Azithromycin

Generic Name
Azithromycin
Brand Names
Azasite, Zithromax, Zmax
Drug Type
Small Molecule
Chemical Formula
C38H72N2O12
CAS Number
83905-01-5
Unique Ingredient Identifier
J2KLZ20U1M
Background

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 .
...

Indication

Azithromycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria in order to prevent the development antimicrobial resistance and maintain the efficacy of azithromycin .
...

Associated Conditions
Acute Bacterial Sinusitis (ABS), Acute Otitis Media (AOM), Acute bacterial exacerbation of COPD caused by Haemophilus Influenza Infections, Moraxella Catarrhalis Infection, Streptococcus Pneumoniae Infections, Bacterial Conjunctivitis, Bacterial Sinusitis, Cervicitis, Chancroid, Community Acquired Pneumonia (CAP), Genital Ulcer Disease (GUD), Pelvic Inflammatory Disease (PID), Pharyngitis, Streptococcal Pharyngitis, Tonsillitis bacterial, Tonsillitis streptococcal, Traveler's Diarrhea, Uncomplicated Skin and Skin Structure Infections, Urethritis
Associated Therapies
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Trial Comparing Ceftriaxone Plus Azithromycin Versus Ceftriaxone for the Treatment of Gonorrhea

Phase 4
Completed
Conditions
Interventions
First Posted Date
2021-08-30
Last Posted Date
2024-08-02
Lead Sponsor
Institute of Tropical Medicine, Belgium
Target Recruit Count
42
Registration Number
NCT05027516
Locations
🇧🇪

Institute of Tropical Medicine, Antwerpen, Belgium

Hypertonic Saline for MAC

First Posted Date
2021-06-10
Last Posted Date
2023-12-19
Lead Sponsor
Oregon Health and Science University
Target Recruit Count
50
Registration Number
NCT04921943
Locations
🇺🇸

NYU Langone Health, New York, New York, United States

🇨🇦

University Health Network, Toronto, Ontario, Canada

🇺🇸

Oregon Health & Science University, Portland, Oregon, United States

Experimental Human Infection With Neisseria Gonorrhoeae (LptA Trial)

First Posted Date
2021-05-03
Last Posted Date
2021-12-02
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
16
Registration Number
NCT04870138
Locations
🇺🇸

University of North Carolina Health Care - Infectious Diseases, Chapel Hill, North Carolina, United States

EAT-DUTA AndroCoV Trial

First Posted Date
2021-01-28
Last Posted Date
2021-01-28
Lead Sponsor
Corpometria Institute
Target Recruit Count
138
Registration Number
NCT04729491
Locations
🇧🇷

Corpometria Institute, Brasília, DF, Brazil

Infant Mortality Reduction by the Mass Administration of Azithromycin

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2021-01-20
Last Posted Date
2023-06-13
Lead Sponsor
University of California, San Francisco
Target Recruit Count
694400
Registration Number
NCT04716712
Locations
🇧🇫

Helen Keller International, Ouagadougou, Burkina Faso

🇺🇸

University of California, San Francisco, San Francisco, California, United States

🇧🇫

Centre de Recherche en Sante de Nouna, Nouna, Burkina Faso

The Effect of Azithromycin Use on Conduction System of Heart in COVID-19 Positive Children

First Posted Date
2021-01-07
Last Posted Date
2021-01-07
Lead Sponsor
Kayseri City Hospital
Target Recruit Count
105
Registration Number
NCT04699097
Locations
🇹🇷

Süleyman Sunkak, Kayseri, In The USA Or Canada, Please Select..., Turkey

Validation of Patient Reported Outcome Measures in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex

First Posted Date
2020-12-21
Last Posted Date
2024-06-28
Lead Sponsor
Insmed Incorporated
Target Recruit Count
99
Registration Number
NCT04677543
Locations
🇪🇸

ESP002, Barcelona, Spain

🇪🇸

ESP004, Madrid, Spain

🇪🇸

ESP003, Barcelona, Spain

and more 59 locations

Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex

First Posted Date
2020-12-21
Last Posted Date
2024-11-25
Lead Sponsor
Insmed Incorporated
Target Recruit Count
425
Registration Number
NCT04677569
Locations
🇺🇸

USA014, Saint Petersburg, Florida, United States

🇺🇸

USA084, Sebastian, Florida, United States

🇺🇸

USA067, Tampa, Florida, United States

and more 159 locations

AZithromycin Therapy in Preschoolers with a Severe Wheezing Episode Diagnosed At the Emergency Department

Phase 3
Active, not recruiting
Conditions
Interventions
First Posted Date
2020-12-16
Last Posted Date
2024-12-16
Lead Sponsor
University of Arizona
Target Recruit Count
1476
Registration Number
NCT04669288
Locations
🇺🇸

Children's Healthcare of Atlanta, Emory University, Atlanta, Georgia, United States

🇺🇸

Boston Children's Hospital, Boston, Massachusetts, United States

🇺🇸

Children's Hospital of New York Medical Center, New York, New York, United States

and more 5 locations

Clarithromycin Versus Azithromycin in Treatment of Mild COVID-19 Infection

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2020-11-10
Last Posted Date
2020-11-10
Lead Sponsor
South Valley University
Target Recruit Count
300
Registration Number
NCT04622891
Locations
🇪🇬

south-Vally University faculty of medicine, Qena, Egypt

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