Ropivacaine

Generic Name: Ropivacaine

Brand Names: Naropin

Drug Type: Small Molecule

Chemical Formula: C_₁₇H_₂₆N_₂O

CAS Number: 84057-95-4

Unique Ingredient Identifier: 7IO5LYA57N

Background: Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication: Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions: Acute Pain, Postoperative pain

Associated Therapies: Surgical anesthesia therapy

Clinical Trials

Liposomal Bupivacaine vs Ropivacaine for TAPBs

Phase 3

Recruiting

Conditions: Ropivacaine
Postoperative Analgesia
Liposomal Bupivacaine
Abdominal Tumor

Interventions: Drug: Liposomal Bupivacaine
Drug: Ropivacaine

First Posted Date: 2024-05-28

Last Posted Date: 2024-05-28

Lead Sponsor: Sun Yat-sen University

Target Recruit Count: 74

Registration Number: NCT06430112

Locations: 🇨🇳
Jingdun Xie, Guangzhou, Guangdong, China

Volume Effect in Peng Block for Total Hip Replacement

Completed

Conditions: Post Operative Pain
Anesthesia

Interventions: Drug: Ropivacaine

First Posted Date: 2024-05-24

Last Posted Date: 2024-05-24

Lead Sponsor: Azienda Ospedaliero, Universitaria Pisana

Target Recruit Count: 120

Registration Number: NCT06427551

Locations: 🇮🇹
Edificio 3 - Azienda Ospedaliero Universitaria Pisana Cisanello, Pisa, Toscana, Italy

Comparison of the Ultrasound-guided Paravertebral Nerve Block With Liposomal Bupivacaine Versus Ropivacaine for Post-Surgical Pain After Video-Assisted Thoracoscopic Surgery

Phase 3

Not yet recruiting

Conditions: Analgesia

Interventions: Drug: Liposomal bupivacaine
Drug: Ropivacaine

First Posted Date: 2024-05-08

Last Posted Date: 2024-05-08

Lead Sponsor: Feng Gao

Target Recruit Count: 84

Registration Number: NCT06405724

Locations: 🇨🇳
Tongji Hospital, Wuhan, Hubei, China

Efficacy of Erector Spinae Plane (ESP) Block in Patients With Inflammatory Bowel Disease (IBD)

Not Applicable

Recruiting

Conditions: Opioid Use

Interventions: Drug: normal saline
Drug: Ropivacaine

First Posted Date: 2024-01-29

Last Posted Date: 2024-02-28

Lead Sponsor: Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Target Recruit Count: 90

Registration Number: NCT06230003

Locations: 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada

The Addition of Hydromorphone to Local Anesthetics for the Repair of Inguinal Hernias in Elderly Patients

Not Applicable

Completed

Conditions: Inguinal Hernia

Interventions: Drug: Hydromorphone combined with ropivacaine
Drug: Ropivacaine

First Posted Date: 2024-01-23

Last Posted Date: 2024-01-23

Lead Sponsor: Second Hospital of Jilin University

Target Recruit Count: 63

Registration Number: NCT06218160

Locations: 🇨🇳
Second Hospital of Jilin University, Changchun, Jilin, China

Intrathecal Morphine vs. Intrathecal Morphine and Regional Anesthesia After Cesarean Section.

Phase 4

Suspended

Conditions: Post-operative Pain

Interventions: Procedure: erector spinae plane block (ESP)
Drug: Duramorph
Drug: Ropivacaine
Drug: Bupivacaine Injection

First Posted Date: 2023-11-02

Last Posted Date: 2024-05-22

Lead Sponsor: University of Miami

Target Recruit Count: 100

Registration Number: NCT06114121

Locations: 🇺🇸
University of Miami, Miami, Florida, United States

Testing Regional anesthesia Techniques For Up And Early Discharge Following Knee arthroplasty - a Feasibility Study

Phase 4

Not yet recruiting

Conditions: Arthroplasty, Replacement, Knee

Interventions: Drug: Ropivacaine
Drug: Normal saline

First Posted Date: 2023-09-26

Last Posted Date: 2024-10-22

Lead Sponsor: McMaster University

Target Recruit Count: 226

Registration Number: NCT06054750

Locations: 🇨🇦
St Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada

Efficacy and Safety of Hydromorphone-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor Analgesia

Phase 2

Recruiting

Conditions: Labor Pain
Analgesia

Interventions: Drug: Sufentanil
Drug: Hydromorphone
Drug: Ropivacaine

First Posted Date: 2023-09-14

Last Posted Date: 2023-10-26

Lead Sponsor: Maternal and Child Health Hospital of Hubei Province

Target Recruit Count: 240

Registration Number: NCT06036797

Locations: 🇨🇳
Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei, China

Application of Brachial Plexus Block in Patients Undergoing Cerebral Aneurysm Embolization Via Transradial Approach

Not Applicable

Recruiting

Conditions: Intracranial Aneurysm
Transradial Access(TRA)

Interventions: Drug: Ropivacaine

First Posted Date: 2023-09-13

Last Posted Date: 2024-02-28

Lead Sponsor: The First Affiliated Hospital with Nanjing Medical University

Target Recruit Count: 176

Registration Number: NCT06035692

Locations: 🇨🇳
The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China

Superficial Cervical Plexus Block for Improved Outcomes in Pediatric Otolaryngologic Surgery

Phase 4

Recruiting

Conditions: Otolaryngologic Surgery

Interventions: Drug: Saline
Drug: ropivacaine

First Posted Date: 2023-09-05

Last Posted Date: 2024-12-13

Lead Sponsor: University of Minnesota

Target Recruit Count: 36

Registration Number: NCT06023329

Locations: 🇺🇸
University of Minnesota, Minneapolis, Minnesota, United States

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