Formoterol

Generic Name
Formoterol
Brand Names
Bevespi, Breyna, Breztri, Duaklir, Duaklir Genuair, Dulera, Foradil, Oxeze, Perforomist, Symbicort, Zenhale
Drug Type
Small Molecule
Chemical Formula
C19H24N2O4
CAS Number
73573-87-2
Unique Ingredient Identifier
5ZZ84GCW8B
Background

Formoterol is an inhaled beta-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers. A major clinical advantage of formoterol over other inhaled ...

Indication

Formoterol is indicated in various formulations for the treatment of asthma and COPD. For the treatment of COPD, formoterol is available as a single-entity inhalation solution, in combination with the long-acting muscarinic antagonists (LAMAs) aclidinium and glycopyrronium, and in combination with the corticosteroid budesonide. For the treatment of asthma, f...

Associated Conditions
Asthma, Bronchial Asthma, Bronchoconstriction, Chronic Obstructive Pulmonary Disease (COPD), Exercise-Induced Bronchospasm, Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Associated Therapies
Maintenance therapy

Pharmacokinetic Interaction Study of Glycopyrrolate and Formoterol in Healthy Volunteers

First Posted Date
2011-07-20
Last Posted Date
2021-10-29
Lead Sponsor
Chiesi Farmaceutici S.p.A.
Target Recruit Count
44
Registration Number
NCT01398111
Locations
🇧🇪

Clinical Pharmacology Unit - SGS Life Science Services, Antwerpen, Lange Beeldekensstraat 267, Belgium

Efficacy of Inhaling Bronchodilator Medications in Chronic Obstructive Pulmonary Disease

First Posted Date
2011-07-12
Last Posted Date
2013-08-07
Lead Sponsor
Dartmouth-Hitchcock Medical Center
Target Recruit Count
20
Registration Number
NCT01391559
Locations
🇺🇸

Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States

Efficacy of Indacaterol 150 µg Versus Formoterol

First Posted Date
2011-06-21
Last Posted Date
2017-04-20
Lead Sponsor
Novartis Pharmaceuticals
Registration Number
NCT01377428

New Breath Actuated MDI Symbicort Compared to Symbicort pMDI and Budesonide pMDI for 12 Weeks Twice a Day

Phase 3
Completed
Conditions
Interventions
First Posted Date
2011-05-25
Last Posted Date
2014-03-11
Lead Sponsor
AstraZeneca
Target Recruit Count
214
Registration Number
NCT01360021
Locations
🇷🇺

Research Site, Moscow, Russia, Russian Federation

Blacks and Exacerbations on Long Acting Beta Agonists (LABA) vs. Tiotropium (BELT)

Phase 3
Completed
Conditions
Interventions
First Posted Date
2011-02-07
Last Posted Date
2018-03-30
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
1070
Registration Number
NCT01290874
Locations
🇺🇸

G.A. Carmichael F.H.C., Canton, Mississippi, United States

🇺🇸

Edward Waters College Medical Center (Mayo), Jacksonville, Florida, United States

🇺🇸

Northwestern University, Chicago, Illinois, United States

and more 10 locations

Use of Symbicort or Pulmicort to Treat Viral-mediated Asthma Exacerbations

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2010-10-11
Last Posted Date
2017-08-18
Lead Sponsor
Stanford University
Target Recruit Count
10
Registration Number
NCT01218399
Locations
🇺🇸

Stanford University School of Medicine, Stanford, California, United States

Effect of Formoterol on the Counterregulatory Hormonal Response to Hypoglycemia in Type 1 Diabetes.

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2010-09-03
Last Posted Date
2016-03-29
Lead Sponsor
Yale University
Target Recruit Count
14
Registration Number
NCT01194479
Locations
🇺🇸

Yale University School of Medicine, New Haven, Connecticut, United States

Evaluate Onset of Effect in Patients With Chronic Obstructive Pulmonary Disease (COPD) Treated With Formoterol Turbuhaler®

First Posted Date
2010-01-13
Last Posted Date
2012-10-25
Lead Sponsor
AstraZeneca
Target Recruit Count
109
Registration Number
NCT01048333
Locations
🇸🇪

Research Site, Lund, Sweden

Formoterol-HFA 3-month Study in Chronic Obstructive Pulmonary Disease (COPD) Patients

Phase 3
Completed
Conditions
Interventions
First Posted Date
2009-09-04
Last Posted Date
2011-12-13
Lead Sponsor
Chiesi Farmaceutici S.p.A.
Target Recruit Count
457
Registration Number
NCT00972140
Locations
🇵🇱

Prof. Iwona Graelewska Rzymowska, Lodz, Lódz, Poland

Efficacy of AZD3199 in Chronic Obstructive Pulmonary Disease (COPD) Patients

Phase 2
Completed
Conditions
Interventions
First Posted Date
2009-06-29
Last Posted Date
2014-02-17
Lead Sponsor
AstraZeneca
Target Recruit Count
329
Registration Number
NCT00929708
Locations
🇷🇺

Research Site, St. Petersburg, Russian Federation

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