MedPath

Ropivacaine

Generic Name
Ropivacaine
Brand Names
Naropin
Drug Type
Small Molecule
Chemical Formula
C17H26N2O
CAS Number
84057-95-4
Unique Ingredient Identifier
7IO5LYA57N
Background

Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication

Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions
Acute Pain, Postoperative pain
Associated Therapies
Surgical anesthesia therapy

A Study Investigating Properties of the Transversus Abdominis Plane Block

Not Applicable
Completed
Conditions
Anesthesia, Local
Interventions
First Posted Date
2012-09-06
Last Posted Date
2015-03-20
Lead Sponsor
Hillerod Hospital, Denmark
Target Recruit Count
16
Registration Number
NCT01679392
Locations
🇩🇰

Hillerød Hospital, Hillerød, Denmark

Intraperitoneal Atomization of Ropivacaine During Gynecologic Laparoscopic Surgery

Phase 3
Conditions
Postoperative Pain
Interventions
Drug: placebo (normal saline)
Drug: Ropivacaine
First Posted Date
2012-06-20
Last Posted Date
2012-06-20
Lead Sponsor
University of Padova
Target Recruit Count
200
Registration Number
NCT01623635
Locations
🇮🇹

Azienda Ospedaliera-Università Padova, Padova, Italy

Postoperative Knee Strength Following Total Knee Replacement: A Double-Blinded Randomized Comparison Study

Not Applicable
Completed
Conditions
Total Knee Replacement
Primary Knee Arthroplasty
Interventions
First Posted Date
2012-06-15
Last Posted Date
2013-11-11
Lead Sponsor
University of South Florida
Target Recruit Count
60
Registration Number
NCT01620047
Locations
🇺🇸

Tampa General Hospital, Tampa, Florida, United States

A Study Comparing Continuous Sciatic Nerve Block to Single Shot Sciatic Nerve Block

Phase 4
Terminated
Conditions
Fracture of Foot
Interventions
First Posted Date
2012-06-11
Last Posted Date
2016-08-01
Lead Sponsor
Northwestern University
Target Recruit Count
17
Registration Number
NCT01615939
Locations
🇺🇸

Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States

Is Regional Anesthesia of the Hip Preferable Over Traditional Analgesia in the Acute Stage of the Management of Patients With a Fracture of the Hip

Phase 4
Terminated
Conditions
Hip Fractures
Interventions
First Posted Date
2012-05-08
Last Posted Date
2015-04-21
Lead Sponsor
Landstinget i Värmland
Target Recruit Count
37
Registration Number
NCT01593319
Locations
🇸🇪

Ortopedkliniken, Centralsjukhuset i Karlstad, Karlstad, Värmland, Sweden

Effectiveness of Interscalene Brachial Plexus Block and Intra-articular Injection of Ropivacaine for Post-operative Analgesia in Arthroscopic Shoulder Stabilization Surgery

Not Applicable
Conditions
Postoperative Analgesia
Interventions
Procedure: Intra-articular Ropivacaine injection
Procedure: Interscalene brachial plexus block
Device: Ultrasound guided technique
Drug: Ropivacaine
First Posted Date
2012-05-01
Last Posted Date
2012-05-02
Lead Sponsor
NHS Grampian
Target Recruit Count
60
Registration Number
NCT01589354

Transversus Abdominis Plane (TAP) Versus Local Anesthetic for Lap Appendectomies

Phase 2
Terminated
Conditions
Appendicitis
Interventions
First Posted Date
2012-04-10
Last Posted Date
2015-08-24
Lead Sponsor
Nationwide Children's Hospital
Target Recruit Count
3
Registration Number
NCT01575028
Locations
🇺🇸

Nationwide Children's Hospital, Columbus, Ohio, United States

Effect of Adductor-Canal-Blockade on High Pain Responders After Total Knee Arthroplasty

Phase 4
Completed
Conditions
Pain After Total Knee Arthroplasty
Interventions
Drug: Ropivacaine
Drug: Saline
First Posted Date
2012-03-09
Last Posted Date
2013-01-08
Lead Sponsor
University Hospital, Gentofte, Copenhagen
Target Recruit Count
50
Registration Number
NCT01549704
Locations
🇩🇰

Gentofte Hospital, Copenhagen, Denmark

Local Infiltration Versus Block Against Pains After High Tibial Osteotomy

Phase 4
Completed
Conditions
Malalignment
Osteoarthritis
Interventions
First Posted Date
2012-02-23
Last Posted Date
2016-01-22
Lead Sponsor
Northern Orthopaedic Division, Denmark
Target Recruit Count
60
Registration Number
NCT01537146
Locations
🇩🇰

Northern Orthopaedic Division, Clinik Farsoe, Aalborg University Hospital, Farsoe, Northern Jutland, Denmark

Duration of Leg Nerve Blocks With Dexamethasone Added to Local Anesthetic

Phase 4
Withdrawn
Conditions
Pain
Total Knee Arthroplasty
Interventions
First Posted Date
2012-01-18
Last Posted Date
2013-09-12
Lead Sponsor
University of New Mexico
Registration Number
NCT01511211
Locations
🇺🇸

University of New Mexico Hospital, Albuquerque, New Mexico, United States

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