Metoclopramide
- Generic Name
- Metoclopramide
- Brand Names
- Gimoti, Reglan
- Drug Type
- Small Molecule
- Chemical Formula
- C14H22ClN3O2
- CAS Number
- 364-62-5
- Unique Ingredient Identifier
- L4YEB44I46
- Background
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GER...
- Indication
Metoclopramide in the oral tablet form is used for symptomatic treatment of both acute and recurrent diabetic gastroparesis, in addition to the treatment of gastroesophageal reflux disease (GERD) in patients who have failed to respond to traditional therapy. A nasal spray formulation is also indicated to treat adults with acute, recurrent diabetic gastropare...
- Associated Conditions
- Chemotherapy-Induced Nausea and Vomiting, Diabetic Gastroparesis, Dyspepsia, Flatulence, Gastroesophageal Reflux, Gastroparesis, Hiccups, Hyperacidity, Migraine, Nausea and vomiting, Post Operative Nausea and Vomiting (PONV), Radiation-Induced Nausea and Vomiting, Acute, recurrent Diabetic Gastroparesis, Gastric bezoar
- Associated Therapies
- Facilitation of small bowel intubation therapy, Gastric emptying for radiologic procedures
A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance
- First Posted Date
- 2013-09-30
- Last Posted Date
- 2020-02-18
- Lead Sponsor
- Takeda
- Target Recruit Count
- 13
- Registration Number
- NCT01953081
- Locations
- 🇦🇺
Royal Adelaide Hospital, Adelaide, South Australia, Australia
Use of an Antiemetic to Shorten the Length of Labor in Nulliparous Women
- Conditions
- Interventions
- First Posted Date
- 2013-09-09
- Last Posted Date
- 2017-03-10
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 250
- Registration Number
- NCT01937234
- Locations
- 🇸🇦
Labor and delivery ward of Armed Forces Hospital, Southern Region., Khamis Mushait, Saudi Arabia
Intrathecal Levobupivacaine With Opioids for Caesarean Section
- First Posted Date
- 2013-05-21
- Last Posted Date
- 2013-05-21
- Lead Sponsor
- Baskent University
- Target Recruit Count
- 93
- Registration Number
- NCT01858090
- Locations
- 🇹🇷
Baskent University School of Medicine Adana Teaching and Research Hospital, Adana, Turkey
Ultrasound-guided Blocks for Ambulatory Knee Arthroscopy
- First Posted Date
- 2013-04-23
- Last Posted Date
- 2013-11-06
- Lead Sponsor
- Jens Borglum Neimann
- Target Recruit Count
- 60
- Registration Number
- NCT01837394
- Locations
- 🇩🇰
Department of Anesthesiology, Bispebjerg Hospital, Copenhagen, Denmark
Diphenhydramine for Acute Migraine
- Conditions
- Interventions
- First Posted Date
- 2013-04-08
- Last Posted Date
- 2018-07-31
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 208
- Registration Number
- NCT01825941
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Prophylactic Subhypnotic Propofol for Nausea and Vomiting During for Cesarean Section Under Subarachnoid Anesthesia.
- First Posted Date
- 2013-02-01
- Last Posted Date
- 2014-12-16
- Lead Sponsor
- G. d'Annunzio University
- Target Recruit Count
- 112
- Registration Number
- NCT01781377
- Locations
- 🇮🇹
A.O. SS.ma Annunziata, Chieti, Italy
Study to Evaluate the Efficacy of Oral Dissolving Metoclopramide Before Video Capsule Endoscopy
- First Posted Date
- 2012-06-29
- Last Posted Date
- 2023-04-11
- Lead Sponsor
- Winthrop University Hospital
- Target Recruit Count
- 6
- Registration Number
- NCT01631994
- Locations
- 🇺🇸
Winthrop University Hospital, Mineola, New York, United States
Study of Metoclopramide in Small Bowel Capsule Endoscopy
- Conditions
- Interventions
- First Posted Date
- 2012-06-28
- Last Posted Date
- 2014-02-27
- Lead Sponsor
- Ascension Health
- Target Recruit Count
- 5
- Registration Number
- NCT01630109
- Locations
- 🇺🇸
Genesys Regional Medical Center, Grand Blanc, Michigan, United States
Intravenous Ketorolac and Metoclopramide for Pediatric Migraine in the Emergency Department
- Conditions
- Interventions
- First Posted Date
- 2012-05-10
- Last Posted Date
- 2015-01-26
- Lead Sponsor
- University of Alberta
- Target Recruit Count
- 56
- Registration Number
- NCT01596166
- Locations
- 🇨🇦
Stollery Children's Hospital, Edmonton, Alberta, Canada
🇨🇦Alberta Children's Hospital, Calgary, Alberta, Canada
Comparison of Metoclopramide and Ibuprofen for the Treatment of Acute Mountain Sickness
- Conditions
- Interventions
- First Posted Date
- 2012-01-31
- Last Posted Date
- 2020-09-02
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 300
- Registration Number
- NCT01522326
- Locations
- 🇳🇵
Manang Clinic of the Himalayan Rescue Association, Manang, District Of Manang, Nepal
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.