MedPath

Interferon Gamma

Generic Name
Interferon Gamma
Drug Type
Biotech
Unique Ingredient Identifier
P050J5FWC5
Background

Interferon gamma is a Type 1 inflammatory cytokine and the only type II interferon. It has antitumor properties, antiviral activities, and important immunoregulatory functions. The interferon is primarily produced by activated T lymphocytes and natural killer cells.

Associated Conditions
Serious infections

A Randomized Phase III Trial of Hyperthermic Isolated Limb Perfusion With Melphalan, Tumor Necrosis Factor, and Interferon-Gamma in Patients With Locally Advanced Extremity Melanoma

Phase 3
Completed
Conditions
Melanoma
First Posted Date
2002-12-10
Last Posted Date
2008-03-04
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
122
Registration Number
NCT00001296
Locations
🇺🇸

National Cancer Institute (NCI), Bethesda, Maryland, United States

A Phase IV Study of Recombinant Human Gamma Interferon in Patients With Chronic Granulomatous Diseases of Childhood

Phase 4
Completed
Conditions
Chronic Granulomatous Disease
First Posted Date
2002-12-10
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
100
Registration Number
NCT00001317
Locations
🇺🇸

National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland, United States

Treatment of Non-Tuberculous Mycobacterial Infections With Interferon Gamma

Phase 2
Completed
Conditions
Healthy
Mycobacterium Infections, Atypical
First Posted Date
2002-12-10
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
60
Registration Number
NCT00001318
Locations
🇺🇸

National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland, United States

A Randomized, Double-Blinded, Placebo-Controlled, Phase II Inhaled Interferon Gamma-1b and Antimycobacterials to Treat Pulmonary Mycobacterium Avium Complex Infections

Phase 2
Completed
Conditions
Mycobacterium Avium-Intracellulare Infection
First Posted Date
2001-07-25
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
20
Registration Number
NCT00021567
Locations
🇺🇸

National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland, United States

Interferon Gamma for Drug Resistant Tuberculosis

Phase 2
Completed
Conditions
Pneumonia
Pulmonary Tuberculosis
First Posted Date
1999-11-04
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
30
Registration Number
NCT00001407
Locations
🇺🇸

National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland, United States

Interferon Gamma to Treat Leukocyte Adhesion Deficiency Type I

Phase 2
Completed
Conditions
Leukocyte Adhesion Deficiency Syndrome
First Posted Date
1999-11-04
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
5
Registration Number
NCT00001905
Locations
🇺🇸

National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland, United States

Phase III Randomized Study of Interferon Gamma in Children With Severe, Congenital Osteopetrosis

Phase 3
Completed
Conditions
Osteopetrosis
First Posted Date
1999-10-19
Last Posted Date
2015-03-25
Lead Sponsor
FDA Office of Orphan Products Development
Target Recruit Count
30
Registration Number
NCT00004402
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