Formoterol

Generic Name
Formoterol
Brand Names
Bevespi, Breyna, Breztri, Duaklir, Duaklir Genuair, Dulera, Foradil, Oxeze, Perforomist, Symbicort, Zenhale
Drug Type
Small Molecule
Chemical Formula
C19H24N2O4
CAS Number
73573-87-2
Unique Ingredient Identifier
5ZZ84GCW8B
Background

Formoterol is an inhaled beta-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers. A major clinical advantage of formoterol over other inhaled ...

Indication

Formoterol is indicated in various formulations for the treatment of asthma and COPD. For the treatment of COPD, formoterol is available as a single-entity inhalation solution, in combination with the long-acting muscarinic antagonists (LAMAs) aclidinium and glycopyrronium, and in combination with the corticosteroid budesonide. For the treatment of asthma, f...

Associated Conditions
Asthma, Bronchial Asthma, Bronchoconstriction, Chronic Obstructive Pulmonary Disease (COPD), Exercise-Induced Bronchospasm, Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Associated Therapies
Maintenance therapy

Efficacy, Safety, and Tolerability of Once Daily Indacaterol in Chronic Obstructive Pulmonary Disease (COPD) Using Formoterol Twice Daily as Active Control

First Posted Date
2006-10-27
Last Posted Date
2011-08-18
Lead Sponsor
Novartis
Target Recruit Count
1732
Registration Number
NCT00393458
Locations
🇬🇧

Novartis Investigator Site, Swansea, United Kingdom

🇪🇸

Novartis Investigative Site, Madrid, Spain

🇹🇷

Novartis, Istanbul, Turkey

SMILDA - Symbicort®Turbuhaler® Allergan Challenge Study in Allergic Patients With Mild Asthma

Phase 3
Completed
Conditions
First Posted Date
2006-02-08
Last Posted Date
2011-01-24
Lead Sponsor
AstraZeneca
Target Recruit Count
16
Registration Number
NCT00288379
Locations
🇸🇪

Research Site, Stockholm, Sweden

SHARE - Symbicort and Health Economics in a Real Life Evaluation

Phase 3
Completed
Conditions
First Posted Date
2005-12-01
Last Posted Date
2011-01-24
Lead Sponsor
AstraZeneca
Target Recruit Count
1970
Registration Number
NCT00259766
Locations
🇸🇪

Reseearch Site, Perstorp, Sweden

🇸🇪

Research Site, Örebro, Sweden

🇸🇪

Research site, Ödeshög, Sweden

To Evaluate the Long-term Safety of (R,R)-Formoterol in Subjects With COPD

First Posted Date
2003-07-09
Last Posted Date
2012-02-22
Lead Sponsor
Sumitomo Pharma America, Inc.
Target Recruit Count
799
Registration Number
NCT00064415
Locations
🇺🇸

Advances in Medicine, Rancho Mirage, California, United States

🇺🇸

Inland Clinical Research, Inc., Riverside, California, United States

🇺🇸

New Horizon Health Research, Atlanta, Georgia, United States

and more 85 locations
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