Bimatoprost

Generic Name
Bimatoprost
Brand Names
Durysta, Latisse, Lumigan
Drug Type
Small Molecule
Chemical Formula
C25H37NO4
CAS Number
155206-00-1
Unique Ingredient Identifier
QXS94885MZ
Background

Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. It has the ability to reduce ocular hypotension, proving effective in conditions such as ocular hypertensio...

Indication

Bimatoprost is used for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

These patients must be intolerant to other intraocular pressure lowering medications or inadequately responsive to other treatments.

Bimatoprost is also indicated to treat eyelash hypotrichosis.

Associated Conditions
Hypotrichosis of the eyelashes, Increased Intra Ocular Pressure (IOP)
Associated Therapies
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An Open-Label Extension Study to Evaluate the Safety of the ForSight VISION5 Product

First Posted Date
2014-05-21
Last Posted Date
2019-02-26
Lead Sponsor
ForSight Vision5, Inc.
Target Recruit Count
75
Registration Number
NCT02143843
Locations
🇺🇸

Scripps Clinic Torrey Pines, La Jolla, California, United States

🇺🇸

Sall Medical Research Center, Artesia, California, United States

🇺🇸

Coastal Research Associates, Atlanta, Georgia, United States

and more 7 locations

Prostaglandin F2-alpha Eye Drops in Thyroid Eye Disease (Bima Study)

First Posted Date
2014-02-11
Last Posted Date
2016-05-06
Lead Sponsor
Cardiff University
Target Recruit Count
31
Registration Number
NCT02059655
Locations
🇬🇧

University Hospital of Wales, Cardiff, United Kingdom

Bimatoprost Ocular Insert Compared to Topical Timolol Solution in Patients With Glaucoma or Ocular Hypertension

First Posted Date
2013-08-05
Last Posted Date
2018-04-20
Lead Sponsor
ForSight Vision5, Inc.
Target Recruit Count
169
Registration Number
NCT01915940
Locations
🇺🇸

Ophthalmology Associates PC, Fort Worth, Texas, United States

🇺🇸

UNC Kittner Eye Center, Chapel Hill, North Carolina, United States

🇺🇸

Scripps Clinic Torrey Pines, La Jolla, California, United States

and more 7 locations

24-hour Control of Intraocular Pressure (IOP) in Ocular Hypertension

First Posted Date
2012-08-02
Last Posted Date
2012-08-02
Lead Sponsor
University of Parma
Target Recruit Count
61
Registration Number
NCT01655758
Locations
🇮🇹

University Eye Clinic, Parma, Italy

A Study Comparing IOP-Lowering Treatments to Bimatoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

First Posted Date
2012-07-20
Last Posted Date
2014-06-13
Lead Sponsor
Allergan
Target Recruit Count
2580
Registration Number
NCT01646151

The Effects of Xalatan, Travatan and Lumigan on Skin Pigmentation Near the Eye

First Posted Date
2008-06-26
Last Posted Date
2016-01-18
Lead Sponsor
Summa Health System
Target Recruit Count
89
Registration Number
NCT00705757
Locations
🇺🇸

Arlington Eye Physicians, Arlington Heights, Illinois, United States

🇺🇸

Summa Health System, Akron, Ohio, United States

A Multicenter Evaluation of Methods to Reduce Hyperemia Associated With Bimatoprost Therapy for Glaucoma or Ocular Hypertension

Phase 4
Completed
Conditions
First Posted Date
2006-07-04
Last Posted Date
2007-06-01
Lead Sponsor
Innovative Medical
Registration Number
NCT00348062
Locations
🇺🇸

Dr. Noecker, Pittsburgh, Pennsylvania, United States

Safety and Efficacy Study of Bimatoprost in Patients With Glaucoma or Ocular Hypertension

Phase 2
Completed
Conditions
First Posted Date
2006-03-09
Last Posted Date
2011-05-30
Lead Sponsor
Allergan
Target Recruit Count
561
Registration Number
NCT00300443
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