Adenosine
- Generic Name
- Adenosine
- Brand Names
- Adenocard, Viva-drops Lubricating Eye Drops
- Drug Type
- Small Molecule
- Chemical Formula
- C10H13N5O4
- CAS Number
- 58-61-7
- Unique Ingredient Identifier
- K72T3FS567
- Background
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson]. Adenosine is also indic...
- Indication
Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy in patients unable to adequately exercise. It is also indicated to convert sinus rhythm of paroxysmal supraventricular tachycardia.
- Associated Conditions
- Paroxysmal Supraventricular Tachycardia (PSVT), Pulmonary Arterial Hypertension (PAH), SVT, Supraventricular Tachycardia (SVT)
- Associated Therapies
- -
Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young Adults
- First Posted Date
- 2018-11-13
- Last Posted Date
- 2021-07-27
- Lead Sponsor
- Colorado State University
- Target Recruit Count
- 9
- Registration Number
- NCT03738943
- Locations
- 🇺🇸
Human Performance and Clinical Research Laboratory, Fort Collins, Colorado, United States
Adenosine Contrast CorrELations in Evaluating RevAscularizaTION
- Conditions
- Interventions
- First Posted Date
- 2018-06-15
- Last Posted Date
- 2024-07-05
- Lead Sponsor
- Duke University
- Target Recruit Count
- 201
- Registration Number
- NCT03557385
- Locations
- 🇺🇸
Long Beach VA, Long Beach, California, United States
🇺🇸Mercy Hospital, Coon Rapids, Minnesota, United States
🇺🇸Durham VA, Durham, North Carolina, United States
A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular Dysfunction
- Conditions
- Interventions
- First Posted Date
- 2018-05-25
- Last Posted Date
- 2024-01-11
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 165
- Registration Number
- NCT03537586
- Locations
- 🇺🇸
New York University School of Medicine, New York, New York, United States
Adenosine and A2A Receptors in Human Brown Adipose Tissue
- First Posted Date
- 2017-10-31
- Last Posted Date
- 2017-11-06
- Lead Sponsor
- Turku University Hospital
- Target Recruit Count
- 11
- Registration Number
- NCT03327168
Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve
- Conditions
- Interventions
- First Posted Date
- 2017-08-15
- Last Posted Date
- 2020-09-16
- Lead Sponsor
- Duke University
- Target Recruit Count
- 31
- Registration Number
- NCT03249272
- Locations
- 🇺🇸
Duke Cardiovascular Magnetic Resonance Center, Durham, North Carolina, United States
A Dose Titration Study to Assess the Effects of SAR407899 in Patients With MVA and/or Persistent Stable Angina Despite Angiographically Successful PCI
- Conditions
- Interventions
- First Posted Date
- 2017-08-01
- Last Posted Date
- 2022-03-24
- Lead Sponsor
- Sanofi
- Target Recruit Count
- 10
- Registration Number
- NCT03236311
- Locations
- 🇺🇸
Investigational Site Number 8400001, Jacksonville, Florida, United States
🇺🇸Investigational Site Number 8400013, Wellington, Florida, United States
🇩🇰Investigational Site Number 2080001, København Nv, Denmark
Coronary Artery Vasculopathy in Pediatric Heart Transplant Patients
- First Posted Date
- 2017-07-27
- Last Posted Date
- 2017-09-26
- Lead Sponsor
- Bryan Goldstein
- Target Recruit Count
- 22
- Registration Number
- NCT03231371
- Locations
- 🇺🇸
University of MIchigan-Congenital Heart Center, Ann Arbor, Michigan, United States
Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions
- First Posted Date
- 2017-07-14
- Last Posted Date
- 2024-08-19
- Lead Sponsor
- Weill Medical College of Cornell University
- Target Recruit Count
- 100
- Registration Number
- NCT03218137
- Locations
- 🇺🇸
Weill Cornell Medicine, New York, New York, United States
Adenosine to Assess Complete Conduction Block During Catheter Ablation of Paroxysmal Atrial Fibrillation
- First Posted Date
- 2017-01-26
- Last Posted Date
- 2017-12-13
- Lead Sponsor
- University of Michigan
- Target Recruit Count
- 131
- Registration Number
- NCT03032965
- Locations
- 🇺🇸
University of Michigan, Ann Arbor, Michigan, United States
Adenosin to Rapidly Reverse Left Ventricle Impairment in Takotsubo Syndrome
- Conditions
- Interventions
- First Posted Date
- 2016-08-16
- Last Posted Date
- 2018-10-23
- Lead Sponsor
- University Hospital of Ferrara
- Target Recruit Count
- 5
- Registration Number
- NCT02867878
- Locations
- 🇮🇹
University Hospital of Ferrara, Cona, Ferrara, Italy
Drug Development Updates
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