Nifedipine
- Generic Name
- Nifedipine
- Brand Names
- Adalat, Afeditab CR, Nifediac, Nifedical, Procardia
- Drug Type
- Small Molecule
- Chemical Formula
- C17H18N2O6
- CAS Number
- 21829-25-4
- Unique Ingredient Identifier
- I9ZF7L6G2L
- Background
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine. Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and lo...
- Indication
Nifedipine capsules are indicated to treat vasospastic angina and chronic stable angina. Extended release tablets are indicated to treat vasospastic angina, chronic stable angina, and hypertension.
- Associated Conditions
- Achalasia, Chronic Stable Angina Pectoris, Fissure;Anal, Hypertension, Hypertensive Emergency, Premature Labour, Proctalgia, Pulmonary Edemas, Pulmonary Hypertension (PH), Raynaud's Phenomenon, Ureteral Calculus, Vasospastic Angina
- Associated Therapies
- -
Comparative Study of Intravenous Labetalol Versus Intravenous Nitroglycerin Versus Sublingual Nifedipine
- Conditions
- Interventions
- First Posted Date
- 2024-02-20
- Last Posted Date
- 2024-02-20
- Lead Sponsor
- Sohag University
- Target Recruit Count
- 60
- Registration Number
- NCT06265415
Treatment of Elevated Blood Pressures in Early Pregnancy
- Conditions
- Interventions
- First Posted Date
- 2023-07-20
- Last Posted Date
- 2024-11-21
- Lead Sponsor
- Marshall University
- Target Recruit Count
- 2
- Registration Number
- NCT05955040
- Locations
- 🇺🇸
Marshall Obstetrics and Gynecology, Huntington, West Virginia, United States
The Treatment of Magnesium Sulfate and Nifedipine in Preterm Labor Threat
- Conditions
- Interventions
- First Posted Date
- 2022-08-29
- Last Posted Date
- 2022-09-15
- Lead Sponsor
- Konya Meram State Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT05520021
- Locations
- 🇹🇷
Hasan Ali Inal, Antalya, Turkey
Postpartum Hypertension Study
- Conditions
- Interventions
- First Posted Date
- 2021-12-01
- Last Posted Date
- 2024-03-18
- Lead Sponsor
- Columbia University
- Target Recruit Count
- 104
- Registration Number
- NCT05139238
- Locations
- 🇺🇸
Columbia University Irving Medical Center, New York, New York, United States
Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy
- First Posted Date
- 2021-02-16
- Last Posted Date
- 2024-03-13
- Lead Sponsor
- Marshall University
- Target Recruit Count
- 60
- Registration Number
- NCT04755764
- Locations
- 🇺🇸
Maternal Hypertension Center at Cabell Huntington Hospital, Huntington, West Virginia, United States
Efficacy of Nifedipine Versus Hydralazine in Management of Severe Hypertension in Pregnancy
- First Posted Date
- 2020-06-17
- Last Posted Date
- 2020-06-17
- Lead Sponsor
- Adebayo Joshua Adeniyi
- Target Recruit Count
- 69
- Registration Number
- NCT04435210
- Locations
- 🇳🇬
Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi, Nigeria
Vaginal Indomethacin for Preterm Labor
- Conditions
- Interventions
- First Posted Date
- 2020-05-27
- Last Posted Date
- 2020-08-11
- Lead Sponsor
- Hadassah Medical Organization
- Target Recruit Count
- 300
- Registration Number
- NCT04404686
Non-Invasive Positive Pressure Ventilation Management of High Altitude Pulmonary Edema
- First Posted Date
- 2020-02-28
- Last Posted Date
- 2020-09-03
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 16
- Registration Number
- NCT04288219
- Locations
- 🇳🇵
Himalayan Rescue Association, Kathmandu, Nepal
Tocolysis in the Management of Preterm Premature Rupture of Membranes Before 34 Weeks of Gestation
- Conditions
- Interventions
- First Posted Date
- 2019-06-05
- Last Posted Date
- 2024-02-13
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 850
- Registration Number
- NCT03976063
- Locations
- 🇫🇷
Trousseau University Hospital, Paris, France
Treating Postictal Symptoms Using Ibuprofen and Nifedipine
- Conditions
- Interventions
- First Posted Date
- 2019-05-14
- Last Posted Date
- 2024-05-09
- Lead Sponsor
- University of Calgary
- Target Recruit Count
- 90
- Registration Number
- NCT03949478
- Locations
- 🇨🇦
Foothills Medical Centre, Calgary, Alberta, Canada
🇨🇦South Health Campus, Calgary, Alberta, Canada
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.