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Platinum

Generic Name
Platinum
Drug Type
Small Molecule
Chemical Formula
Pt
CAS Number
7440-06-4
Unique Ingredient Identifier
49DFR088MY
Background

Platinum is under investigation for the treatment of Metastatic Breast Cancer, Non-small Cell Lung Cancer, Gastric Large Cell Neuroendocrine Carcinoma, Colorectal Large Cell Neuroendocrine Carcinoma, and Pancreatic Large Cell Neuroendocrine Carcinoma, among others. Platinum has been investigated for the treatment and supportive care of Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Primary Cancer, Non Small Cell Lung Cancer, and Primary Peritoneal Carcinoma, among others.

Trial of BMS-986012 in Combination With Platinum and Etoposide

Phase 1
Active, not recruiting
Conditions
Small Cell Lung Cancer
Interventions
First Posted Date
2016-06-28
Last Posted Date
2024-05-23
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
12
Registration Number
NCT02815592
Locations
🇪🇸

Local Institution - 0002, Barcelona, Spain

🇪🇸

Local Institution - 0004, Madrid, Spain

🇪🇸

Local Institution - 0010, Malaga, Spain

and more 1 locations

Nivolumab in Combination With Ipilimumab (Part 1); Nivolumab Plus Ipilimumab in Combination With Chemotherapy (Part 2) as First Line Therapy in Stage IV Non-Small Cell Lung Cancer

Phase 2
Completed
Conditions
Non-Small-Cell Lung Cancer
Interventions
Biological: Nivolumab
Biological: Ipilimumab
First Posted Date
2016-01-20
Last Posted Date
2023-04-05
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
324
Registration Number
NCT02659059
Locations
🇺🇸

Local Institution - 0010, Mineola, New York, United States

🇨🇦

Local Institution - 0022, Kingston, Ontario, Canada

🇺🇸

Local Institution - 0015, Lincoln, Nebraska, United States

and more 29 locations

Recombinant Human Endostatin (EndostarTM) Injection in Treatment of Recurrent Metastatic Breast Cancer

Phase 2
Conditions
Breast Neoplasms
Interventions
First Posted Date
2015-07-03
Last Posted Date
2017-07-17
Lead Sponsor
Xinjiang Medical University
Target Recruit Count
120
Registration Number
NCT02489409
Locations
🇨🇳

Third Affiliated Hospital of Xinjiang Medical University, Urumchi, Xinjiang, China

SAFIR02_Breast - Efficacy of Genome Analysis as a Therapeutic Decision Tool for Patients With Metastatic Breast Cancer

First Posted Date
2014-11-24
Last Posted Date
2025-01-15
Lead Sponsor
UNICANCER
Target Recruit Count
1460
Registration Number
NCT02299999
Locations
🇫🇷

Hopitaux Universitaire de Strasbourg - Hopital Civil, Strasbourg, France

🇫🇷

Institut Claudius Regaud, Toulouse, France

🇫🇷

Hopitaux Du Leman, Thonon-les-Bains, France

and more 21 locations

Safety Study of Combining Ultrasound Microbubbles and Chemotherapy to Treat Malignant Neoplasms of Digestive System

Phase 1
Conditions
Gastrointestinal Neoplasms
Interventions
Device: ultrasonic microbubbles
First Posted Date
2014-09-08
Last Posted Date
2015-07-24
Lead Sponsor
Peking University Cancer Hospital & Institute
Target Recruit Count
18
Registration Number
NCT02233205
Locations
🇨🇳

Beijing Cancer Hospital, Beijing, China

Intercalated Combination of Chemotherapy and Tyrosine Kinase Inhibitors as First-line Treatment for Patients With Non-Small-Cell Lung Cancer

First Posted Date
2014-01-09
Last Posted Date
2016-03-29
Lead Sponsor
Qilu Hospital of Shandong University
Target Recruit Count
250
Registration Number
NCT02031601
Locations
🇨🇳

Yu Li, Jinan, Shandong, China

An Exploratory Study of OCZ103-OS in Combination With Standard of Care in Stage IV Non-Small Cell Lung Cancer (NSCLC) Patients

Phase 2
Completed
Conditions
Non-small Cell Lung Cancer
Interventions
First Posted Date
2013-05-01
Last Posted Date
2014-10-21
Lead Sponsor
Oncozyme Pharma Inc.
Target Recruit Count
25
Registration Number
NCT01844791
Locations
🇵🇱

Ewa Kalinka-Warzocha, Lodz, Poland

An Observational Study of CPT-11 Plus Platinum Analogues Regimens and UGT1A1 Genotypes in Solid Tumors

Completed
Conditions
Cervical Cancer
Non-small Cell Lung Cancer
Ovarian Cancer
Gastric Cancer (Inoperable and Recurrent)
Small Cell Lung Cancer
Interventions
First Posted Date
2009-12-29
Last Posted Date
2019-05-23
Lead Sponsor
Daiichi Sankyo Co., Ltd.
Target Recruit Count
321
Registration Number
NCT01040312
Locations
🇯🇵

Department of Obstetrics and Gynecology, National Defense Medical College Hospital, Tokorozawa, Japan

A Study of Tarceva (Erlotinib) or Placebo in Combination With Platinum-Based Therapy as First Line Treatment in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer

Phase 3
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2009-04-20
Last Posted Date
2015-12-14
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
451
Registration Number
NCT00883779

Randomized Gefitinib Trial

Phase 3
Completed
Conditions
Non Small Cell Lung Cancer
Interventions
First Posted Date
2008-12-11
Last Posted Date
2012-04-23
Lead Sponsor
Fondazione Humanitas per la Ricerca
Target Recruit Count
1
Registration Number
NCT00807066
Locations
🇮🇹

Fondazione Humanitas per la Ricerca, Rozzano, Milan, Italy

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