MedPath

Avagacestat

Generic Name
Avagacestat
Drug Type
Small Molecule
Chemical Formula
C20H17ClF4N4O4S
CAS Number
1146699-66-2
Unique Ingredient Identifier
TQ44WWY45Q
Background

Avagacestat has been investigated for the basic science and treatment of Alzheimer Disease.

A Phase II, Multicenter, Double Blind, Placebo-Controlled Safety, Tolerability Study of BMS-708163 in Patients With Mild to Moderate Alzheimer's Disease

Phase 2
Completed
Conditions
Alzheimer's Disease
Interventions
Drug: Placebo
First Posted Date
2008-12-17
Last Posted Date
2015-10-12
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
209
Registration Number
NCT00810147
Locations
🇺🇸

Yale University School Of Medicine, New Haven, Connecticut, United States

🇺🇸

Global Medical Institutes, Llc, Princeton, New Jersey, United States

🇺🇸

University Of Rochester, Rochester, New York, United States

and more 33 locations

Drug Interaction Study With a Potential Alzheimer's Disease Compound

Phase 1
Completed
Conditions
Alzheimer Disease
Interventions
Drug: Interacting drugs - Cooperstown Cocktail (midazolam, warfarin, (+ vitamin K), caffeine, omeprazole and dextromethorphan)
Drug: BMS-708163 + Cooperstown Cocktail
First Posted Date
2008-08-01
Last Posted Date
2008-11-05
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
22
Registration Number
NCT00726726
Locations
🇺🇸

Bristol-Myers Squibb Clinical Pharmacology Unit, Hamilton, New Jersey, United States

© Copyright 2025. All Rights Reserved by MedPath