MedPath

N-(Phosphonoacetyl)-L-Ornithine

Generic Name
N-(Phosphonoacetyl)-L-Ornithine
Drug Type
Small Molecule
Chemical Formula
C7H15N2O6P
CAS Number
63446-55-9
Clinical Trials
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The Effectiveness of L-ornithine-L-aspartate (LOLA) on Plasma Ammonia in Cirrhotic Patients After TIPS

Phase 2
Completed
Conditions
Decompensated Cirrhosis
Portal Hypertension
Bleeding Varices
Refractory Ascites
Interventions
First Posted Date
2011-09-27
Last Posted Date
2012-12-19
Lead Sponsor
Air Force Military Medical University, China
Target Recruit Count
40
Registration Number
NCT01440829
Locations
🇨🇳

Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi, China

Efficacy of L-Ornithine L-Aspartate in Acute Hepatic Encephalopathy.

Phase 4
Completed
Conditions
Hepatic Encephalopathy
Interventions
First Posted Date
2010-01-01
Last Posted Date
2021-05-10
Lead Sponsor
Centro Regional para el Estudio de las Enfermedades Digestivas
Target Recruit Count
30
Registration Number
NCT01041755
Locations
🇲🇽

Hospital Universitario "José Eleuterio González", Monterrey, Nuevo León, Mexico

Therapeutic Efficacy of Oral L-Ornithine-L-Aspartate on Minimal Encephalopathy

Phase 4
Conditions
Hepatic Encephalopathy
Interventions
Drug: placebo
First Posted Date
2009-05-12
Last Posted Date
2009-06-10
Lead Sponsor
Hospital de Clinicas de Porto Alegre
Target Recruit Count
96
Registration Number
NCT00896831
Locations
🇧🇷

Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil

Efficacy of Combined Oral L-ornithine-L-aspartate and Lactulose in Patients With Hepatic Encephalopathy

Phase 4
Completed
Conditions
Hepatic Encephalopathy
Interventions
First Posted Date
2008-08-22
Last Posted Date
2020-09-04
Lead Sponsor
Mahidol University
Target Recruit Count
35
Registration Number
NCT00740142
Locations
🇹🇭

Siriraj Hospital, Mahidol University, Bangkok, Thailand

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