Gliclazide

Generic Name
Gliclazide
Brand Names
Diamicron
Drug Type
Small Molecule
Chemical Formula
C15H21N3O3S
CAS Number
21187-98-4
Unique Ingredient Identifier
G4PX8C4HKV
Background

Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It has been classified differently according to its drug properties in which based on its chemical structure, gliclazide is considered a first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release a ...

Indication

For the treatment of NIDDM in conjunction with diet and exercise.

Associated Conditions
Type 2 Diabetes Mellitus
Associated Therapies
-

Effect of Dorzagliatin on Renal Function Outcomes in People With Type 2 Diabetes: a Multicentric, Prospective, Randomized Study.

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-01-24
Last Posted Date
2024-01-24
Lead Sponsor
Yan Bi
Target Recruit Count
106
Registration Number
NCT06222476
Locations
🇨🇳

Division of Endocrinology, the Affiliated Drum Tower Hospital of Nanjing University, Nanjing, Jiangsu, China

Effects of Henagliflozin on the Brain Function in T2DM Patients With Mild Cognitive Impairment: a Randomized, Parallel Controlled Clinical Trial

First Posted Date
2023-10-17
Last Posted Date
2023-10-17
Lead Sponsor
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Target Recruit Count
60
Registration Number
NCT06085703
Locations
🇨🇳

Division of Endocrinology, the Affiliated Drum Tower Hospital of Nanjing University, Nanjing, Jiangsu, China

Interaction Between Omeprazole and Gliclazide in CYP2C19 Normal/ Ultrarapid Metabolisers

First Posted Date
2019-12-13
Last Posted Date
2021-08-18
Lead Sponsor
University of Sarajevo
Target Recruit Count
15
Registration Number
NCT04198948
Locations
🇧🇦

General Hospital Prim. Dr. Abdulah Nakas, Sarajevo, Bosnia and Herzegovina

Study of Sulphonylurea Synergy With Incretins

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2018-10-15
Last Posted Date
2020-02-24
Lead Sponsor
University of Dundee
Target Recruit Count
20
Registration Number
NCT03705195
Locations
🇬🇧

Ninewells Hospital and Medical School, Dundee, United Kingdom

Bioequivalence and Drug - Drug Interaction Study of Metformin/Gliclazide in Healthy Participants

First Posted Date
2018-03-16
Last Posted Date
2019-07-16
Lead Sponsor
Merck KGaA, Darmstadt, Germany
Target Recruit Count
40
Registration Number
NCT03467945
Locations
🇩🇪

Please Contact the Merck KGaA Communication Center, Darmstadt, Germany

Co-administration of Cabergoline and Gliclazide Improve Glycemic Parameters and Lipid Profile in T2DM Patients

Phase 3
Conditions
Interventions
First Posted Date
2017-10-18
Last Posted Date
2018-08-27
Lead Sponsor
Sherief Abd-Elsalam
Target Recruit Count
60
Registration Number
NCT03313661
Locations
🇪🇬

Sherief Abd-Elsalam, Cairo, Egypt

Antidiabetic Effects on Intrahepatic Fat

First Posted Date
2017-03-01
Last Posted Date
2017-03-01
Lead Sponsor
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Target Recruit Count
87
Registration Number
NCT03068065
Locations
🇨🇳

at Division of Endocrinology, the Affiliated Drum Tower Hospital of Nanjing University, Nanjing, Jiangsu, China

HbA1c Variability in Type II Diabetes

First Posted Date
2016-08-25
Last Posted Date
2023-12-14
Lead Sponsor
Weill Cornell Medical College in Qatar
Target Recruit Count
150
Registration Number
NCT02879409
Locations
🇶🇦

Hamad Medical Corporation, Doha, Qatar

Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Gliclazide in Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-05-19
Last Posted Date
2016-05-19
Lead Sponsor
Bial - Portela C S.A.
Target Recruit Count
20
Registration Number
NCT02777671
Locations
🇵🇹

Human Pharmacology Unit, S. Mamede do Coronado, Portugal

Canagliflozin (Invokana™) vs. Standard Dual Therapy Regimen for T2DM During Ramadan

First Posted Date
2016-02-29
Last Posted Date
2020-01-30
Lead Sponsor
University of Leicester
Target Recruit Count
25
Registration Number
NCT02694263
Locations
🇬🇧

University Hospitals of Leicester NHS Trust, Leicester, Leicestershire, United Kingdom

🇬🇧

University Hospitals Birmingham NHS Foundation Trust, Birmingham, West Midlands, United Kingdom

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