Ursodeoxycholic acid
- Generic Name
- Ursodeoxycholic acid
- Brand Names
- Reltone, Urso, Urso Forte
- Drug Type
- Small Molecule
- Chemical Formula
- C24H40O4
- CAS Number
- 128-13-2
- Unique Ingredient Identifier
- 724L30Y2QR
- Background
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool. UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years. UDCA was first characterized in the bile of the Chinese black bear and is form...
- Indication
Ursodeoxycholic acid is indicated for the treatment of patients with primary biliary cholangitis.
It is used for the short-term treatment of radiolucent, noncalcified gallbladder stones in patients selected for elective cholecystectomy. It is also used to prevent gallstone formation in obese patients experiencing rapid weight loss.
- Associated Conditions
- Gallstones, Primary Biliary Cholangitis
- Associated Therapies
- -
Efficacy and Safety Study of TUDCA Compare UDCA to Treatment Chronic Cholestatic Liver Disease-PBC
- Conditions
- Interventions
- First Posted Date
- 2013-04-11
- Last Posted Date
- 2014-03-24
- Target Recruit Count
- 199
- Registration Number
- NCT01829698
- Locations
- 🇨🇳
Liver Research Center,Beijing Friendship Hospital, Beijing, Beijing, China
The Effect of Ursodeoxycholic Acid in Liver Functional Restoration of Patients With Obstructive Jaundice
- First Posted Date
- 2012-09-19
- Last Posted Date
- 2012-10-02
- Lead Sponsor
- University Clinical Centre of Kosova
- Target Recruit Count
- 54
- Registration Number
- NCT01688375
- Locations
- 🇷🇸
University clinical centre of Kosovo, Pristina, Kosovo, Serbia
🇷🇸University clinical centre of Kosovo, Department of general surgery, Pristina, Kosovo, Serbia
Ursodeoxycholic Acid in the Treatment of Intrahepatic Cholestasis of Pregnancy
- Conditions
- Interventions
- First Posted Date
- 2012-04-12
- Last Posted Date
- 2012-04-12
- Lead Sponsor
- Turku University Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT01576458
- Locations
- 🇫🇮
Turku University Hospital, Turku, Finland
Auto Transplant for High Risk or Relapsed Solid or CNS Tumors
- Conditions
- Interventions
- First Posted Date
- 2012-01-06
- Last Posted Date
- 2024-02-26
- Lead Sponsor
- Masonic Cancer Center, University of Minnesota
- Target Recruit Count
- 44
- Registration Number
- NCT01505569
- Locations
- 🇺🇸
Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States
Efficacy and Safety Study of Allogenic Mesenchymal Stem Cells for Patients With Refractory Primary Biliary Cirrhosis
- First Posted Date
- 2011-09-26
- Last Posted Date
- 2012-08-03
- Lead Sponsor
- Robert Chunhua Zhao, MD, PhD
- Target Recruit Count
- 20
- Registration Number
- NCT01440309
- Locations
- 🇨🇳
Peking Union Medical College Hospital, Beijing, China
Efficacy and Safety of Ursodeoxycholic Acid (UDCA) Added to the DPP-4 Inhibitor in People With Type 2 Diabetes and Chronic Liver Diseases
- Conditions
- Interventions
- First Posted Date
- 2011-04-18
- Last Posted Date
- 2011-04-18
- Lead Sponsor
- Kanazawa University
- Target Recruit Count
- 20
- Registration Number
- NCT01337440
- Locations
- 🇯🇵
Internal medicine, Kanazawa university hospital, Kanazawa, Ishikawa, Japan
Ursodeoxycholic Acid And Cholestasis Of Pregnancy
- Conditions
- Interventions
- First Posted Date
- 2010-10-22
- Last Posted Date
- 2016-05-12
- Lead Sponsor
- University of Bologna
- Registration Number
- NCT01226823
- Locations
- 🇮🇹
S.Orsola-Malpighi Hospital, Bologna, Italy
🇮🇹Divisione di Gastroenterologia, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy
🇮🇹UOC Ostetricia e Ginecologia, Ospedale Maggiore, Bologna, Italy
Preventive Effect of Enoxaparin, Pentoxifylline and Ursodeoxycholic Acid to Radiation Induced Liver Toxicity
- Conditions
- Interventions
- First Posted Date
- 2010-06-23
- Last Posted Date
- 2017-11-20
- Lead Sponsor
- University of Magdeburg
- Target Recruit Count
- 22
- Registration Number
- NCT01149304
- Locations
- 🇩🇪
Clinic for Radiology and Nuclear Medicine, Magdeburg, Sachsen-Anhalt, Germany
Cholestatic Drug-induced Liver Injury
- First Posted Date
- 2010-06-10
- Last Posted Date
- 2010-06-10
- Lead Sponsor
- Taipei Veterans General Hospital, Taiwan
- Target Recruit Count
- 180
- Registration Number
- NCT01141322
- Locations
- 🇨🇳
Taipei Veterans General Hospital, Taipei, Taiwan
Ursodiol in Treating Patients With Barrett Esophagus and Low-Grade Dysplasia
- Conditions
- Interventions
- First Posted Date
- 2010-04-01
- Last Posted Date
- 2017-12-19
- Lead Sponsor
- National Cancer Institute (NCI)
- Target Recruit Count
- 36
- Registration Number
- NCT01097304
- Locations
- 🇺🇸
Arizona Cancer Center-North Campus, Tucson, Arizona, United States
🇺🇸Southern Arizona Veterans Affairs Health Center, Tucson, Arizona, United States
🇺🇸University of Arizona Health Sciences Center, Tucson, Arizona, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.