Metoclopramide
- Generic Name
- Metoclopramide
- Brand Names
- Gimoti, Reglan
- Drug Type
- Small Molecule
- Chemical Formula
- C14H22ClN3O2
- CAS Number
- 364-62-5
- Unique Ingredient Identifier
- L4YEB44I46
- Background
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GER...
- Indication
Metoclopramide in the oral tablet form is used for symptomatic treatment of both acute and recurrent diabetic gastroparesis, in addition to the treatment of gastroesophageal reflux disease (GERD) in patients who have failed to respond to traditional therapy. A nasal spray formulation is also indicated to treat adults with acute, recurrent diabetic gastropare...
- Associated Conditions
- Chemotherapy-Induced Nausea and Vomiting, Diabetic Gastroparesis, Dyspepsia, Flatulence, Gastroesophageal Reflux, Gastroparesis, Hiccups, Hyperacidity, Migraine, Nausea and vomiting, Post Operative Nausea and Vomiting (PONV), Radiation-Induced Nausea and Vomiting, Acute, recurrent Diabetic Gastroparesis, Gastric bezoar
- Associated Therapies
- Facilitation of small bowel intubation therapy, Gastric emptying for radiologic procedures
Broadening Antiemetics Research by Comparing the Effectiveness of Fosaprepitant and Metoclopramide
- Conditions
- Interventions
- First Posted Date
- 2024-12-18
- Last Posted Date
- 2024-12-18
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 212
- Registration Number
- NCT06740812
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
The Efficacy of B6 and Metoclopramide Combination in Comparison With the Other Antiemetics
- Conditions
- Interventions
- First Posted Date
- 2024-04-30
- Last Posted Date
- 2024-04-30
- Lead Sponsor
- University of Baghdad
- Target Recruit Count
- 250
- Registration Number
- NCT06390787
- Locations
- 🇮🇶
Al-Nassiryah Teaching Hospital, Nasiriyah, Thi Qar, Iraq
NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.
- Conditions
- Interventions
- Drug: [68Ga]Ga-PSMA-11Drug: [68Ga]GA-DOTA-TATEDrug: [68Ga]Ga-NeoBDrug: [177Lu]Lu-PSMA-617Drug: [177Lu]Lu-DOTA-TATEDrug: [177Lu]Lu-NeoBDrug: Gonadotropin-releasing hormone (GnRH) analoguesDrug: L-Lysine HCl-L-Arginine HCl, 2.5 %,Drug: GnRH antagonistsDrug: Antiemetics & antinauseantsDrug: Metoclopramide
- First Posted Date
- 2024-04-23
- Last Posted Date
- 2024-12-04
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 36
- Registration Number
- NCT06379217
- Locations
- 🇺🇸
Nebraska Cancer Specialists, Omaha, Nebraska, United States
🇪🇸Novartis Investigative Site, Hospitalet de LLobregat, Catalunya, Spain
Usefulness of Metoclopramide to Improve Endoscopic Visualization in Upper Gastrointestinal Bleeding
- Conditions
- Interventions
- First Posted Date
- 2024-03-07
- Last Posted Date
- 2024-10-09
- Lead Sponsor
- Universidad Autonoma de Nuevo Leon
- Target Recruit Count
- 50
- Registration Number
- NCT06297954
- Locations
- 🇲🇽
Hospital Universitario Dr. José Eleuterio González, UANL, Monterrey, Nuevo León, Mexico
Evaluating the Effect of Intravenous Dexamethasone on the Duration of Spinal Anesthesia After Cesarean Delivery
- Conditions
- Interventions
- First Posted Date
- 2023-02-16
- Last Posted Date
- 2024-07-08
- Lead Sponsor
- IWK Health Centre
- Target Recruit Count
- 192
- Registration Number
- NCT05731960
- Locations
- 🇨🇦
IWK Health Centre, Halifax, Nova Scotia, Canada
Metoclopramide on Gastric Emptying in Mechanically Ventilated Patients
- Conditions
- Interventions
- First Posted Date
- 2022-12-07
- Last Posted Date
- 2023-06-22
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 80
- Registration Number
- NCT05641051
- Locations
- 🇪🇬
Tanta University Hospitals, Tanta, ElGharbiaa, Egypt
Midodrine for Prophylaxis Against Post Spinal Hypotension in Elderly Population
- Conditions
- Interventions
- First Posted Date
- 2022-09-22
- Last Posted Date
- 2023-09-15
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 58
- Registration Number
- NCT05548985
- Locations
- 🇪🇬
Cairo University, Cairo, Egypt
Efficacy of Three Antiemetics in Preventing Nausea and Vomiting
- Conditions
- Interventions
- First Posted Date
- 2022-09-09
- Last Posted Date
- 2024-04-02
- Target Recruit Count
- 200
- Registration Number
- NCT05533281
- Locations
- 🇨🇳
The Second Affiliated Hospital, Chongqing Medical University, Chongqing, Chongqing, China
The Effect of Prucalopride on Gastric Emptying in Intensive Care Unit Patients
- Conditions
- Interventions
- First Posted Date
- 2022-08-11
- Last Posted Date
- 2024-04-12
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 70
- Registration Number
- NCT05496179
- Locations
- 🇪🇬
Kasr Al Ainy Hospital, Cairo, Egypt
Metoclopramide Versus Hyoscine Butylbromide in Shortening Duration of First Stage of Labour
- First Posted Date
- 2022-02-03
- Last Posted Date
- 2022-02-03
- Lead Sponsor
- Uwakwe Emmanuel Chijioke
- Target Recruit Count
- 150
- Registration Number
- NCT05222646
- Locations
- 🇳🇬
AEFUTHA, Abakaliki, Ebonyi, Nigeria
Drug Development Updates
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