Betaine
- Generic Name
- Betaine
- Brand Names
- Amversio, Cystadane, EnBrace HR, EnLyte
- Drug Type
- Small Molecule
- Chemical Formula
- C5H11NO2
- CAS Number
- 107-43-7
- Unique Ingredient Identifier
- 3SCV180C9W
- Background
Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function. Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in plasma and urine. Curre...
- Indication
Betaine is indicated for the treatment of homocystinuria in pediatric and adult patients to decrease elevated homocysteine blood levels. Included within the category of homocystinuria are deficiencies or defects in cystathionine beta-synthase (CBS), 5,10-methylenetetrahydrofolate reductase (MTHFR), and cobalamin cofactor metabolism (cbl).
- Associated Conditions
- Homocystinuria, Homocystinuria Due to Cystathionine Beta-Synthase Deficiency, Homocystinuria due to MTHFR deficiency, Homocystinuria due to cobalamin cofactor metabolism (cbl) defect
- Associated Therapies
- -
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