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TAS-116

Generic Name
TAS-116
Drug Type
Small Molecule
Chemical Formula
C25H26N8O
CAS Number
1260533-36-5
Unique Ingredient Identifier
PLO044MUDZ
Background

TAS-116 is under investigation in clinical trial NCT02965885 (A Study of TAS-116 in Patients With Solid Tumors).

TAS-116 Plus Palbociclib in Breast and Rb-null Cancer

Phase 1
Recruiting
Conditions
Retinoblastoma Deficiency
Bladder Cancer
Treatment-Refractory Solid Tumors
SCLC
Advanced Breast Cancer
Soft Tissue Sarcoma
Endometrial Cancer
Interventions
First Posted Date
2022-12-19
Last Posted Date
2023-09-14
Lead Sponsor
Brown University
Target Recruit Count
27
Registration Number
NCT05655598
Locations
🇺🇸

Lifespan Cancer Institute, Providence, Rhode Island, United States

AB122 Platform Study

Phase 1
Recruiting
Conditions
Advanced or Metastatic Solid Tumor
Pancreatic Ductal Adenocarcinoma
Colorectal Cancer
Non-small Cell Lung Cancer
Gastric Cancer
Alveolar Soft Part Sarcoma
Esophageal Cancer
Head and Neck Cancer
Biliary Tract Cancer
Interventions
First Posted Date
2021-08-11
Last Posted Date
2024-02-16
Lead Sponsor
Taiho Pharmaceutical Co., Ltd.
Target Recruit Count
715
Registration Number
NCT04999761
Locations
🇯🇵

A site selected by Taiho Pharmaceutical Co., Ltd., Wakayama, Japan

A Study of TAS-116 in Patients With Solid Tumors

Phase 1
Completed
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2016-11-17
Last Posted Date
2024-06-27
Lead Sponsor
Taiho Oncology, Inc.
Target Recruit Count
31
Registration Number
NCT02965885
Locations
🇺🇸

University Hospitals Case Medical Center, Cleveland, Ohio, United States

🇮🇹

Regina Elena National Cancer Institute, Roma, Italy

🇬🇧

The Christie NHS Foundation Trust Institute of Cancer Sciences, University of Manchester, Manchester, United Kingdom

and more 9 locations
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