Ropivacaine

Generic Name: Ropivacaine

Brand Names: Naropin

Drug Type: Small Molecule

Chemical Formula: C_₁₇H_₂₆N_₂O

CAS Number: 84057-95-4

Unique Ingredient Identifier: 7IO5LYA57N

Background: Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication: Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions: Acute Pain, Postoperative pain

Associated Therapies: Surgical anesthesia therapy

Clinical Trials

Prospective Clinical Trial Comparing Infraclavicular Versus Axillary Approach to Brachial Plexus Block

Not Applicable

Conditions: Scaphoid Fractures
Distal Radius Fractures
Wrist Injury Arthrodesis

Interventions: Drug: Ropivacaine

First Posted Date: 2014-08-05

Last Posted Date: 2014-08-05

Lead Sponsor: Federal University of São Paulo

Target Recruit Count: 46

Registration Number: NCT02208245

Locations: 🇧🇷
Federal University of Sao Paulo - Hospital Sao Paulo, Sao Paulo, Brazil

Spinal Anaesthesia With Levobupivacaine 0.5% and Ropivacaine 0.75% for Lower Limb Orthopaedic Surgery

Phase 4

Completed

Conditions: Lower Limb Surgery

Interventions: Drug: Levobupivacaine
Drug: Ropivacaine

First Posted Date: 2014-07-28

Last Posted Date: 2015-01-21

Lead Sponsor: Aligarh Muslim University

Target Recruit Count: 60

Registration Number: NCT02201784

Locations: 🇮🇳
Jawaharlal Nehru medical college, AMU, Aligarh, Uttar Pradesh, India

Magnesium as Adjuvant for Sciatic Block

Not Applicable

Completed

Conditions: Hallux Valgus

Interventions: Drug: Ropivacaine
Drug: Magnesium Sulfate

First Posted Date: 2014-07-23

Last Posted Date: 2024-08-26

Lead Sponsor: Campus Bio-Medico University

Target Recruit Count: 60

Registration Number: NCT02198547

Locations: 🇮🇹
Campus Bio-Medico, Rome, Italy

Postoperative Analgesia After Caesarean Section Under ALR: TAP Block Versus Catheter Scar Infiltration

Phase 3

Conditions: Scheduled Caesarian Section

Interventions: Device: The infiltration continues catheter
Drug: Ropivacaine

First Posted Date: 2014-07-09

Last Posted Date: 2014-07-09

Lead Sponsor: Assistance Publique Hopitaux De Marseille

Target Recruit Count: 60

Registration Number: NCT02184559

Locations: 🇫🇷
Assistance Publique Hopitaux de Marseille, Marseille, France

The Effect of Tramadol on Interscalene Brachial Plexus Block

Phase 2

Completed

Conditions: Shoulder Fracture
Shoulder Dislocation
Rotator Cuff Injury
Shoulder Arthritis

Interventions: Drug: Ropivacaine - Tramadol
Drug: Ropivacaine

First Posted Date: 2014-07-08

Last Posted Date: 2016-01-05

Lead Sponsor: Asklepieion Voulas General Hospital

Target Recruit Count: 80

Registration Number: NCT02182752

Locations: 🇬🇷
Asklepieion Hospital of Voula, Athens, Attica, Greece

Pulmonary Function and Interscalene Block

Not Applicable

Completed

Conditions: Shoulder Arthroscopy

Interventions: Drug: ropivacaine

First Posted Date: 2014-07-03

Last Posted Date: 2019-02-20

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 50

Registration Number: NCT02181296

Prolongation of Pain Free Time by the Use of Dexamethasone in Peripheral Nerve Blockade

Phase 4

Conditions: Interscalene Block
Shoulder Arthroscopy
Dexamethasone
Low Volume Regional Anesthesia

Interventions: Drug: Dexamethasone acetate
Drug: Placebo
Drug: Ropivacaine

First Posted Date: 2014-06-30

Last Posted Date: 2014-06-30

Lead Sponsor: Landesklinikum Sankt Polten

Target Recruit Count: 109

Registration Number: NCT02178449

Locations: 🇦🇹
Landesklinikum Sankt Pölten, Sankt Pölten, Lower Austria, Austria

Intraoperative Local Anaesthetic and Postoperative Pain

Not Applicable

Completed

Conditions: Postoperative Pain

Interventions: Procedure: Wound infiltration with local anaesthetic
Drug: Ropivacaine

First Posted Date: 2014-06-24

Last Posted Date: 2014-06-24

Lead Sponsor: Hellenic Red Cross Hospital

Target Recruit Count: 400

Registration Number: NCT02171299

Locations: 🇬🇷
"Korgialenio-Benakio", Hellenic Red Cross Athens General Hospital, Greece, Athens, Greece

Pre-op Paravertebral Blocks to Decrease Post-op Pain Following Mastectomy With Immediate Tissue Expander (TE) Reconstruction

Phase 3

Terminated

Conditions: Postoperative Pain
Postoperative Nausea and Vomiting
Quality of Life

Interventions: Drug: Saline
Drug: Ropivacaine

First Posted Date: 2014-06-12

Last Posted Date: 2020-04-16

Lead Sponsor: Johns Hopkins University

Target Recruit Count: 18

Registration Number: NCT02161705

Locations: 🇺🇸
Johns Hopkins University School of Medicine, Baltimore, Maryland, United States

The Use of Intraperitoneal Ropivacaine in Bariatric Bypass Surgery

Phase 3

Completed

Conditions: Bariatric Surgery Candidate

Interventions: Drug: Normal Saline
Drug: Ropivacaine

First Posted Date: 2014-06-03

Last Posted Date: 2019-03-19

Lead Sponsor: Ottawa Hospital Research Institute

Target Recruit Count: 120

Registration Number: NCT02154763

Locations: 🇨🇦
The Ottawa Hospital, Ottawa, Ontario, Canada

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