Bisoprolol

Generic Name
Bisoprolol
Brand Names
Ziac
Drug Type
Small Molecule
Chemical Formula
C18H31NO4
CAS Number
66722-44-9
Unique Ingredient Identifier
Y41JS2NL6U
Background

Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure. It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternati...

Indication

Bisoprolol is indicated for the treatment of mild to moderate hypertension. It may be used off-label to treat heart failure, atrial fibrillation, and angina pectoris.

Associated Conditions
Atrial Fibrillation, Cardiovascular Events, Chronic Stable Angina Pectoris, Heart Failure, Hypertension, Mild Hypertension, Premature Ventricular Contraction (PVC), Supraventricular Arrhythmias, Moderate Hypertension, Perioperative arrhythmia
Associated Therapies
-

Determination of Drug Levels for Pharmacotherapy of Heart Failure

First Posted Date
2023-09-13
Last Posted Date
2024-01-18
Lead Sponsor
University Hospital Ostrava
Target Recruit Count
100
Registration Number
NCT06035978
Locations
🇨🇿

University Hospital Ostrava, Ostrava, Czech Republic, Czechia

Once Versus Twice Bisoprolol Dosage Regimen in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft Surgery

First Posted Date
2023-02-15
Last Posted Date
2023-07-28
Lead Sponsor
Cairo University
Target Recruit Count
122
Registration Number
NCT05730413
Locations
🇪🇬

El-Demerdash Cardiac Academy Hospital, Cairo, Egypt

Treatment Effects of Bisoprolol and Verapamil in Symptomatic Patients With Non-obstructive Hypertrophic Cardiomyopathy

First Posted Date
2022-10-06
Last Posted Date
2024-06-14
Lead Sponsor
Morten Steen Kvistholm Jensen
Target Recruit Count
100
Registration Number
NCT05569382
Locations
🇩🇰

Department of Cardiology, Aarhus University Hospital, Aarhus N, Denmark

🇩🇰

Department of Cardiology, Odense University Hospital, Odense, Denmark

🇩🇰

Department of Cardiology, Zealand University Hospital, Roskilde, Denmark

and more 1 locations

Left Atrium Reservoir Function Modulation in Patients With Atrial Fibrillation: Digoxin Versus Beta Blocker

First Posted Date
2022-09-14
Last Posted Date
2022-09-16
Lead Sponsor
University of Monastir
Target Recruit Count
30
Registration Number
NCT05540600
Locations
🇹🇳

Fattouma Bourguiba University hospital, Monastir, Tunisia

Pharmacogenetic Study of Bisoprolol in Egyptian Patients With Acute Coronary Syndrome

Phase 2
Completed
Conditions
Interventions
First Posted Date
2022-09-10
Last Posted Date
2023-06-07
Lead Sponsor
Damanhour University
Target Recruit Count
127
Registration Number
NCT05536271
Locations
🇪🇬

Damanhour University, Damanhūr, Behira, Egypt

Randomized Trial to Examine a Differential Therapeutic Response in Symptomatic Patients With Non-obstructive Coronary Artery Disease

First Posted Date
2022-03-24
Last Posted Date
2022-03-24
Lead Sponsor
Charite University, Berlin, Germany
Target Recruit Count
132
Registration Number
NCT05294887
Locations
🇨🇭

Universitäres Herzzentrum Zürich, Universitätsspital Zürich, Zürich, Switzerland

🇩🇪

Kerckhoff-Klinik gGmbH, Bad Nauheim, Germany

🇩🇪

Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany

and more 12 locations

Bisoprolol Administration to Prevent Anthracycline-induced Cardiotoxicity

First Posted Date
2022-01-03
Last Posted Date
2022-01-03
Lead Sponsor
Shahid Beheshti University of Medical Sciences
Target Recruit Count
80
Registration Number
NCT05175066
Locations
🇮🇷

Rasool Akram hospital, Tehran, Iran, Islamic Republic of

Activation of Brown Adipose Tissue Metabolism Using Mirabegron

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2021-03-30
Last Posted Date
2024-12-09
Lead Sponsor
Université de Sherbrooke
Target Recruit Count
9
Registration Number
NCT04823442
Locations
🇨🇦

Centre de recherche du CHUS, Sherbrooke, Quebec, Canada

Comparative Study Between the Efficacy of Verapamil and Bisoprolol on Reduction of Bleeding During Endoscopic Sinus Surgery Under General Anaesthesia.

First Posted Date
2020-04-22
Last Posted Date
2021-12-03
Lead Sponsor
Assiut University
Target Recruit Count
135
Registration Number
NCT04356196
Locations
🇪🇬

Faculty of medicine Assiut university, Assiut, Egypt

Preventing Adverse Cardiac Events in COPD

First Posted Date
2019-04-17
Last Posted Date
2024-01-18
Lead Sponsor
The George Institute
Target Recruit Count
280
Registration Number
NCT03917914
Locations
🇦🇺

Westmead Hospital, Sydney, New South Wales, Australia

🇦🇺

Fiona Stanley Hospital, Murdoch, Western Australia, Australia

🇦🇺

Campbelltown Hospital, Campbelltown, New South Wales, Australia

and more 14 locations
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