Adenosine

Generic Name
Adenosine
Brand Names
Adenocard, Viva-drops Lubricating Eye Drops
Drug Type
Small Molecule
Chemical Formula
C10H13N5O4
CAS Number
58-61-7
Unique Ingredient Identifier
K72T3FS567
Background

The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson]. Adenosine is also indic...

Indication

Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy in patients unable to adequately exercise. It is also indicated to convert sinus rhythm of paroxysmal supraventricular tachycardia.

Associated Conditions
Paroxysmal Supraventricular Tachycardia (PSVT), Pulmonary Arterial Hypertension (PAH), SVT, Supraventricular Tachycardia (SVT)
Associated Therapies
-

ADVANCE MPI 1: Study of Regadenoson Versus Adenoscan® in Patients Undergoing Myocardial Perfusion Imaging (MPI)

Phase 3
Completed
Conditions
Interventions
First Posted Date
2005-09-21
Last Posted Date
2009-11-26
Lead Sponsor
Gilead Sciences
Target Recruit Count
1231
Registration Number
NCT00208299
Locations
🇺🇸

Multiple study locations (see Central Contact); CV Therapeutics, Inc., Palo Alto, California, United States

ADVANCE MPI 2: Study of Regadenoson Versus Adenoscan® in Patients Undergoing Myocardial Perfusion Imaging (MPI)

Phase 3
Completed
Conditions
Interventions
First Posted Date
2005-09-21
Last Posted Date
2009-11-26
Lead Sponsor
Gilead Sciences
Target Recruit Count
787
Registration Number
NCT00208312
Locations
🇺🇸

Multiple study locations (see Central Contact); CV Therapeutics, Inc., Palo Alto, California, United States

Ischemic Injury and Ischemic Preconditioning in Diabetes

First Posted Date
2005-09-16
Last Posted Date
2007-04-05
Lead Sponsor
Radboud University Medical Center
Target Recruit Count
20
Registration Number
NCT00184821
Locations
🇳🇱

Clinical Research Centre Nijmegen; Radboud University Nijmegen Medical Centre, Nijmegen, Gelderland, Netherlands

Adenosine Receptors Influence Ischemia-Reperfusion Injury

Not Applicable
Suspended
Conditions
First Posted Date
2005-09-16
Last Posted Date
2008-03-28
Lead Sponsor
Radboud University Medical Center
Target Recruit Count
8
Registration Number
NCT00184847
Locations
🇳🇱

Radboud University Nijmegen Medical Centre/Department of Pharmacology and Toxicology, Nijmegen, Gelderland, Netherlands

AMP as a Better Delivery System of Adenosine

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2005-09-15
Last Posted Date
2019-05-07
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
13
Registration Number
NCT00179010
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

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