Overview
Carbon dioxide is a colorless, odorless gas vital to life on Earth. This naturally occurring chemical compound is composed of a carbon atom covalently double bonded to two oxygen atoms. Medical Carbon Dioxide is a liquefied medicinal gas, supplied in cylinders filled to a high pressure. Medical Carbon Dioxide may be used in different situations, e.g. during bodily investigations, to inflate body cavities during surgery (such as key-hole surgery), and in solid form (dry ice) for freezing of tissue and removal of warts.
Indication
Carbon dioxide is commonly used as an insufflation gas for minimal invasive surgery (laparoscopy, endoscopy, and arthroscopy) to enlarge and stabilize body cavities to provide better visibility of the surgical area. It has been used also in cryotherapy and as respiratory stimulant before and after anesthesia. It could be used also in expansion of blood vessels if required, to increase carbon dioxide level after rapid breathing, and to stimulate breathing after a period of nonbreathing.
Associated Conditions
- Hypoplastic Left Heart Syndrome (HLHS)
- Laryngeal Injuries
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2023/03/09 | Not Applicable | Recruiting | |||
2020/05/28 | Not Applicable | Recruiting | |||
2017/08/28 | Not Applicable | Completed | Kaiser Clinic and Hospital | ||
2016/11/08 | Not Applicable | Completed | |||
2015/06/16 | Phase 1 | Completed | |||
2014/04/14 | Phase 2 | Completed |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| AIRGAS NOR PAC INC | 57472-004 | RESPIRATORY (INHALATION) | 992 mL in 1 L | 5/10/2011 | |
| Linde Gas & Equipment Inc. | 25373-004 | RESPIRATORY (INHALATION) | 99 L in 100 L | 11/15/2017 | |
| Airgas Usa, LLC | 11054-130 | RESPIRATORY (INHALATION) | 992 mL in 1 L | 1/26/2022 | |
| AGL Inhalation Therapy Co. | 17575-104 | RESPIRATORY (INHALATION) | 990 mL in 1 L | 10/6/2023 | |
| Roberts Oxygen Company, Inc. | 46123-121 | RESPIRATORY (INHALATION) | 100 mL in 1 L | 11/19/2020 | |
| Medical-Technical Gases, Inc. | 10736-009 | RESPIRATORY (INHALATION) | 5 mL in 1 L | 12/22/2012 | |
| Medical-Technical Gases, Inc. | 10736-010 | RESPIRATORY (INHALATION) | 5 mL in 1 L | 12/22/2012 | |
| Medical-Technical Gases, Inc. | 10736-012 | RESPIRATORY (INHALATION) | 10 mL in 1 L | 12/22/2012 | |
| AIRGAS THERAPEUTICS LLC | 82605-001 | RESPIRATORY (INHALATION) | 1 g in 1 g | 10/6/2023 | |
| Red Ball Oxygen Co., Inc. | 46362-004 | RESPIRATORY (INHALATION) | 990 mL in 1 L | 10/18/2023 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| CARBON DIOXIDE, MEDICAL | 34463 | Medicine | A | 1/2/1992 | |
| Coregas Pty Ltd medical carbon dioxide 100% v/v gas in gas cylinder | 27190 | Medicine | A | 10/21/1991 | |
| CARBOGEN 5% CARBON DIOXIDE IN OXYGEN MIXTURE | 34469 | Medicine | A | 1/2/1992 | |
| CARBANOX medical carbon dioxide 5% v/v and oxygen 95% v/v gas in gas cylinder | 27180 | Medicine | A | 10/21/1991 | |
| MEDICAL SPECIAL GAS MIXTURES | 34465 | Medicine | A | 1/2/1992 | |
| AIR LIQUIDE AUSTRALIA LIMITED Carbon Dioxide 100% v/v Gas Medicinal | 32742 | Medicine | A | 11/1/1991 |
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