Pilocarpine
- Generic Name
- Pilocarpine
- Brand Names
- Betoptic Pilo, Isoptocarpine, Minims Pilocarpine Nitrate, Salagen, Vuity
- Drug Type
- Small Molecule
- Chemical Formula
- C11H16N2O2
- CAS Number
- 92-13-7
- Unique Ingredient Identifier
- 01MI4Q9DI3
- Background
Pilocarpine is a cholinergic muscarinic receptor agonist.
- Indication
Pilocarpine oral tablets are indicated for the treatment of dry mouth caused by Sjogren's Syndrome or radiotherapy for cancer of the head and neck.
...
- Associated Conditions
- Acute angle-closure glaucoma, Dry Mouth, Glaucoma, Closed-Angle, Increased Intra Ocular Pressure (IOP), Narrow-angle glaucoma, Ocular Hypertension, Open Angle Glaucoma (OAG), Presbyopia, Chronic open-angle glaucoma
- Associated Therapies
- -
Xerostomia in Patients With a Life-limiting Condition or Frailty
- First Posted Date
- 2022-08-18
- Last Posted Date
- 2022-08-18
- Lead Sponsor
- Maastricht University Medical Center
- Target Recruit Count
- 120
- Registration Number
- NCT05506137
A Study to Assess Safety and Efficacy in Participants Age 40 to 55 With Presbyopia (Old Eye) Who Receive AGN-190584 in Both Eyes Twice Daily
- First Posted Date
- 2021-07-30
- Last Posted Date
- 2023-03-21
- Lead Sponsor
- Allergan
- Target Recruit Count
- 230
- Registration Number
- NCT04983589
- Locations
- 🇺🇸
Martel Eye Medical Group /ID# 231332, Rancho Cordova, California, United States
🇺🇸North Valley Eye Medical Group, Inc. /ID# 231270, Mission Hills, California, United States
🇺🇸Global Research Management /ID# 231300, Glendale, California, United States
Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia
- Conditions
- Interventions
- First Posted Date
- 2020-12-19
- Last Posted Date
- 2023-09-07
- Lead Sponsor
- Ocuphire Pharma, Inc.
- Target Recruit Count
- 150
- Registration Number
- NCT04675151
- Locations
- 🇺🇸
Clinical Site 18, Saint Louis, Missouri, United States
🇺🇸Clinical Site 12, Laguna Hills, California, United States
🇺🇸Clinical Site 3, Pittsburg, Kansas, United States
Pilocarpine After Combined Cataract/Trabectome Surgery
- Conditions
- Interventions
- First Posted Date
- 2019-07-02
- Last Posted Date
- 2022-04-07
- Lead Sponsor
- Montefiore Medical Center
- Registration Number
- NCT04005079
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Pilocarpine Use After Kahook Goniotomy
- First Posted Date
- 2019-05-01
- Last Posted Date
- 2024-07-22
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 142
- Registration Number
- NCT03933631
- Locations
- 🇺🇸
Montefiore Wakefield Campus, Bronx, New York, United States
🇺🇸Montefiore Medical Center, Bronx, New York, United States
Measuring Sweat Glucose of Patients With Diabetes - The ENGAGE Study
- Conditions
- Interventions
- First Posted Date
- 2018-03-09
- Last Posted Date
- 2020-07-09
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 2
- Registration Number
- NCT03460964
- Locations
- 🇺🇸
UCSD Altman Clinical and Translational Research Institute, San Diego, California, United States
🇺🇸UCSD, San Diego, California, United States
Effect of Pilocarpine in Patients With Xerostomia
- First Posted Date
- 2016-12-05
- Last Posted Date
- 2016-12-05
- Lead Sponsor
- University of Sao Paulo
- Target Recruit Count
- 80
- Registration Number
- NCT02982577
- Locations
- 🇧🇷
University of São Paulo, Ribeirao Preto, São Paulo, Brazil
Investigating the Stability, Variability and Mechanism of Incorporation of Lipid Mediators Into Eccrine Sweat
- Conditions
- Interventions
- First Posted Date
- 2016-10-18
- Last Posted Date
- 2018-06-01
- Lead Sponsor
- USDA, Western Human Nutrition Research Center
- Target Recruit Count
- 14
- Registration Number
- NCT02935894
- Locations
- 🇺🇸
Western Human Nutrition Research Center, Davis, California, United States
Anterior Segment Imaging With Ultrahigh-resolution OCT in Patients With Glaucoma and PEX - a Pilot Study
- First Posted Date
- 2016-08-12
- Last Posted Date
- 2022-04-07
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 90
- Registration Number
- NCT02865473
- Locations
- 🇦🇹
Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
The Diurnal and Nocturnal Effect of Pilocarpine on Intraocular Pressure and Ocular Perfusion Pressure
- Conditions
- Interventions
- First Posted Date
- 2016-04-28
- Last Posted Date
- 2019-11-07
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 27
- Registration Number
- NCT02754570
- Locations
- 🇺🇸
University of Colorado Denver Eye Hospital, Denver, Colorado, United States
Drug Development Updates
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