Dopamine

Background: One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.

Indication: For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure

Associated Conditions: Arrhythmia, Circulatory collapse and shock, Hypotension caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction, Urine flow decreased caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction, Decreased cardiac output caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction

Renal Optimization Strategies Evaluation in Acute Heart Failure and Reliable Evaluation of Dyspnea in the Heart Failure Network (ROSE) Study

Phase 2

Completed

Locations: 🇺🇸
University of Utah Health Sciences Center, Murry, Utah, United States
🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
🇺🇸
University of Vermont- Fletcher Allen Health Care, Burlington, Vermont, United States

Phase 1

Completed

Conditions: Infant, Premature
Blood Pressure
Infant, Newborn
Infant, Low Birth Weight
Infant, Small for Gestational Age
Hypotension

Interventions: Drug: Infusion Placebo
Drug: Dopamine
Drug: Syringe Placebo
Drug: Hydrocortisone

Locations: 🇺🇸
Yale University, New Haven, Connecticut, United States
🇺🇸
Wayne State University, Detroit, Michigan, United States
🇺🇸
RTI International, Durham, North Carolina, United States