Curcumin

Generic Name
Curcumin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C21H20O6
CAS Number
458-37-7
Unique Ingredient Identifier
IT942ZTH98
Background

Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in Curcuma xanthorrhiza oil. It is a highly pleiotropic molecule that exhibits antibacterial, anti-inflammatory, hypoglycemic, antioxidant, wound-healing, and antimicrobial activities . Due to these properties, curcumin has been investigated for...

Indication

No approved therapeutic indications.

Associated Conditions
-
Associated Therapies
-
Clinical Trials
Related News

Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy

Phase 3
Recruiting
Conditions
Prostate Cancer
Interventions
Drug: Curcumin
Drug: placebo
First Posted Date
2014-02-17
Last Posted Date
2023-09-18
Lead Sponsor
yair lotan
Target Recruit Count
608
Registration Number
NCT02064673
Locations
🇺🇸

UT Southwestern Medical Center, Dallas, Texas, United States

Adjunctive Curcumin for Symptomatic Adolescents With Bipolar Disorder: Brain and Body Considerations

Phase 2
Terminated
Conditions
Bipolar Disorder
Interventions
Drug: Curcumin
First Posted Date
2013-08-23
Last Posted Date
2018-07-24
Lead Sponsor
Sunnybrook Health Sciences Centre
Target Recruit Count
7
Registration Number
NCT01928043
Locations
🇨🇦

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

Effect of Oral Supplementation With Curcumin (Turmeric) in Patients With Proteinuric Chronic Kidney Disease

Phase 3
Completed
Conditions
Proteinuria
Interventions
Drug: Curcumin
First Posted Date
2013-04-15
Last Posted Date
2014-07-24
Lead Sponsor
Instituto Nacional de Cardiologia Ignacio Chavez
Target Recruit Count
120
Registration Number
NCT01831193
Locations
🇲🇽

Instituto Nacional de Cardiologia Ignacio Chavez, Mexico city, DF, Mexico

Curcumin and Yoga Therapy for Those at Risk for Alzheimer's Disease

First Posted Date
2013-03-14
Last Posted Date
2020-09-17
Lead Sponsor
VA Office of Research and Development
Target Recruit Count
80
Registration Number
NCT01811381
Locations
🇺🇸

VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles, California, United States

Efficacy and Safety Curcumin in Depression

Phase 4
Completed
Conditions
Major Depression
Interventions
Drug: curcumin
First Posted Date
2012-12-17
Last Posted Date
2013-02-07
Lead Sponsor
Vladimir Lerner
Target Recruit Count
40
Registration Number
NCT01750359
Locations
🇮🇱

Tirat Carmel Mental Health Center, Tirat Carmel, Israel

Phase II Study of Curcumin vs Placebo for Chemotherapy-Treated Breast Cancer Patients Undergoing Radiotherapy

Phase 2
Completed
Conditions
Breast Cancer
Interventions
Drug: Placebo
Drug: Curcumin
First Posted Date
2012-12-04
Last Posted Date
2019-09-18
Lead Sponsor
Andrew H Miller
Target Recruit Count
30
Registration Number
NCT01740323
Locations
🇺🇸

Emory University, Atlanta, Georgia, United States

Study of Curcumin, Vorinostat, and Sorafenib

First Posted Date
2012-05-30
Last Posted Date
2012-10-19
Lead Sponsor
M.D. Anderson Cancer Center
Registration Number
NCT01608139

Effects of Curcumin on Vascular Reactivity

Phase 1
Completed
Conditions
Healthy Volunteers (Middle-aged Smokers)
Interventions
Drug: Curcumin
First Posted Date
2012-03-05
Last Posted Date
2014-07-08
Lead Sponsor
University Hospital, Clermont-Ferrand
Target Recruit Count
21
Registration Number
NCT01543386
Locations
🇫🇷

CHU Clermont-Ferrand, Clermont-Ferrand, France

Dietary Supplement of Curcumin in Subjects With Active Relapsing Multiple Sclerosis Treated With Subcutaneous Interferon Beta 1a

First Posted Date
2012-01-23
Last Posted Date
2019-01-22
Lead Sponsor
Merck KGaA, Darmstadt, Germany
Target Recruit Count
80
Registration Number
NCT01514370
Locations
🇮🇹

Investigational Site, Naples, Italy

18-Month Study of Memory Effects of Curcumin

First Posted Date
2011-06-28
Last Posted Date
2020-03-03
Lead Sponsor
University of California, Los Angeles
Target Recruit Count
46
Registration Number
NCT01383161
Locations
🇺🇸

UCLA Longevity Center, Los Angeles, California, United States

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