Thiopental

Generic Name
Thiopental
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C11H18N2O2S
CAS Number
76-75-5
Unique Ingredient Identifier
JI8Z5M7NA3
Background

A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not produce any excitation but has poor an...

Indication

For use as the sole anesthetic agent for brief (15 minute) procedures, for induction of anesthesia prior to administration of other anesthetic agents, to supplement regional anesthesia, to provide hypnosis during balanced anesthesia with other agents for analgesia or muscle relaxation, for the control of convulsive states during or following inhalation anest...

Associated Conditions
Seizures
Associated Therapies
-
Clinical Trials
Related News

The Effects of Propofol and Thiopental on Nitric Oxide Production and Release in Erythrocytes

Not Applicable
Completed
Conditions
Effect of Drug
Interventions
Drug: Thiopental
Drug: Propofol
First Posted Date
2024-07-03
Last Posted Date
2024-08-01
Lead Sponsor
Melike Cengiz
Target Recruit Count
12
Registration Number
NCT06485388
Locations
🇹🇷

Akdeniz University School of Medicine, Department of Anesthesiology and Intensive Care, Turkey, Antalya, Turkey

Ketamine Versus Low Dose Thiopental for Induction of Anesthesia in Septic Shock

Phase 3
Completed
Conditions
Septic Shock
Interventions
Drug: Ketamine
Drug: Thiopental
First Posted Date
2017-04-07
Last Posted Date
2018-07-10
Lead Sponsor
Cairo University
Target Recruit Count
26
Registration Number
NCT03104140
Locations
🇪🇬

Cairo University, Cairo, Egypt

The Effects of Remifentanil and Remifentanil-Alfentanil Administration in Children

First Posted Date
2015-07-01
Last Posted Date
2015-07-07
Lead Sponsor
Hallym University Medical Center
Target Recruit Count
102
Registration Number
NCT02486926

Comparative Effect of Theipoental and Propofol in IVF Outcome

Phase 4
Completed
Conditions
Subfertility
Interventions
Drug: Thiopental
Drug: Propofol
First Posted Date
2015-03-04
Last Posted Date
2015-03-04
Lead Sponsor
Aristotle University Of Thessaloniki
Target Recruit Count
180
Registration Number
NCT02377778
Locations
🇬🇷

Unit for Human Reproduction, 1st Dept of OB/Gyn, Medical School, Aristotle UNiversity of Thessaloniki, Thessaloniki, Greece

The Cortisol Levels During Cardiac Surgery. The Comparison Between Etomidate and Thiopentone

First Posted Date
2011-12-20
Last Posted Date
2014-05-23
Lead Sponsor
Mahidol University
Target Recruit Count
92
Registration Number
NCT01495949
Locations
🇹🇭

Siriraj Hospital Mahidol University, Bangkok, Thailand

Onset Time of Thiopental Versus Propofol in the Elderly

Phase 4
Completed
Conditions
Induction of Anaesthesia
Age
Interventions
Drug: Thiopental
Drug: Propofol
First Posted Date
2009-08-25
Last Posted Date
2010-03-09
Lead Sponsor
Rigshospitalet, Denmark
Target Recruit Count
78
Registration Number
NCT00965107
Locations
🇩🇰

Department of Anesthesia, Center of Head and Orthopedics, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark

🇩🇰

Department of Anesthesia, Juliane Marie Center, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark

Comparison of Effectiveness of Pentobarbital and Thiopental in Patients With Refractory Intracranial Hypertension

Phase 3
Terminated
Conditions
Traumatic Brain Injury
Interventions
Drug: Pentobarbital
Drug: thiopental
First Posted Date
2008-02-25
Last Posted Date
2008-02-25
Lead Sponsor
Hospital Universitari Son Dureta
Target Recruit Count
44
Registration Number
NCT00622570
Locations
🇪🇸

Son Dureta Hospital, Palma, Balearic Island, Spain

GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence

Not Applicable
Completed
Conditions
Alcoholism
Interventions
Drug: Placebo
Drug: Thiopental
First Posted Date
2008-02-11
Last Posted Date
2017-03-17
Lead Sponsor
Yale University
Target Recruit Count
73
Registration Number
NCT00611767
Locations
🇺🇸

VA Connecticut Healthcare System, West Haven, Connecticut, United States

Neuroimaging the Effects of Intravenous Anesthetic on Amygdala Dependent Memory Processes

Phase 4
Terminated
Conditions
Healthy
Interventions
Drug: Placebo
Drug: Propofol
Drug: Thiopental
First Posted Date
2007-07-20
Last Posted Date
2021-07-15
Lead Sponsor
Weill Medical College of Cornell University
Target Recruit Count
60
Registration Number
NCT00504894
Locations
🇺🇸

Weill Cornell Medical College, New York, New York, United States

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