Moxonidine

Generic Name
Moxonidine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C9H12ClN5O
CAS Number
75438-57-2
Unique Ingredient Identifier
CC6X0L40GW
Background

Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown to prese...

Indication

For the treatment of mild to moderate essential or primary hypertension . Effective as most first-line antihypertensives when used as monotherapy .

Associated Conditions
Hypertension
Associated Therapies
-

Sympathetic Mechanisms in Obesity-Crossover Design

First Posted Date
2022-04-06
Last Posted Date
2024-02-20
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
12
Registration Number
NCT05312892
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Moxonidine Effects on Neuropeptide Y

Phase 4
Completed
Conditions
Interventions
First Posted Date
2021-12-07
Last Posted Date
2021-12-07
Lead Sponsor
Aristotle University Of Thessaloniki
Target Recruit Count
90
Registration Number
NCT05147753

Autonomic Determinants of POTS - Pilot1

Early Phase 1
Active, not recruiting
Conditions
Interventions
First Posted Date
2019-08-08
Last Posted Date
2024-11-12
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
48
Registration Number
NCT04050410
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Comparative Effects of Moxonidine on Bone Metabolism, Vascular and Cellular Aging in Hypertensive Postmenopausal Women

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2015-02-04
Last Posted Date
2021-09-01
Lead Sponsor
National Research Center for Preventive Medicine
Target Recruit Count
114
Registration Number
NCT02355821
Locations
🇷🇺

National Research Center for Preventive Medicine, Moscow, Russian Federation

Moxonidine for Prevention of Post-ablation AFib Recurrences

Phase 4
Completed
Conditions
Interventions
First Posted Date
2013-02-15
Last Posted Date
2014-05-06
Lead Sponsor
Spyridon Deftereos
Target Recruit Count
150
Registration Number
NCT01791699
Locations
🇬🇷

Red Cross Hospital, Athens, Greece

🇬🇷

Evangelismos General Hospital, Athens, Greece

🇬🇷

Athens General Hospital "G. Gennimatas", Athens, Greece

Alleviating the Metabolic Side Effects of Antipsychotic Medications

Phase 4
Withdrawn
Conditions
Interventions
First Posted Date
2012-03-30
Last Posted Date
2019-04-24
Lead Sponsor
Baker Heart and Diabetes Institute
Registration Number
NCT01567124
Locations
🇦🇺

Ballarat Health Service Psychiatric Services, Ballarat, Victoria, Australia

🇦🇺

Alfred and Baker Medical Unit - Alfred Hospital, Melbourne, Victoria, Australia

🇦🇺

Baker IDI Heart & Diabetes Institute, Melbourne, Victoria, Australia

and more 1 locations

Polycystic Ovary Syndrome - Improving Outcomes

Phase 4
Completed
Conditions
Interventions
First Posted Date
2012-01-05
Last Posted Date
2018-11-02
Lead Sponsor
Baker Heart and Diabetes Institute
Target Recruit Count
42
Registration Number
NCT01504321
Locations
🇦🇺

Heart Centre, Alfred Hospital, Prahran, Victoria, Australia

The Effect of Moxonidine on Blood Pressure and Regression of Early Target Organ Damage in Young Subjects With Abdominal Obesity and Hypertension

First Posted Date
2011-05-26
Last Posted Date
2012-02-03
Lead Sponsor
Baker Heart and Diabetes Institute
Target Recruit Count
100
Registration Number
NCT01360710
Locations
🇦🇺

BakerIDI Heart and Diabetes Institute, Prahran, Victoria, Australia

Treatment of Adiposity Related hypErTension (TARGET)

First Posted Date
2010-06-07
Last Posted Date
2012-02-24
Lead Sponsor
UMC Utrecht
Target Recruit Count
32
Registration Number
NCT01138423
Locations
🇳🇱

UMC Utrecht, Utrecht, Netherlands

Sympathetic Nervous System Inhibition for the Treatment of Diabetic Kidney Disease

Phase 4
Completed
Conditions
Interventions
First Posted Date
2010-03-29
Last Posted Date
2023-09-14
Lead Sponsor
Baker Heart and Diabetes Institute
Target Recruit Count
48
Registration Number
NCT01094769
Locations
🇦🇺

Alfred & Baker Medical Unit, Melbourne, Victoria, Australia

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