Calcium carbonate
- Generic Name
- Calcium carbonate
- Brand Names
- Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Plus Gas Relief, Alkums, Bayer Womens, Cal Gest, Chooz, Diphen, Duo Fusion, Healthy Mama, Irospan 24/6 Kit, Magnebind 400 Rx, Meijer, Mi-acid Double Strength, Mylanta Tonight, Nutralox, Pepcid Complete, Pepto-bismol, Phazyme, Pregvit, Rolaids Advanced, Rolaids Reformulated Aug 2006, Rolaids Ultra Strength, Titralac, Titralac Plus, Tums
- Drug Type
- Small Molecule
- Chemical Formula
- CCaO3
- CAS Number
- 471-34-1
- Unique Ingredient Identifier
- H0G9379FGK
- Background
Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also be used as a nutritional supplement or to treat hypocalcemia.
- Indication
For relief of heartburn and acid indigestion. May also be used as a nutritional supplement or to treat hypocalcemia.
- Associated Conditions
- Bloating, Calcium Deficiency, Calcium Metabolism Disorders, Calcium and Vitamin D Deficiencies, Colic, Dyspepsia, Gastric Ulcer, Gastroesophageal Reflux, Haemorrhoids, Heartburn, Hot Flashes, Hyperacidity, Hyperphosphataemia, Low Bone Density, Osteodystrophy, Osteomalacia, Osteoporosis, Post Operative Gas, Postmenopausal Osteoporosis, Proctitis, Reflux Acid, Rickets, Vertebral Fractures, Calcium loss, Gastrointestinal ulceration
- Associated Therapies
- Dietary supplementation
Effect of Phosphate Binders on FGF-23 With Concurrent Calcitriol
- Conditions
- Chronic Kidney Disease Stage 3
- Interventions
- First Posted Date
- 2012-12-12
- Last Posted Date
- 2013-02-18
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT01748396
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
A Study to Assess the Pharmacokinetics of Lanthanum Carbonate, Investigate and Compare the Efficacy, Safety and Tolerability of Lanthanum Carbonate With Calcium Carbonate in Hyperphosphataemic Children and Adolescents With Chronic Kidney Disease on Dialysis
- Conditions
- Chronic Kidney DiseaseHyperphosphatemia
- Interventions
- First Posted Date
- 2012-10-01
- Last Posted Date
- 2021-06-10
- Lead Sponsor
- Shire
- Target Recruit Count
- 63
- Registration Number
- NCT01696279
- Locations
- 🇭🇺
Szegedi Tudomanyegyetem Altalanos Orvostudomanyi Kar, Szeged, Hungary
🇨🇿Fakultni nemocnice Ostrava, Ostrava, Czechia
🇩🇪Medizinische Hochschule Hannover, Hannover, Germany
A Pharmacokinetic Study to Evaluate the Effect of Antacids on Raltegravir (MK-0518) in HIV-Infected Participants (MK-0518-247)
- Conditions
- HIV Infections
- Interventions
- First Posted Date
- 2012-06-19
- Last Posted Date
- 2017-03-21
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 27
- Registration Number
- NCT01622673
Role of Calcium And Vitamin D In Nutritional Rickets And It's Management
- Conditions
- Nutritional Rickets
- Interventions
- First Posted Date
- 2012-04-17
- Last Posted Date
- 2012-04-19
- Lead Sponsor
- Lady Hardinge Medical College
- Target Recruit Count
- 67
- Registration Number
- NCT01578434
Outcome Study of Lanthanum Carbonate Compared With Calcium Carbonate in Hemodialysis Patients : Landmark Study
- Conditions
- HemodialysisHyperphosphatemia
- Interventions
- First Posted Date
- 2012-04-16
- Last Posted Date
- 2020-11-30
- Lead Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
- Target Recruit Count
- 2309
- Registration Number
- NCT01578200
- Locations
- 🇯🇵
Showa University, Shinagawa, Tokyo, Japan
Phase III Double-blind Comparative Study of BAY77-1931 (Lanthanum Carbonate) With Calcium Carbonate
- Conditions
- Hyperphosphatemia
- Interventions
- First Posted Date
- 2012-01-23
- Last Posted Date
- 2012-06-08
- Lead Sponsor
- Bayer
- Target Recruit Count
- 259
- Registration Number
- NCT01514851
The Effects of Sevelamer Carbonate on Diabetic Nephropathy
- Conditions
- Diabetic Nephropathy
- Interventions
- First Posted Date
- 2011-12-15
- Last Posted Date
- 2014-04-09
- Lead Sponsor
- Gary Striker
- Target Recruit Count
- 117
- Registration Number
- NCT01493050
- Locations
- 🇺🇸
Beth Israel Medical Center, New York, New York, United States
🇺🇸Icahn School of Medicine at Mount Sinai, New York, New York, United States
Effect of Calcium + Vitamin D Supplementation on Weight Management in Very-low Calcium Consumers
- Conditions
- ObesityOverweight
- Interventions
- Behavioral: Energy restriction
- First Posted Date
- 2011-10-06
- Last Posted Date
- 2012-08-01
- Lead Sponsor
- Changhai Hospital
- Target Recruit Count
- 53
- Registration Number
- NCT01447433
- Locations
- 🇨🇳
Changhai Hospital, Shanghai, China
High Dose Vitamin D and Calcium for Bone Health in Individuals Initiating HAART
- Conditions
- HIV-1 Infection
- Interventions
- Drug: EFV/FTC/TDFDrug: Placebo for calcium carbonateDrug: Placebo for vitamin D3
- First Posted Date
- 2011-07-27
- Last Posted Date
- 2018-10-12
- Lead Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
- Target Recruit Count
- 167
- Registration Number
- NCT01403051
- Locations
- 🇺🇸
Hosp. of the Univ. of Pennsylvania CRS (6201), Philadelphia, Pennsylvania, United States
🇺🇸Harbor-UCLA Med. Ctr. CRS (603), Torrance, California, United States
🇺🇸Stanford CRS (501), Palo Alto, California, United States
Vitamin D and Muscle Strength and Surface (Electromyography) EMG
- Conditions
- Vitamin D Deficiency
- Interventions
- Other: lactose placeboOther: lactose granules and tablets
- First Posted Date
- 2010-08-30
- Last Posted Date
- 2011-06-15
- Lead Sponsor
- Indian Council of Medical Research
- Target Recruit Count
- 170
- Registration Number
- NCT01190683
Drug Development Updates
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