Botulinum toxin type A

Generic Name: Botulinum toxin type A

Brand Names: Botox, Botox Cosmetic, Dysport, Jeuveau, Xeomin, Nuceiva

Drug Type: Biotech

Chemical Formula: -

CAS Number: 93384-43-1

Unique Ingredient Identifier: 0A6JH35GMQ

Background: In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use. With a wide variety of applications and favourable safety profile, Botulinum toxin A injection is a minimally invasive and promising treatment for cosmetic imperfections, muscle spasms, and other condit...

Indication: Botulinum toxin A is indicated for a variety of conditions, depending on the preparations. Cosmetically, it is used for the treatment of facial fine lines and wrinkles, specifically for upper facial rhytides, including forehead, lateral canthus, and glabellar lines.
...

Associated Conditions: Bladder pain, Blepharospasm, Cervical Dystonia, Chronic Migraine, Diabetic Neuropathies, Epicondylitis, Equinus deformity of foot, acquired, Facial Skin Wrinkles, Glabellar Frown Lines (GL), Lower Limb Spasticity, Myofascial Pain Syndrome, Neurogenic Detrusor Overactivity, Neurogenic Thoracic Outlet Syndrome, Overactive Bladder Syndrome (OABS), Post Stroke Pain, Postherpetic Neuralgia, Sialorrhea, Spasticity, Spinal Cord Injuries, Strabismus, TMJ Disorders, Trigeminal Neuralgia (TN), Upper Limb Spasticity, Urinary Incontinence (UI), Hypertonicity disorders of the 7th nerve, Moderate Glabellar Frown Lines (GL), Severe Glabellar Frown Lines (GL), Severe axillary hyperhidrosis

Associated Therapies: -

Clinical Trials

SURGERY VS BOTULINUM TOXIN ON QUALITY OF LIFE IN STROKE PATIENTS: RANDOMIZED TRIAL

Not Applicable

Recruiting

Conditions: Stroke

Interventions: Drug: Botulinum Toxin A
Procedure: spastic hand sugery

First Posted Date: 2024-04-30

Last Posted Date: 2024-04-30

Lead Sponsor: Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental

Target Recruit Count: 44

Registration Number: NCT06392633

Locations: 🇪🇸
University of Granada, Granada, Spain

Assessing the Impact of Botulinum Toxin Type A on Facial Wrinkles: A Comprehensive Clinical Investigation

Recruiting

Conditions: Wrinkle

Interventions: Drug: Botulinum toxin type A

First Posted Date: 2024-04-25

Last Posted Date: 2024-05-24

Lead Sponsor: Global Aesthetics LLC

Target Recruit Count: 500

Registration Number: NCT06385171

Locations: 🇺🇸
Global Aesthetics LLC, Lubbock, Texas, United States

Botulinum Toxin Injection in the UES for R-CPD

Phase 4

Not yet recruiting

Conditions: Retrograde Cricopharyngeus Dysfunction

Interventions: Drug: Sodium Chloride 0.9% Inj
Drug: botulinum toxin type A

First Posted Date: 2024-04-10

Last Posted Date: 2024-04-10

Lead Sponsor: AZ Delta

Target Recruit Count: 30

Registration Number: NCT06356025

Effectiveness of Botulinum Toxin A in Preventing Scar Formation and Initial Exploration of "Optimal Concentration"

Early Phase 1

Active, not recruiting

Conditions: Scar

Interventions: Drug: Botulinum toxin type A

First Posted Date: 2024-04-05

Last Posted Date: 2024-04-05

Lead Sponsor: Qilu Hospital of Shandong University

Target Recruit Count: 50

Registration Number: NCT06349733

Locations: 🇨🇳
Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, China

Intradermal BoNT-A Treatment in Erythematotelangiectatic Rosacea

Phase 4

Completed

Conditions: Erythematotelangiectatic Rosacea

Interventions: Drug: Placebo
Drug: Botulinum toxin A

First Posted Date: 2024-03-26

Last Posted Date: 2024-03-29

Lead Sponsor: Istanbul Training and Research Hospital

Target Recruit Count: 30

Registration Number: NCT06331533

Locations: 🇹🇷
Istanbul Training and Research Hospital, Istanbul, Turkey

Ultrasound-guided Botulinum Toxin Injection on Cricopharyngeal Muscle Dysfunction

Not Applicable

Not yet recruiting

Conditions: Cricopharyngeal Achalasia

Interventions: Drug: botulinum toxin type A
Procedure: Injection

First Posted Date: 2024-03-25

Last Posted Date: 2024-03-25

Lead Sponsor: Copka Sonpashan

Target Recruit Count: 30

Registration Number: NCT06328556

Safety and Efficacy of Botulinum Toxin A in Patients With Trigeminal Neuralgia

Phase 3

Recruiting

Conditions: Trigeminal Neuralgia

Interventions: Other: Isotonic saline
Drug: Botulinum toxin A

First Posted Date: 2024-03-18

Last Posted Date: 2024-03-18

Lead Sponsor: Henrik Schytz

Target Recruit Count: 80

Registration Number: NCT06315790

Locations: 🇩🇰
Danish Headache Center, Glostrup, Denmark

Comparative Study of the Effects of Dry Needling and Botulinum Toxin Type A as a Treatment for Lower Limb Post-stroke Spasticity

Phase 2

Not yet recruiting

Conditions: Stroke

Interventions: Other: Dry Needling
Drug: Botulinum toxin type A

First Posted Date: 2024-03-06

Last Posted Date: 2024-06-24

Lead Sponsor: Universiteit Antwerpen

Target Recruit Count: 90

Registration Number: NCT06296082

Locations: 🇪🇸
Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain
🇨🇦
Jewish Rehabilitation Hospital, Montréal, Quebec, Canada
🇧🇪
Universiteit Antwerpen, Antwerpen, Flandes, Belgium