Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Preoperative Nebulized Dexmedetomidine on Hemodynamic Changes in Laparoscopic Bariatric Surgery.
- Conditions
- Interventions
- First Posted Date
- 2023-08-28
- Last Posted Date
- 2023-08-31
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 90
- Registration Number
- NCT06014359
- Locations
- 🇪🇬
Tanta University, Tanta, ElGharbia, Egypt
CSF Metabolomics and Glymphatic Function in Patients Receiving VP- Shunt Surgery.
- First Posted Date
- 2023-08-22
- Last Posted Date
- 2023-08-22
- Lead Sponsor
- Chang Gung Memorial Hospital
- Target Recruit Count
- 48
- Registration Number
- NCT06005363
- Locations
- 🇨🇳
Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan
Single Shot Intrathecal Analgesia in Vaginal Delivery
- Conditions
- Interventions
- First Posted Date
- 2023-08-21
- Last Posted Date
- 2023-08-21
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 75
- Registration Number
- NCT05998551
- Locations
- 🇪🇬
Ainshams University, Cairo, Egypt
Evaluation of the Postoperative Agitation Prevention and Analgesic Efficacy of Perioperative Dexmedetomidine Infusion in a Pediatric Patient Group to Undergo Tonsillectomy and Adenoidectomy
- Conditions
- Interventions
- First Posted Date
- 2023-08-14
- Last Posted Date
- 2023-11-08
- Lead Sponsor
- Burak Omur
- Target Recruit Count
- 80
- Registration Number
- NCT05986942
- Locations
- 🇹🇷
Istanbul Medipol University, Istanbul, Turkey
Intraperitoneal Dexamethasone, Dexmedetomidine, and Dexamethasone-Dexmedetomidine Combination on Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
- First Posted Date
- 2023-08-14
- Last Posted Date
- 2024-07-31
- Lead Sponsor
- Al-Azhar University
- Target Recruit Count
- 120
- Registration Number
- NCT05988671
- Locations
- 🇪🇬
Neveen Kohaf, Tanta, Egypt
🇪🇬Haney Baumey, Banhā, Egypt
Effect of Dexmedetomidine on the Quality of Recovery in Parturients Undergoing Elective Caesarean Sections
- First Posted Date
- 2023-08-14
- Last Posted Date
- 2024-11-11
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 141
- Registration Number
- NCT05991466
- Locations
- 🇪🇬
Faculty of Medicine, Cairo University, Cairo, Egypt
Comparison of Efficacy of Bupivacaine in Supraclavicular Block With or Without Dexmedetomidine
- First Posted Date
- 2023-08-14
- Last Posted Date
- 2023-08-14
- Lead Sponsor
- Sindh Institute of Urology and Transplantation
- Target Recruit Count
- 108
- Registration Number
- NCT05991375
- Locations
- 🇵🇰
Syed Muhammad Abbas, Karachi, Sindh, Pakistan
Dexmedetomidine Versus Dexmedetomidine With Ketamine in Mechanically Ventilated ARDS Patients
- Conditions
- Interventions
- First Posted Date
- 2023-07-19
- Last Posted Date
- 2023-08-01
- Lead Sponsor
- Benha University
- Target Recruit Count
- 60
- Registration Number
- NCT05951387
- Locations
- 🇪🇬
Benha university, Banhā, Qalubia, Egypt
Different Administration Routes of Dexmedetomidine on Postoperative Delirium
- Conditions
- Interventions
- First Posted Date
- 2023-07-19
- Last Posted Date
- 2023-07-19
- Target Recruit Count
- 120
- Registration Number
- NCT05952050
- Locations
- 🇨🇳
Weitao Chen, Zhongshan, Guangdong, China
Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality
- Conditions
- Interventions
- First Posted Date
- 2023-07-18
- Last Posted Date
- 2023-11-24
- Lead Sponsor
- Peking University First Hospital
- Target Recruit Count
- 154
- Registration Number
- NCT05950646
- Locations
- 🇨🇳
Beijing Hospital, Beijing, Beijing, China
🇨🇳Peking University First Hospital, Beijing, Beijing, China
Drug Development Updates
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