Prasugrel
- Generic Name
- Prasugrel
- Brand Names
- Effient, Efient, Prasugrel Viatris (previously Prasugrel Mylan)
- Drug Type
- Small Molecule
- Chemical Formula
- C20H20FNO3S
- CAS Number
- 150322-43-3
- Unique Ingredient Identifier
- 34K66TBT99
- Background
Prasugrel, a thienopyridine derivative, is a platelet activation and aggregation inhibitor structurally and pharmacologically related to clopidogrel and ticlopidine. Similar to clopidogrel, prasugrel is a prodrug that requires enzymatic transformation in the liver to its active metabolite, R-138727. R-138727 irreversibly binds to P2Y12 type ADP receptors on ...
- Indication
用于心力衰竭、卒中、不稳定心绞痛等心脑血管疾病以及有急性冠状动脉综合征需要进行经皮冠脉介入术的患者。
- Associated Conditions
- Cardiovascular Events
- Associated Therapies
- -
TAXUS Libertē Post Approval Study
- Conditions
- First Posted Date
- 2009-10-19
- Last Posted Date
- 2015-08-07
- Lead Sponsor
- Boston Scientific Corporation
- Target Recruit Count
- 4199
- Registration Number
- NCT00997503
- Locations
- 🇺🇸
Torrance Memorial Medical Center, Torrance, California, United States
🇺🇸Advanced Cardiac Specialists, Mesa, Arizona, United States
🇺🇸NEA Baptist Memorial Hospital, Jonesboro, Arkansas, United States
Efficacy Study of Combined Prasugrel and Bivalirudin Versus Clopidogrel and Heparin in Myocardial Infarction
- Conditions
- Interventions
- First Posted Date
- 2009-09-14
- Last Posted Date
- 2014-01-07
- Lead Sponsor
- Deutsches Herzzentrum Muenchen
- Target Recruit Count
- 548
- Registration Number
- NCT00976092
- Locations
- 🇩🇪
Deutsches Herzzentrum Muenchen, Munich, Bavaria, Germany
🇩🇪Klinikum rechts der Isar, Technische Universitaet Muenchen, Munich, Bavaria, Germany
🇩🇪Herzzentrum der Segeberger Kliniken, Bad Segeberg, Germany
Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel (TRIGGER-PCI)
- Conditions
- Interventions
- First Posted Date
- 2009-05-29
- Last Posted Date
- 2012-06-08
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 423
- Registration Number
- NCT00910299
- Locations
- 🇩🇪
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Wuppertal, Germany
A Comparison of Antiplatelet Therapies in Asian Subjects With Acute Coronary Syndrome
- First Posted Date
- 2009-01-28
- Last Posted Date
- 2011-11-02
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 720
- Registration Number
- NCT00830960
- Locations
- 🇹🇭
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Chiang Mai, Thailand
A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects
- Conditions
- Interventions
- First Posted Date
- 2008-06-18
- Last Posted Date
- 2013-05-07
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 9326
- Registration Number
- NCT00699998
- Locations
- 🇬🇧
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Sunderland, United Kingdom
Third Optimizing Anti-Platelet Therapy in Diabetes MellitUS (OPTIMUS-3)
- Conditions
- Interventions
- First Posted Date
- 2008-03-24
- Last Posted Date
- 2010-02-23
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 35
- Registration Number
- NCT00642174
- Locations
- 🇺🇸
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Oklahoma City, Oklahoma, United States
The Effect on Blood Cells, Known as Platelets, Using Prasugrel vs Clopidogrel in Patients With the Heart Problem Acute Coronary Syndrome (ACS)
- First Posted Date
- 2006-10-11
- Last Posted Date
- 2010-09-16
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 56
- Registration Number
- NCT00385944
- Locations
- 🇫🇷
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Paris, France
Trial in Subjects Undergoing Cardiac Catheterization With Planned Percutaneous Coronary Intervention With Stenting
- Conditions
- Interventions
- First Posted Date
- 2006-07-28
- Last Posted Date
- 2010-08-31
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 201
- Registration Number
- NCT00357968
- Locations
- 🇮🇱
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Tel Hashomer, Israel
A Comparison of Prasugrel (CS-747) and Clopidogrel in Acute Coronary Syndrome Subjects Who Are to Undergo Percutaneous Coronary Intervention
- Conditions
- Interventions
- First Posted Date
- 2004-11-25
- Last Posted Date
- 2010-09-16
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 13619
- Registration Number
- NCT00097591
- Locations
- 🇺🇸
For more information regarding investigative sites for this trial, call 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri 9 AM - 5 PM Eastern Time (UTC/GMT - 5 hours, EST), Global Quintiles Study Line (1-866-615-4672) or speak with your physician, Indianapolis, Indiana, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.