Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA in 1951 and is available in a variety of forms including syrup form, regular tablets, effervescent tablets, injection, suppository, and other forms. Acetaminophen is often found combined with other drugs in more than 600 over the counter (OTC) allergy medications, cold medications, sleep medications, pain relievers, and other products. Confusion about dosing of this drug may be caused by the availability of different formulas, strengths, and dosage instructions for children of different ages. Due to the possibility of fatal overdose and liver failure associated with the incorrect use of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines while this drug is taken or prescribed.
Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA in 1951 and is available in a variety of forms including syrup form, regular tablets, effervescent tablets, injection, suppository, and other forms. Acetaminophen is often found combined with other drugs in more than 600 over the counter (OTC) allergy medications, cold medications, sleep medications, pain relievers, and other products. Confusion about dosing of this drug may be caused by the availability of different formulas, strengths, and dosage instructions for children of different ages. Due to the possibility of fatal overdose and liver failure associated with the incorrect use of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines while this drug is taken or prescribed.
In general, acetaminophen is used for the treatment of mild to moderate pain and reduction of fever. It is available over the counter in various forms, the most common being oral forms. Acetaminophen injection is indicated for the management of mild to moderate pain, the management of moderate to severe pain with adjunctive opioid analgesics, and the reduction of fever. Because of its low risk of causing allergic reactions, this drug can be administered in patients who are intolerant to salicylates and those with allergic tendencies, including bronchial asthmatics. Specific dosing guidelines should be followed when administering acetaminophen to children.
Acetaminophen, known internationally as paracetamol, is a globally recognized non-opioid analgesic and antipyretic agent.[1] It is widely available both over-the-counter (OTC) and as a prescription medication. The World Health Organization (WHO) recommends acetaminophen as a first-line therapeutic option for the management of mild to moderate pain.[1] Its primary clinical applications are the relief of pain and the reduction of fever, establishing it as a fundamental medication in symptomatic treatment for a diverse range of conditions.[3]
Acetaminophen is classified pharmacologically as a Small Molecule [User Query]. For precise identification in scientific and regulatory contexts, it is assigned the Chemical Abstracts Service (CAS) Number 103-90-2 and the DrugBank Accession Number DB00316 [User Query]. These identifiers are essential for accurate referencing in research, clinical databases, and chemical inventories.
Acetaminophen is one of the most frequently used medications for pain and fever relief in both the United States and Europe.[1] Its pervasive use is highlighted by its presence as an active ingredient in over 600 different OTC and prescription medicinal products, including standalone analgesics, fever reducers, sleep aids, and various combination formulations for cough, cold, and allergy symptoms.[5] The enduring clinical significance of acetaminophen is founded on its well-established efficacy for common ailments and a generally favorable safety profile when administered according to recommended dosing guidelines. This has solidified its position as an indispensable component of household medicine cabinets worldwide.[2]
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Title | Posted | Study ID | Phase | Status | Sponsor |
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2005/10/18 | Phase 3 | Completed | |||
2005/10/18 | Phase 4 | Completed | |||
2005/10/18 | Phase 4 | Completed | |||
2005/09/21 | Phase 3 | Completed | |||
2005/09/20 | Not Applicable | Terminated | |||
2005/09/16 | Not Applicable | Completed | University Hospital, Angers | ||
2005/09/16 | Phase 2 | Completed | |||
2005/09/16 | Phase 2 | Completed | |||
2005/09/09 | Phase 3 | Completed | |||
2005/09/07 | Phase 3 | Terminated |
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Product Name | Approval No. | Manufacturer | Dosage Form | Trade Name | Strength | Type | Status | Date | Import |
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国药准字H23021236 | 片剂(素片) | N/A | 0.3g | Chemical Drug | Approved | 2020/09/23 | Domestic | ||
国药准字H22020911 | 片剂 | N/A | 0.5g | Chemical Drug | Approved | 2020/03/23 | Domestic | ||
国药准字H43022131 | 片剂 | N/A | 0.1g | Chemical Drug | Approved | 2015/09/24 | Domestic | ||
国药准字H51020155 | 片剂 | N/A | 0.5g | Chemical Drug | Approved | 2021/02/10 | Domestic | ||
国药准字H51022964 | 片剂(素片,薄膜衣片) | N/A | 片剂(素片) | Chemical Drug | Approved | 2016/01/07 | Domestic | ||
国药准字H14021605 | 片剂 | N/A | 0.3g | Chemical Drug | Approved | 2020/08/27 | Domestic | ||
国药准字H43022132 | 片剂 | N/A | 0.5g | Chemical Drug | Approved | 2022/12/19 | Domestic | ||
国药准字H37020067 | 片剂 | N/A | 0.3g | Chemical Drug | Approved | 2015/06/23 | Domestic | ||
国药准字H13022470 | 片剂 | N/A | 0.3g | Chemical Drug | Approved | 2020/07/22 | Domestic | ||
国药准字H14021337 | 片剂 | N/A | 0.5g | Chemical Drug | Approved | 2020/04/20 | Domestic |
Product Name | Registration Code | Company | Category | Sale Type | Reg. Date |
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HK-27985 | unicorn laboratories o/b american unicorn laboratories limited | Part 2 Poison | OTC | 1986/11/28 | |
HK-50245 | unicorn laboratories o/b american unicorn laboratories limited | Part 2 Poison | OTC | 2002/10/18 | |
HK-61400 | Evercare Pharmaceutical Company Limited | Part 2 Poison | OTC | 2012/09/07 | |
HK-31209 | Haleon Hong Kong Limited | Part 2 Poison | OTC | 1988/11/24 | |
HK-46476 | unicorn laboratories o/b american unicorn laboratories limited | Part 2 Poison | OTC | 2000/06/30 | |
HK-46478 | unicorn laboratories o/b american unicorn laboratories limited | Part 2 Poison | OTC | 2000/06/30 | |
HK-06328 | unicorn laboratories o/b american unicorn laboratories limited | Part 2 Poison | OTC | 1979/05/25 | |
HK-43594 | Haleon Hong Kong Limited | Part 2 Poison | OTC | 1998/09/05 | |
HK-64868 | Evercare Pharmaceutical Company Limited | Part 2 Poison | OTC | 2017/01/03 | |
HK-50183 | unicorn laboratories o/b american unicorn laboratories limited | Part 2 Poison | OTC | 2002/09/30 |
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