Paroxetine
- Generic Name
- Paroxetine
- Brand Names
- Paxil, Pexeva
- Drug Type
- Small Molecule
- Chemical Formula
- C19H20FNO3
- CAS Number
- 61869-08-7
- Unique Ingredient Identifier
- 41VRH5220H
- Background
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. A unique feature of this...
- Indication
Paroxetine is indicated for the management of depression, obsessive-compulsive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, posttraumatic stress disorder. One form of paroxetine, commercially known as Brisdelle, is used to manage mild to moderate vasomotor symptoms of menopause. Off-label, paroxetine may be used for the tr...
- Associated Conditions
- Generalized Anxiety Disorder, Irritable Bowel Syndrome (IBS), Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premature Ejaculation, Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAD), Vasomotor Symptoms Associated With Menopause
- Associated Therapies
- -
PET (Positron Emission Tomography)/Public Speaking Study With A Combination Of 2 Medications In Social Anxiety Patients
- Conditions
- First Posted Date
- 2006-06-23
- Last Posted Date
- 2016-09-15
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 72
- Registration Number
- NCT00343707
- Locations
- 🇸🇪
GSK Investigational Site, Uppsala, Sweden
Naltrexone & SSRI in Alcoholics With Depression/PTSD
- Conditions
- Interventions
- First Posted Date
- 2006-06-20
- Last Posted Date
- 2016-02-05
- Lead Sponsor
- Yale University
- Target Recruit Count
- 88
- Registration Number
- NCT00338962
- Locations
- 🇺🇸
VA Connecticut Healthcare Systems, West Haven, Connecticut, United States
Study Evaluating the Effects of DVS SR and Paroxetine on the Pharmacokinetics of Desipramine in Healthy Subjects
- Conditions
- First Posted Date
- 2006-05-24
- Last Posted Date
- 2007-12-07
- Lead Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
- Target Recruit Count
- 20
- Registration Number
- NCT00329147
Efficacy and Safety Study of Seroquel SR in the Treatment of Generalized Anxiety Disorder
- Conditions
- First Posted Date
- 2006-05-08
- Last Posted Date
- 2008-12-22
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 800
- Registration Number
- NCT00322595
- Locations
- 🇸🇪
Research Site, Uppsala, Sweden
Neuropathic Pain Assessment Comparing Pregabalin and Paroxetine in Management of MS-induced Neuropathic Pain
- Conditions
- Interventions
- First Posted Date
- 2006-02-13
- Last Posted Date
- 2012-07-27
- Lead Sponsor
- University of Manitoba
- Target Recruit Count
- 75
- Registration Number
- NCT00291148
- Locations
- 🇨🇦
Multiple Sclerosis Clinic, Health Sciences Centre, Winnipeg, Manitoba, Canada
A Study Of A New Medicine (GW679769) For The Treatment Of Social Anxiety Disorder
- Conditions
- First Posted Date
- 2006-01-09
- Last Posted Date
- 2016-10-26
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 242
- Registration Number
- NCT00273039
- Locations
- 🇲🇽
GSK Investigational Site, Mexico, D.F., Mexico
Prazosin vs. Paroxetine in Combat Stress Symptoms in OIF/OEF Returnees
- Conditions
- Interventions
- First Posted Date
- 2005-12-05
- Last Posted Date
- 2009-12-03
- Lead Sponsor
- US Department of Veterans Affairs
- Target Recruit Count
- 210
- Registration Number
- NCT00261729
- Locations
- 🇺🇸
VA Puget Sound Health Care System, Seattle, Seattle, Washington, United States
Combination Of PAXIL Tablet And Benzodiazepines
- First Posted Date
- 2005-12-01
- Last Posted Date
- 2017-01-18
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 150
- Registration Number
- NCT00259883
- Locations
GSK Investigational Site
Paroxetine for Comorbid Social Anxiety Disorder and Alcoholism
- Conditions
- Interventions
- First Posted Date
- 2005-10-30
- Last Posted Date
- 2018-09-27
- Lead Sponsor
- Medical University of South Carolina
- Target Recruit Count
- 42
- Registration Number
- NCT00246441
- Locations
- 🇺🇸
Medical University of South Carolina, Institute of Psychiatry, Charleston, South Carolina, United States
Study of Paxil Use in Menopausal Women
- First Posted Date
- 2005-09-26
- Last Posted Date
- 2010-11-24
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 64
- Registration Number
- NCT00225914
- Locations
- 🇺🇸
MGH Center for Perinatal and Women's Mental Health, Boston, Massachusetts, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.