Budesonide

Generic Name
Budesonide
Brand Names
Airsupra, Breyna, Breztri, Cortiment, Entocort, Pulmicort, Pulmicort Turbuhaler, Rhinocort, Symbicort, Tarpeyo, Uceris, Jorveza, Kinpeygo
Drug Type
Small Molecule
Chemical Formula
C25H34O6
CAS Number
51333-22-3
Unique Ingredient Identifier
Q3OKS62Q6X
Background

Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.

Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product with formoterol.

Indication

Budesonide extended release capsules are indicated for the treatment and maintenance of mild to moderate Crohn’s disease. Various inhaled budesonide products are indicated for prophylactic therapy in asthma and to reduce exacerbations of COPD. A budesonide nasal spray is available over the counter for symptoms of hay fever and upper respiratory allergies. E...

Associated Conditions
Allergic Reaction, Allergic Rhinitis (AR), Asthma, Bronchoconstriction, Chronic Obstructive Pulmonary Disease (COPD), Collagenous Colitis, Crohn's Disease (CD), Eosinophilic Esophagitis, Exacerbation of asthma, Nasal Congestion, Nasal Polyps, Proteinuria, Pruritus, Rhino Sinusitis, Ulcerative Colitis, Vasomotor Rhinitis, Corticosteroid-responsive dermatoses, Mild Crohn’s Disease, Moderate Crohn’s Disease
Associated Therapies
Maintenance therapy
Clinical Trials
Related News

Bioavailability Study of SYN006, Pulmicort pMDI and Meptin Air in Healthy Adult.

First Posted Date
2014-06-17
Last Posted Date
2015-06-03
Lead Sponsor
Intech Biopharm Ltd.
Target Recruit Count
24
Registration Number
NCT02165046
Locations
🇨🇳

Tri-Service General Hospital, Taipei, Taiwan

Prospective Evaluation of Budesonide for Prevention of Esophageal Strictures After Endotherapy

Phase 2
Completed
Conditions
Esophageal Stricture
Interventions
Drug: Budesonide
First Posted Date
2014-02-24
Last Posted Date
2020-06-16
Lead Sponsor
Mayo Clinic
Target Recruit Count
90
Registration Number
NCT02069847
Locations
🇺🇸

Mayo Clinic in Florida, Jacksonville, Florida, United States

Comparison Between Budesonide and Dexamethasone Treatments for Respiratory Discomfort After Extubation on Children

Not Applicable
Conditions
Stridor
Interventions
Drug: Budesonide
Drug: Dexamethasone
First Posted Date
2014-02-06
Last Posted Date
2014-02-06
Lead Sponsor
Hospital Israelita Albert Einstein
Target Recruit Count
70
Registration Number
NCT02056379
Locations
🇧🇷

Instituto Israelita de Ensino e Pesquisa Albert Einstein 's (IIEP), São Paulo, Brazil

Study to Evaluate Efficacy/Safety of Combination Budesonide/Indacaterol vs Fluticasone/Salmeterol in Patients With COPD

First Posted Date
2014-02-05
Last Posted Date
2017-04-18
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
222
Registration Number
NCT02055352
Locations
🇵🇦

Novartis Investigative Site, Panama City, Panamá, Panama

Effects and Safety of Budesonide Inhalation Suspension Via Transnasal Nebulization in Nasal Polyps

Phase 2
Completed
Conditions
Nasal Polyps
Interventions
Other: placebo
Drug: budesonide
First Posted Date
2013-12-31
Last Posted Date
2014-10-10
Lead Sponsor
Beijing Tongren Hospital
Target Recruit Count
57
Registration Number
NCT02024659
Locations
🇨🇳

Beijing Tongren Hospital, Beijing, Beijing, China

Curosurf/Budesonide for Infants With Respiratory Distress Syndrome

Not Applicable
Completed
Conditions
Respiratory Distress Syndrome
Interventions
Drug: Budesonide
First Posted Date
2013-12-17
Last Posted Date
2017-12-07
Lead Sponsor
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Target Recruit Count
300
Registration Number
NCT02013115
Locations
🇨🇳

Department of Pediatrics, Daping Hospital, Research Institute of Surgery, Third Military Medical University, Chongqing, Chongqing, China

Does Asthma Phenotype Have Impact on Disease Control

Completed
Conditions
Asthma
Interventions
Drug: Pulmicort
First Posted Date
2013-11-07
Last Posted Date
2020-02-05
Lead Sponsor
Bispebjerg Hospital
Target Recruit Count
80
Registration Number
NCT01978678
Locations
🇩🇰

Respiratory research unit, Bispebjerg University Hospital, Copenhagen, Denmark

🇩🇰

Department of Respiratory Medicine, L, Bispebjerg Hospital,, Copenhagen, NV, Denmark

Asthma Biomarkers for Predicting Response to Therapy

Not Applicable
Conditions
Asthma
Interventions
Drug: Budesonide
First Posted Date
2013-10-31
Last Posted Date
2016-05-16
Lead Sponsor
Tongji Hospital
Target Recruit Count
148
Registration Number
NCT01973751
Locations
🇨🇳

Department of Respiratory and Critical Care Medicine, Tongji Hospital, Wuhan, Hubei, China

Buparid/PARI SINUS Versus Budes® Nasal Spray in the Therapy of Chronic Rhinosinusitis

Phase 1
Completed
Conditions
Rhinosinusitis
Interventions
Drug: Budesonide
First Posted Date
2013-10-08
Last Posted Date
2022-04-12
Lead Sponsor
Pari Pharma GmbH
Target Recruit Count
19
Registration Number
NCT01955980
Locations
🇩🇪

UNIVERSITÄTSMEDIZIN der Johannes Gutenberg-Universität Mainz, Mainz, Germany

🇩🇪

University Göttingen, Göttingen, Germany

🇩🇪

University Munich, Munich, Germany

Evaluation of Budesonide and How It Interacts With Antifungal Drugs in People With Gastrointestinal Graft-Versus-Host Disease

First Posted Date
2013-09-25
Last Posted Date
2021-03-12
Lead Sponsor
National Institutes of Health Clinical Center (CC)
Target Recruit Count
15
Registration Number
NCT01950507
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

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