DeepMed Research

Monomethyl fumarate

Generic Name: Monomethyl fumarate

Brand Names: Bafiertam

Drug Type: Small Molecule

Chemical Formula: C_₅H_₆O_₄

CAS Number: 2756-87-8

Unique Ingredient Identifier: 45IUB1PX8R

Clinical Trials

Safety of Immunosuppression Minimization in Children and Adolescents After Kidney Transplantation

Phase 1

Completed

Conditions: Kidney Failure, Chronic
Kidney Transplantation
Immunosuppression

Interventions: Drug: Sirolimus
Drug: MMF or Azathioprine

First Posted Date: 2008-10-08

Last Posted Date: 2013-02-15

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 7

Registration Number: NCT00768729

Locations: 🇺🇸
Children's Hospital, Boston, Boston, Massachusetts, United States
🇺🇸
Children's Hospital, Philadelphia, Philadelphia, Pennsylvania, United States
🇺🇸
Children's Hospital of Central California, Madera, California, United States

and more 2 locations

Phase IV Study to Evaluate Calcineurin Inhibitor Reduced, Steroid Free Immunosuppression After Renal Transplantation

Phase 4

Completed

Conditions: Disorder Related to Renal Transplantation

Interventions: Drug: Basiliximab, Tacrolimus, MMF, Prednisolon
Drug: Basiliximab, Tacrolimus, MMF
Drug: Tacrolimus, MMF, rATG

First Posted Date: 2008-07-29

Last Posted Date: 2014-10-01

Lead Sponsor: University Hospital Freiburg

Target Recruit Count: 600

Registration Number: NCT00724022

Locations: 🇩🇪
Universitätsklinikum Heidelberg, Heidelberg, Germany
🇩🇪
Universitätsklinikum München LMU, München, Germany
🇩🇪
Klinikum rechts der Isar der TU München, München, Germany

and more 22 locations

A Randomized Study to Assess the Safety and Efficacy of Prograf vs Prograf-XL in de Novo Liver Transplant Recipients.

Phase 3

Completed

Conditions: Liver Transplantation
Transplantation Immunology
Host vs Graft Reaction

Interventions: Drug: Prograf-XL
Drug: Prograf
Drug: MMF

First Posted Date: 2008-07-22

Last Posted Date: 2009-09-15

Lead Sponsor: Astellas Pharma Inc

Target Recruit Count: 48

Registration Number: NCT00720408

A Randomized Study to Assess the Safety and Efficacy of Prograf vs Prograf-XL in de Novo Kidney Transplant Recipients

Phase 3

Completed

Conditions: Kidney Transplantation
Transplantation Immunology
Host vs Graft Reaction

Interventions: Drug: Prograf-XL
Drug: Prograf
Drug: MMF

First Posted Date: 2008-07-17

Last Posted Date: 2015-12-17

Lead Sponsor: Astellas Pharma Inc

Target Recruit Count: 73

Registration Number: NCT00717678

A Study Designed to Compare the Tolerability of an Increased Dose of Enteric-coated Mycophenolate Acid (MPA) in Renal Transplant Patients Whose Dose of Mycophenolate Mofetil (MMF) Was Reduced Due to Gastrointestinal Symptoms

Phase 4

Terminated

Conditions: Renal Transplantation

Interventions: Drug: Mycophenolate Mofetil (MMF)
Drug: Enteric-coated Mycophenolate Acid (EC-MPA)
Drug: Placebo MMF
Drug: Placebo EC-MPA

First Posted Date: 2008-04-15

Last Posted Date: 2012-08-07

Lead Sponsor: Novartis Pharmaceuticals

Target Recruit Count: 30

Registration Number: NCT00658333

Locations: 🇺🇸
Novarits, Fargo, North Dakota, United States
🇺🇸
Novartis, Charlottesville, Virginia, United States

Gastrointestinal Tolerability of MMF vs EC-MPS in Maintenance Transplant Patients Treated With Calcineurin Inhibitors

Phase 4

Conditions: Organ Transplantation

Interventions: Drug: EC-MPS
Drug: MMF

First Posted Date: 2008-02-11

Last Posted Date: 2009-02-17

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 400

Registration Number: NCT00611494

Locations: 🇨🇦
Toronto General Hospital - Multi Organ Transplant Program, Toronto, Ontario, Canada

MMF After Pediatric Liver Transplantation

Not Applicable

Completed

Conditions: Liver Transplantation
Chronic Kidney Disease

First Posted Date: 2006-08-22

Last Posted Date: 2011-05-20

Lead Sponsor: Hannover Medical School

Target Recruit Count: 25

Registration Number: NCT00367146

Locations: 🇩🇪
Hannover medical School, Hannover, Germany

Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTX

Not Applicable

Completed

Conditions: Mucositis
Graft-versus-host Disease

Interventions: Drug: TAC + MMF
Drug: Tac+MTX

First Posted Date: 2006-08-07

Last Posted Date: 2013-05-03

Lead Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Target Recruit Count: 89

Registration Number: NCT00360685

Locations: 🇺🇸
H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States

Sirolimus & Mycophenolate Mofetil as GVHD Prophylaxis in Myeloablative, Matched Related Donor HCT

Phase 2

Completed

Conditions: Leukemia
Hematologic Diseases
Lymphoma, Non-Hodgkin
Acute GVHD

Interventions: Drug: Sirolimus
Drug: MMF
Drug: BCNU
Drug: CY
Drug: VP-16
Drug: BU
Drug: FTBI

First Posted Date: 2006-07-10

Last Posted Date: 2021-09-23

Lead Sponsor: Stanford University

Target Recruit Count: 11

Registration Number: NCT00350181

Locations: 🇺🇸
Stanford University School of Medicine, Stanford, California, United States

Mycophenolate Mofetil (MMF) in Patients With IgA Nephropathy

Phase 3

Terminated

Conditions: IgA Nephropathy

Interventions: Drug: Mycophenolate Mofetil (MMF)
Drug: MMF Placebo
Drug: ACEi
Drug: FOS

First Posted Date: 2006-04-26

Last Posted Date: 2016-03-07

Lead Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Target Recruit Count: 184

Registration Number: NCT00318474

Locations: 🇺🇸
St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States

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