Candesartan

Generic Name
Candesartan
Brand Names
Atacand, Atacand Hct
Drug Type
Small Molecule
Chemical Formula
C24H20N6O3
CAS Number
139481-59-7
Unique Ingredient Identifier
S8Q36MD2XX
Background

Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of candesartan cilexetil.

Indication

May be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Candesartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction an...

Associated Conditions
Hypertension, NYHA Functional Class II-IV Heart Failure
Associated Therapies
-

An ACE Inhibitor (Perindopril) or an Angiotensin Receptor Blocker (Candesartan) as a Treatment for Methamphetamine Dependence

First Posted Date
2010-02-04
Last Posted Date
2022-04-26
Lead Sponsor
Baylor College of Medicine
Target Recruit Count
80
Registration Number
NCT01062451
Locations
🇺🇸

Michael E. DeBakey VA Medical Center, Houston, Texas, United States

Impact of Diabetes on Left Ventricular Remodeling

First Posted Date
2010-01-20
Last Posted Date
2012-12-17
Lead Sponsor
University of Alabama at Birmingham
Target Recruit Count
72
Registration Number
NCT01052272
Locations
🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

Angiotensin Receptor Blockade as an Anti-Fibrotic Intervention in Patients With Chronic Hepatitis C

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2009-07-02
Last Posted Date
2012-04-25
Lead Sponsor
Kaiser Permanente
Registration Number
NCT00930995
Locations
🇺🇸

Kaiser Permanente, Sacramento, California, United States

Evaluation of the Pharmacokinetic Interaction Between Candesartan and Felodipine After Ingestion of a Specific Meal

First Posted Date
2009-05-20
Last Posted Date
2010-12-07
Lead Sponsor
AstraZeneca
Target Recruit Count
36
Registration Number
NCT00905333
Locations
🇧🇷

Research Site, Americana, Brazil

Candesartan Versus Propranolol for Migraine Prevention

First Posted Date
2009-04-21
Last Posted Date
2013-12-24
Lead Sponsor
Norwegian University of Science and Technology
Target Recruit Count
72
Registration Number
NCT00884663
Locations
🇳🇴

Norwegian National Headache Centre, St. Olavs University Hospital, Trondheim, Norway

Bioequivalence Study in Healthy Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2009-02-16
Last Posted Date
2010-12-07
Lead Sponsor
AstraZeneca
Target Recruit Count
36
Registration Number
NCT00844324
Locations
🇬🇧

Research Site, Harrow, United Kingdom

Efficacy of Candesartan on Symptomatic Heart Failure in Treating Diabetic and Hypertensive Patients.

Phase 3
Completed
Conditions
Interventions
First Posted Date
2008-10-20
Last Posted Date
2010-06-22
Lead Sponsor
Takeda
Target Recruit Count
22
Registration Number
NCT00775840

The Potential of Candesartan to Retard the Progression of Aortic Stenosis

First Posted Date
2008-06-18
Last Posted Date
2009-05-19
Lead Sponsor
University of Helsinki
Target Recruit Count
120
Registration Number
NCT00699452
Locations
🇫🇮

Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland

Study to Characterize the Long-term Clinical Experience of Atacand in Hypertensive Children Ages 1 to<11 Years (Hypertension in Pediatrics)

Phase 3
Completed
Conditions
Interventions
First Posted Date
2008-06-04
Last Posted Date
2011-07-12
Lead Sponsor
AstraZeneca
Target Recruit Count
35
Registration Number
NCT00690612
Locations
🇺🇦

Research Site, Kyiv, Ukraine

Observational Usage and Efficacy Study of Candesartan in Heart Failure Treatment in France

Completed
Conditions
Interventions
First Posted Date
2008-05-19
Last Posted Date
2010-12-02
Lead Sponsor
AstraZeneca
Target Recruit Count
450
Registration Number
NCT00679640
Locations
🇫🇷

Research Site, Maisons Laffitte, Yvelines, France

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