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AZD-5672

Generic Name
AZD-5672
Drug Type
Small Molecule
Chemical Formula
C32H38F2N2O5S2
CAS Number
780750-65-4
Unique Ingredient Identifier
61XQN688TW
Background

Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis.

A Study to Investigate the Potential for AZD5672 to Affect the Electrical Conduction Pathways in the Heart

Phase 1
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2009-04-24
Last Posted Date
2009-07-16
Lead Sponsor
AstraZeneca
Target Recruit Count
64
Registration Number
NCT00887770
Locations
🇬🇧

Research Site, London, United Kingdom

AZD5672 Bioavailability Study in Healthy Male and Female Subjects

Phase 1
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2009-03-30
Last Posted Date
2009-06-30
Lead Sponsor
AstraZeneca
Target Recruit Count
24
Registration Number
NCT00871767
Locations
🇬🇧

Research Site, Manchester, United Kingdom

AZD5672 Absolute Bioavailability Study

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2008-09-04
Last Posted Date
2010-12-02
Lead Sponsor
AstraZeneca
Target Recruit Count
26
Registration Number
NCT00746837
Locations
🇬🇧

Research Site, Harrow, London, United Kingdom

Drug Interaction Study - Effect of AZD5672 on the Pharmacokinetics of Digoxin

Phase 1
Completed
Conditions
Healthy Volunteers
Pharmacokinetics
Interventions
First Posted Date
2008-07-28
Last Posted Date
2010-12-02
Lead Sponsor
AstraZeneca
Target Recruit Count
24
Registration Number
NCT00723424
Locations
🇩🇪

Research Site, Berlin, Germany

Drug Interaction Study - Assess Pharmacokinetics of Both AZD5672 and Atorvastatin

Phase 1
Completed
Conditions
Healthy Volunteers
Pharmacokinetics
Interventions
First Posted Date
2008-07-28
Last Posted Date
2010-12-02
Lead Sponsor
AstraZeneca
Target Recruit Count
12
Registration Number
NCT00722956
Locations
🇬🇧

Research Site, London, United Kingdom

Safety Study of AZD5672 in Renally Impaired Subjects

Phase 1
Completed
Conditions
Renal Impairment
Interventions
First Posted Date
2008-07-15
Last Posted Date
2009-04-29
Lead Sponsor
AstraZeneca
Target Recruit Count
40
Registration Number
NCT00715702
Locations
🇩🇪

Research Site, München, Germany

A Proof of Concept and Dose Ranging Study in Patients With Rheumatoid Arthritis

Phase 2
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2008-07-11
Last Posted Date
2011-10-03
Lead Sponsor
AstraZeneca
Target Recruit Count
373
Registration Number
NCT00713544
Locations
🇺🇦

Research Site, Simferopol, Ukraine

Mass Balance and Metabolic Profiling of [14C]AZD5672 in Healthy Male Volunteers

Phase 1
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2008-07-08
Last Posted Date
2009-04-09
Lead Sponsor
AstraZeneca
Target Recruit Count
4
Registration Number
NCT00711074
Locations
🇬🇧

Research Site, Macclesfield, Cheshire, United Kingdom

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