Etoricoxib
- Generic Name
- Etoricoxib
- Drug Type
- Small Molecule
- Chemical Formula
- C18H15ClN2O2S
- CAS Number
- 202409-33-4
- Unique Ingredient Identifier
- WRX4NFY03R
- Background
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid. It is approved in more than 60 countries worldwide but not in the US.
- Indication
For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
- Associated Conditions
- Ankylosing Spondylitis (AS), Gout, Osteoarthritis (OA), Rheumatoid Arthritis, Moderate Pain
"NSAIDs in Acute Achilles Tendinopathy: Effect on Pain Control, Leg Stiffness and Functional Recovery in Athletes"
- First Posted Date
- 2008-11-17
- Last Posted Date
- 2013-08-06
- Lead Sponsor
- Argentine Tennis Association
- Target Recruit Count
- 56
- Registration Number
- NCT00792376
- Locations
- 🇦🇷
Argentine Tennis Association, Buenos Aires, Argentina
A Study of MK0663/Etoricoxib for Post-Abdominal Hysterectomy Surgery Pain (0663-097)(COMPLETED)
- Conditions
- Acute Pain Following a Total Abdominal Hysterectomy
- Interventions
- First Posted Date
- 2008-11-11
- Last Posted Date
- 2022-02-09
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 430
- Registration Number
- NCT00788710
Study to Evaluate the Efficacy of Pre-operative Administration of Etoricoxib 120 mg, Etoricoxib 120 mg and Paracetamol 1 g Combination or Placebo in the Treatment of Postoperative Pain in Patients Undergoing Gynaecologic Laparoscopic Surgery
- First Posted Date
- 2008-10-01
- Last Posted Date
- 2012-01-31
- Lead Sponsor
- East Tallinn Central Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT00763685
- Locations
- 🇪🇪
East Tallinn Central Hospital, Tallinn, Estonia
Patient-Reported Effectiveness and Safety of Etoricoxib in Osteoarthritis (OA)(0663-113)
- First Posted Date
- 2008-09-23
- Last Posted Date
- 2022-02-09
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 500
- Registration Number
- NCT00757627
Etoricoxib in Ear Nose Throat Surgery
- Conditions
- Tonsillectomy
- Interventions
- Drug: Administration of placebo
- First Posted Date
- 2008-09-22
- Last Posted Date
- 2008-09-22
- Lead Sponsor
- University of Regensburg
- Target Recruit Count
- 90
- Registration Number
- NCT00756873
- Locations
- 🇩🇪
Weiden Clinic, Weiden i.d. OPf., Germany
🇩🇪Universtiy Hospital Regensburg, Regensburg, Germany
Study Assessing the Efficacy of Etoricoxib in Female Patients With Fibromyalgia
- First Posted Date
- 2008-09-19
- Last Posted Date
- 2012-08-10
- Lead Sponsor
- Meir Medical Center
- Target Recruit Count
- 80
- Registration Number
- NCT00755521
- Locations
- 🇮🇱
Department of Medicine 'D', Meir Medical Center, Kfar-Saba, Israel
Randomized Placebo Controlled Trial With Etoricoxib That is Taken to Prevent the Yom Kippur Headache
- First Posted Date
- 2008-09-16
- Last Posted Date
- 2008-09-16
- Lead Sponsor
- Shaare Zedek Medical Center
- Target Recruit Count
- 200
- Registration Number
- NCT00752921
- Locations
- 🇮🇱
Shaare Zedek Medical Center, Jerusalem, Israel
Modulation of the Surgical Inflammatory Response by Etoricoxib
- Conditions
- PainPostoperative PainOsteoarthritis, Hip
- Interventions
- Drug: Placebo for Etoricoxib 60 mg
- First Posted Date
- 2008-09-04
- Last Posted Date
- 2020-12-14
- Lead Sponsor
- University of Erlangen-Nürnberg Medical School
- Target Recruit Count
- 23
- Registration Number
- NCT00746720
- Locations
- 🇩🇪
HELIOS Klinikum Berlin, Berlin, Germany
The Effect of Anti-inflammatory Analgesics on Pain Following Hallux Valgus Surgery
- First Posted Date
- 2008-08-13
- Last Posted Date
- 2010-01-20
- Lead Sponsor
- Karolinska Institutet
- Target Recruit Count
- 100
- Registration Number
- NCT00733421
- Locations
- 🇸🇪
Foot & Ancle Surgical Center, Stockholm, Sweden
A Study to Asses the Effect of MK0663 in the Treatment of Patients With Postoperative Dental Pain (0663-092)
- Conditions
- Postoperative Dental Pain
- First Posted Date
- 2008-06-10
- Last Posted Date
- 2022-02-09
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 588
- Registration Number
- NCT00694369
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.