MedPath

Amprenavir

Generic Name
Amprenavir
Drug Type
Small Molecule
Chemical Formula
C25H35N3O6S
CAS Number
161814-49-9
Unique Ingredient Identifier
5S0W860XNR
Background

Amprenavir is a protease inhibitor used to treat HIV infection.

Indication

用于高效抗逆转录病毒疗法(HAART)的组成药物。

A Phase I Trial to Evaluate the Safety, Pharmacokinetics and Antiviral Activity of 141W94 After Multiple Dosing in Patients With HIV Infection

Phase 1
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Glaxo Wellcome
Target Recruit Count
60
Registration Number
NCT00002183
Locations
🇺🇸

UCSD, San Diego, California, United States

🇺🇸

Univ of Colorado Health Sciences Ctr, Denver, Colorado, United States

🇺🇸

AIDS Research Consortium of Atlanta, Atlanta, Georgia, United States

A Study of Amprenavir in HIV-Infected Patients

Not Applicable
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Glaxo Wellcome
Registration Number
NCT00002405
Locations
🇺🇸

Glaxo Wellcome Inc, Research Triangle Park, North Carolina, United States

Safety and Effectiveness of Giving Two Nucleoside Reverse Transcriptase Inhibitors Alone or in Combination With 141W94 to HIV-Infected Children Who Have Never Received Protease Inhibitors

Phase 3
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Glaxo Wellcome
Target Recruit Count
210
Registration Number
NCT00002193
Locations
🇺🇸

Children's Diagnostic Treatment Ctr, Fort Lauderdale, Florida, United States

🇺🇸

Saint Jude Children's Hosp / Dept of Infect Diseases, Memphis, Tennessee, United States

A Study of a Combination of Four Drugs in Patients With Recent HIV Infection

Phase 2
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Glaxo Wellcome
Target Recruit Count
30
Registration Number
NCT00002233
Locations
🇺🇸

Aaron Diamond AIDS Rsch Ctr / Rockefeller Univ, New York, New York, United States

🇺🇸

Miriam Hosp / Family Healthcare Ctr at SSTAR, Providence, Rhode Island, United States

A Study to Compare Three Doses of T-20 When Given in Combination With Abacavir, Amprenavir, Ritonavir, and Efavirenz to HIV-Infected Adults

Phase 2
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2005-11-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
68
Registration Number
NCT00002239
Locations
🇺🇸

UCLA Care Ctr, Los Angeles, California, United States

🇺🇸

AIDS Research Consortium of Atlanta, Atlanta, Georgia, United States

🇺🇸

Pennsylvania Oncology and Hematology Associates, Philadelphia, Pennsylvania, United States

and more 16 locations

A Comparison of Two Multi-Drug Therapies in HIV-Infected Patients Who Have Never Received Anti-HIV Treatment

Not Applicable
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Glaxo Wellcome
Registration Number
NCT00002216
Locations
🇺🇸

Anderson Clinical Research, Pittsburgh, Pennsylvania, United States

A Study of Three Anti-HIV Drug Combinations in Patients Who Have Taken Amprenavir

Phase 2
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
94
Registration Number
NCT00001095
Locations
🇺🇸

St Louis Regional Hosp / St Louis Regional Med Ctr, Saint Louis, Missouri, United States

🇺🇸

Univ of North Carolina, Chapel Hill, North Carolina, United States

🇺🇸

Univ of Southern California / LA County USC Med Ctr, Los Angeles, California, United States

and more 9 locations

Continued Antiretroviral Therapy With Abacavir, Amprenavir and Efavirenz

Phase 2
Completed
Conditions
HIV Infection
First Posted Date
1999-11-04
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
25
Registration Number
NCT00001758
Locations
🇺🇸

National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland, United States

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