical Center
Target Recruit Count
40
Registration Number
NCT00533455
Locations
🇺🇸

Minneapols VA Medical Center, Minneapolis, Minnesota, United States

Study of Gabapentin Extended Release (G-ER) in the Treatment of Vasomotor (Hot Flashes/Hot Flushes) Symptoms in Postmenopausal Women

First Posted Date
2007-08-06
Last Posted Date
2011-06-08
Lead Sponsor
Depomed
Target Recruit Count
108
Registration Number
NCT00511953

Gabapentin Treatment of Benzodiazepine Abuse in Methadone Maintenance Patients

First Posted Date
2007-01-11
Last Posted Date
2019-04-24
Lead Sponsor
New York State Psychiatric Institute
Target Recruit Count
19
Registration Number
NCT00420771
Locations
🇺🇸

Bridge Plaza Treatment and Rehabilitation Clinic, Long Island City, New York, United States

Gabapentin Treatment of Cannabis Dependence

Phase 2
Completed
Conditions
Interventions
First Posted Date
2006-11-02
Last Posted Date
2017-02-10
Lead Sponsor
The Scripps Research Institute
Target Recruit Count
50
Registration Number
NCT00395044
Locations
🇺🇸

The Scripps Research Institute, La Jolla, California, United States

To Evaluate if the Medication Gabapentin Lessens Vulvar Pain

First Posted Date
2006-10-19
Last Posted Date
2017-07-31
Lead Sponsor
Colleen Stockdale
Target Recruit Count
9
Registration Number
NCT00390013
Locations
🇺🇸

University of Iowa Hospital and Clinics, Iowa City, Iowa, United States

An Open-Label Comparison of Duloxetine to Other Alternatives for the Management of Diabetic Peripheral Neuropathic Pain

First Posted Date
2006-10-11
Last Posted Date
2011-07-26
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
407
Registration Number
NCT00385671
Locations
🇩🇪

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Siegen, Germany

Comparing Gabapentin and Amitriptyline for the Treatment of Neuropathic Pain in Children and Adolescents

Phase 3
Completed
Conditions
Interventions
First Posted Date
2006-04-07
Last Posted Date
2020-10-20
Lead Sponsor
The Hospital for Sick Children
Target Recruit Count
34
Registration Number
NCT00312260
Locations
🇨🇦

The Hospital for Sick Children, Toronto, Ontario, Canada

Preanalgesic Effect of Gabapentin in Total Knee Repair

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2006-01-19
Last Posted Date
2016-10-26
Lead Sponsor
Texas Health Resources
Target Recruit Count
24
Registration Number
NCT00279487
Locations
🇺🇸

Presbyterian Hospital of Dallas, Dallas, Texas, United States

The Effect of Gabapentin on the Sensation and Impact of Tinnitus

Phase 2
Completed
Conditions
First Posted Date
2005-11-22
Last Posted Date
2005-11-22
Lead Sponsor
Tinnitus Research Consortium
Target Recruit Count
40
Registration Number
NCT00257270
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