Bisacodyl
- Generic Name
- Bisacodyl
- Brand Names
- Alophen Reformulated Jan 2008, Bi-peglyte, Bisac-evac, Carters Little Pills, Dulcolax, Fleet Mineral Oil, Gavilyte-H and Bisacodyl
- Drug Type
- Small Molecule
- Chemical Formula
- C22H19NO4
- CAS Number
- 603-50-9
- Unique Ingredient Identifier
- 10X0709Y6I
- Background
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).
Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
- Indication
Bisacodyl is indicated to relieve occasional constipation and irregularity.
- Associated Conditions
- Bowel movement irregularity, Constipation, Occasional Constipation
- Associated Therapies
- Bowel preparation therapy
A Study to Evaluate the Drug Levels of BMS-986166 in Healthy Male Participants
- First Posted Date
- 2022-06-08
- Last Posted Date
- 2023-03-22
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 7
- Registration Number
- NCT05409157
- Locations
- 🇺🇸
Local Institution - 0001, Madison, Wisconsin, United States
RELISTOR's Effects on Opioid-Induced Constipation
- First Posted Date
- 2021-06-18
- Last Posted Date
- 2022-05-03
- Lead Sponsor
- Methodist Health System
- Registration Number
- NCT04930237
- Locations
- 🇺🇸
Methodist Moody Brain and Spine Institute, Methodist Dallas Medical Center, Dallas, Texas, United States
Defecation Patterns in Constipated Patients
- Conditions
- Interventions
- First Posted Date
- 2021-05-26
- Last Posted Date
- 2024-01-10
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 130
- Registration Number
- NCT04903470
- Locations
- 🇺🇸
University of California San Diego, La Jolla, California, United States
Effect of PEG, Bisacodyl and Prucalopride on Colonic Motility in Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2017-09-12
- Last Posted Date
- 2017-09-12
- Lead Sponsor
- University Hospital, Gasthuisberg
- Target Recruit Count
- 10
- Registration Number
- NCT03279341
- Locations
- 🇧🇪
TARGID, Leuven, Belgium
Reclassifying Constipation Using Imaging and Manometry
- First Posted Date
- 2017-07-21
- Last Posted Date
- 2020-07-07
- Lead Sponsor
- University of Nottingham
- Target Recruit Count
- 120
- Registration Number
- NCT03226145
- Locations
- 🇬🇧
Queen Mary University of London, London, United Kingdom
🇬🇧University College London, London, United Kingdom
🇬🇧University of Nottingham, Nottingham, Notts, United Kingdom
Comparison of Low Volume PEG-Asc and Lower Volume PEG-Asc With Bisacodyl
- Conditions
- Interventions
- First Posted Date
- 2016-12-02
- Last Posted Date
- 2016-12-02
- Lead Sponsor
- Korea University Anam Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT02980562
Treating Anorectal Dysfunction in MS
- Conditions
- Interventions
- First Posted Date
- 2015-11-20
- Last Posted Date
- 2020-01-22
- Lead Sponsor
- David Levinthal
- Target Recruit Count
- 11
- Registration Number
- NCT02609607
- Locations
- 🇺🇸
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Optimization of the Bowel Preparation Regimen for the PillCam® COLON 2 Capsule Endoscopy Procedure
- First Posted Date
- 2015-06-25
- Last Posted Date
- 2017-03-07
- Lead Sponsor
- Medtronic - MITG
- Target Recruit Count
- 122
- Registration Number
- NCT02481219
- Locations
- 🇺🇸
Franklin Gastroenterology, PLLC, Franklin, Tennessee, United States
🇺🇸Indiana University Hospital, Indianapolis, Indiana, United States
🇺🇸Pinnacle Research Group, LLC, Anniston, Alabama, United States
A Study Comparing Picoprep With Mannitol and Bisacodyl for Colon Cleansing in Preparation for Colonoscopy
- Conditions
- Interventions
- First Posted Date
- 2015-03-12
- Last Posted Date
- 2016-01-12
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 184
- Registration Number
- NCT02386449
- Locations
- 🇧🇷
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (there may be other sites in this country), Sao Paulo, Brazil
Efficacy and Tolerability of Bisacodyl Sugar Coated Tablets, Simeticone Chewing Tablets and Their Combination in Constipation and Bloatedness
- First Posted Date
- 2014-08-08
- Last Posted Date
- 2014-08-08
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 30
- Registration Number
- NCT02211976
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.