Telmisartan
- Generic Name
- Telmisartan
- Brand Names
- Actelsar Hct, Micardis, Micardis-hct, Pritor, Twynsta, Tolura, Kinzalmono (previously Telmisartan Boehringer Ingelheim Pharma KG), Telmisartan Teva Pharma, Telmisartan Actavis
- Drug Type
- Small Molecule
- Chemical Formula
- C33H30N4O2
- CAS Number
- 144701-48-4
- Unique Ingredient Identifier
- U5SYW473RQ
- Background
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure. Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.
- Indication
Used alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart failure (only in patients who cannot tolerate ACE inhibitors).
- Associated Conditions
- Cardiovascular Events, Diabetic Nephropathy, Heart Failure, Hypertension
- Associated Therapies
- -
Analysis of Telmisartan Administered With Antiretroviral Therapy (ART) in Patients With Acute HIV Infection
- First Posted Date
- 2014-06-23
- Last Posted Date
- 2020-03-09
- Lead Sponsor
- Yale University
- Target Recruit Count
- 21
- Registration Number
- NCT02170246
- Locations
- š¹š
Chulalongkorn University Hospital, Bangkok, Thailand
š¹šThai Red Cross AIDS Research Centre, Bangkok, Thailand
Drug-drug Interaction Study (Telmisartan, Amlodipine, Chlorthalidone)
- Conditions
- Interventions
- First Posted Date
- 2014-06-02
- Last Posted Date
- 2014-11-19
- Lead Sponsor
- Yuhan Corporation
- Target Recruit Count
- 66
- Registration Number
- NCT02152969
- Locations
- š°š·
The Catholic University of Korea Seoul St.Mary's Hospital, Seoul, Korea, Republic of
Telmisartan vs. Perindopril in Mild-Moderate Alzheimer's Disease Patients
- First Posted Date
- 2014-03-12
- Last Posted Date
- 2022-05-04
- Lead Sponsor
- Sunnybrook Health Sciences Centre
- Target Recruit Count
- 150
- Registration Number
- NCT02085265
- Locations
- šØš¦
Hamilton General Hospital, Hamilton, Ontario, Canada
šØš¦Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
šØš¦Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada
A Study to Explore the Effects of Azilsartan Compared to Telmisartan on Insulin Resistance of Patients With Essential Hypertension on Type 2 Diabetes Mellitus by HOMA-R
- Conditions
- Interventions
- First Posted Date
- 2014-03-06
- Last Posted Date
- 2017-08-02
- Lead Sponsor
- Takeda
- Target Recruit Count
- 33
- Registration Number
- NCT02079805
Comparative Study of the Effects of Telmisartan and Nebivolol
- First Posted Date
- 2014-02-07
- Last Posted Date
- 2014-02-07
- Lead Sponsor
- Aristotle University Of Thessaloniki
- Target Recruit Count
- 80
- Registration Number
- NCT02057328
- Locations
- š¬š·
Hypertension-ABPM Center 3rd department of Internal Medicine, Thessaloniki, Greece
Non-invasive Haemodynamic Assessment in Hypertension
- Conditions
- Interventions
- First Posted Date
- 2013-11-27
- Last Posted Date
- 2018-03-13
- Target Recruit Count
- 144
- Registration Number
- NCT01996085
- Locations
- šµš±
Military Institute of Medicine, Warsaw, Mazovia, Poland
Telmisartan to Reduce AIDS-Related Fibrotic and Inflammatory Contributors (TRAFIC Study)
- First Posted Date
- 2013-08-27
- Last Posted Date
- 2021-08-03
- Target Recruit Count
- 58
- Registration Number
- NCT01928927
- Locations
- šŗšø
UCLA CARE Center CRS (601), Los Angeles, California, United States
šŗšøUniversity of Rochester Adult HIV Therapeutic Strategies Network CRS (31787), Rochester, New York, United States
šŗšøWashington U CRS (2101), Saint Louis, Missouri, United States
Efficacy and Safety Study of YH16410 Versus Rosuvastatin and Telmisartan Monotherapies in Patients With Hypertension and Hyperlipidemia
- Conditions
- Interventions
- First Posted Date
- 2013-08-02
- Last Posted Date
- 2014-07-08
- Lead Sponsor
- Yuhan Corporation
- Target Recruit Count
- 210
- Registration Number
- NCT01914432
- Locations
- š°š·
Seoul National University Hospital, Seoul, Korea, Republic of
HALT Progression of Polycystic Kidney Disease Study B
- Conditions
- Interventions
- First Posted Date
- 2013-06-25
- Last Posted Date
- 2020-04-22
- Target Recruit Count
- 486
- Registration Number
- NCT01885559
- Locations
- šŗšø
University of Colorado Health Sciences Center, Aurora, Colorado, United States
šŗšøEmory University School of Medicine, Atlanta, Georgia, United States
šŗšøTufts University-New England Medical Center, Boston, Massachusetts, United States
HIGH Altitude CArdiovascular REsearch in the ANDES
- Conditions
- Interventions
- First Posted Date
- 2013-04-12
- Last Posted Date
- 2013-04-12
- Lead Sponsor
- Istituto Auxologico Italiano
- Target Recruit Count
- 100
- Registration Number
- NCT01830530
- Locations
- šµšŖ
Universidad Peruana Cayetano Heredia, Lima, Peru
Drug Development Updates
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