Calcium carbonate
- Generic Name
- Calcium carbonate
- Brand Names
- Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Plus Gas Relief, Alkums, Bayer Womens, Cal Gest, Chooz, Diphen, Duo Fusion, Healthy Mama, Irospan 24/6 Kit, Magnebind 400 Rx, Meijer, Mi-acid Double Strength, Mylanta Tonight, Nutralox, Pepcid Complete, Pepto-bismol, Phazyme, Pregvit, Rolaids Advanced, Rolaids Reformulated Aug 2006, Rolaids Ultra Strength, Titralac, Titralac Plus, Tums
- Drug Type
- Small Molecule
- Chemical Formula
- CCaO3
- CAS Number
- 471-34-1
- Unique Ingredient Identifier
- H0G9379FGK
- Background
Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also be used as a nutritional supplement or to treat hypocalcemia.
- Indication
For relief of heartburn and acid indigestion. May also be used as a nutritional supplement or to treat hypocalcemia.
- Associated Conditions
- Bloating, Calcium Deficiency, Calcium Metabolism Disorders, Calcium and Vitamin D Deficiencies, Colic, Dyspepsia, Gastric Ulcer, Gastroesophageal Reflux, Haemorrhoids, Heartburn, Hot Flashes, Hyperacidity, Hyperphosphataemia, Low Bone Density, Osteodystrophy, Osteomalacia, Osteoporosis, Post Operative Gas, Postmenopausal Osteoporosis, Proctitis, Reflux Acid, Rickets, Vertebral Fractures, Calcium loss, Gastrointestinal ulceration
- Associated Therapies
- Dietary supplementation
Sevelamer Hydrochloride and Femoral and Carotid Intima Media Thickness Progression in End Stage Renal Disease
- Conditions
- End Stage Renal DiseaseHemodialysisIntimal Media Thickness
- Interventions
- First Posted Date
- 2010-01-14
- Last Posted Date
- 2010-01-14
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Target Recruit Count
- 175
- Registration Number
- NCT01049815
- Locations
- 🇮🇱
Tel Aviv Medical Center, Tel Aviv, Israel
🇮🇱Edith Wolfson Medical Center, Holon, Israel
MK-5442 in the Treatment of Osteoporosis in Postmenopausal Women Previously Treated With an Oral Bisphosphonate (MK-5442-012)
- Conditions
- Postmenopausal OsteoporosisOsteoporosis
- Interventions
- Drug: Placebo to MK-5442Drug: Placebo to Alendronate
- First Posted Date
- 2009-10-16
- Last Posted Date
- 2016-01-22
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 526
- Registration Number
- NCT00996801
Vitamin D Supplementation After Parathyroid Surgery
- Conditions
- Primary Hyperparathyroidism
- Interventions
- First Posted Date
- 2009-09-23
- Last Posted Date
- 2019-02-28
- Lead Sponsor
- Karolinska University Hospital
- Target Recruit Count
- 150
- Registration Number
- NCT00982722
- Locations
- 🇸🇪
Karolinska University Hospital, Stockholm, Sweden
🇸🇪Karolinska UH, Stockholm, Sweden
Effect of Sevelamer Carbonate on Oxidative Stress in Patients With Diabetic Nephropathy
- Conditions
- Diabetic Nephropathy
- Interventions
- First Posted Date
- 2009-08-28
- Last Posted Date
- 2011-11-18
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 20
- Registration Number
- NCT00967629
- Locations
- 🇺🇸
Mount Sinai School of Medicine, New York, New York, United States
Effect of Sevelamer on Glucose Tolerance and Insulin Sensitivity in Patients With Chronic Renal Failure (CKD)
- Conditions
- Kidney Failure, ChronicEnd-Stage Renal DiseaseInsulin ResistanceHyperphosphatemia
- Interventions
- First Posted Date
- 2009-02-05
- Last Posted Date
- 2012-09-26
- Lead Sponsor
- Karolinska Institutet
- Registration Number
- NCT00837655
- Locations
- 🇸🇪
Karolinska University Hospital, Stockholm, Sweden
🇸🇪Sahlgrenska University Hospital, Gothenburg, Sweden
Reduce Cardiovascular Calcifications to Reduce QT Interval in Dialysis
- Conditions
- Cardiovascular Mortality
- Interventions
- First Posted Date
- 2008-07-04
- Last Posted Date
- 2013-02-12
- Lead Sponsor
- Azienda Sanitaria ASL Avellino 2
- Target Recruit Count
- 360
- Registration Number
- NCT00710788
- Locations
- 🇮🇹
Nephrology Division, Solofra, Avellino, Italy
A Study to Determine Effective Prophylaxis and Treatment of Nelfinavir-Associated Diarrhea
- Conditions
- Diarrhea
- Interventions
- Other: Calcium carbonate not administered
- First Posted Date
- 2008-04-02
- Last Posted Date
- 2011-06-08
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 17
- Registration Number
- NCT00650637
- Locations
- 🇺🇸
Pfizer Investigational Site, Houston, Texas, United States
Regulation of Bone Formation in Renal Osteodystrophy
- Conditions
- Secondary HyperparathyroidismRenal Osteodystrophy
- Interventions
- First Posted Date
- 2007-11-19
- Last Posted Date
- 2010-01-14
- Target Recruit Count
- 61
- Registration Number
- NCT00560300
Effect of Zoledronic Acid on Chemotherapy Induced Bone Loss
- Conditions
- Non-Hodgkin's LymphomaLymphoma
- Interventions
- First Posted Date
- 2006-07-17
- Last Posted Date
- 2013-07-02
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 135
- Registration Number
- NCT00352846
- Locations
- 🇺🇸
UT MD Anderson Cancer Center, Houston, Texas, United States
Pamidronate, Vitamin D, and Calcium for the Bone Disease of Kidney and Heart Transplantation
- Conditions
- Transplant Bone Disease
- Interventions
- First Posted Date
- 2006-03-14
- Last Posted Date
- 2018-08-29
- Lead Sponsor
- Providence Health & Services
- Target Recruit Count
- 43
- Registration Number
- NCT00302627
- Locations
- 🇺🇸
Providence Medical Research Center, Spokane, Washington, United States
Drug Development Updates
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